Dillon, Joseph S Kulke, Matthew H Hörsch, Dieter Anthony, Lowell B Warner, Richard R P Bergsland, Emily Welin, Staffan O'Dorisio, Thomas M Kunz, Pamela L McKee, Chad
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Published in
Journal of gastrointestinal cancer
Telotristat ethyl is approved to treat carcinoid syndrome diarrhea in combination with somatostatin analogs. In TELESTAR and TELECAST phase III studies, patients with carcinoid syndrome received telotristat ethyl 250 or 500 mg 3 times per day (tid) or placebo tid in addition to somatostatin analogs. The aim of this prespecified analysis was to exam...
Avoka, James Atampiiga Dun-Dery, Elvis J. Seidu, Issah Abou, Armel N. E. Twene, Paul Tandoh, Isaac Obeng Dun-Dery, Frederick
Published in
BMC Pediatrics
Background Rotavirus is considered the main causal factor of severe gastroenteritis among infants and children globally. The association with severe rotavirus infection is mostly worse among the least developed countries, mainly due to inadequate access to medical care and poverty. This study was conducted to determine the seasonal effects in respe...
Caffarena, Rubén Darío Casaux, María Laura Schild, Carlos Omar Fraga, Martín Castells, Matías Colina, Rodney Maya, Leticia Corbellini, Luis Gustavo Riet-Correa, Franklin Giannitti, Federico
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Published in
Brazilian Journal of Microbiology
Neonatal calf diarrhea (NCD) and mortality cause significant losses to the dairy industry. The preweaning dairy calf mortality risk in Uruguay is high (15.2%); however, causes for these losses are largely unknown. This study aimed to assess whether various pathogens were associated with NCD and death in Uruguayan dairy calves and whether these infe...
Li, Yan-Dong Liu, Bao-Ning Zhao, Si-Hai Zhou, Yong-Li Bai, Liang Liu, En-Qi
Published in
World Journal of Gastroenterology
BACKGROUND Post-cholecystectomy diarrhea (PCD) frequently occurs in patients following gallbladder removal. PCD is part of the post-cholecystectomy (PC) syndrome, and is difficult to treat. After cholecystectomy, bile enters the duodenum directly, independent of the timing of meals. The interaction between the bile acids and the intestinal microbes...
Weiller, Maria Amélia Agnes Schmoeller, Evandro Vieira, Laura Valadão Barbosa, Antônio Amaral de Oliveira Feijó, Josiane Brauner, Cássio Cassal Schmitt, Eduardo Corrêa, Marcio Nunes Rabassa, Viviane Rohrig Del Pino, Francisco Augusto Burkert
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Published in
Tropical Animal Health and Production
Crossbreeding is used to increase production and disease resistance in adult animals, and there is no research to assess the performance of animals in the early stages. The aim of this study was to evaluate the zootechnical and health performance of Holstein x Gir calves (½ HG: ½ Dutch ½ Gir and ¾ HG: ¾ Dutch ¼ Gir), from birth to 80 days of age, a...
Khalilian, Alireza Ahmadimoghaddam, Davoud Saki, Shiva Mohammadi, Younes Mehrpooya, Maryam
Published in
BioPsychoSocial Medicine
BackgroundAmple evidence indicates the efficacy of serotonin type 3 (5-HT3) receptor antagonists in the treatment of patients with diarrhea-predominant irritable bowel syndrome (IBS-D). Mirtazapine is an atypical antidepressant with a well-known 5-HT3 receptor antagonist property. This study, therefore, was undertaken to investigate whether compare...
Okamoto, Akiharu Ikemura, Kenji Mizutani, Eri Iwamoto, Takuya Okuda, Masahiro
Published in
Journal of Pharmaceutical Health Care and Sciences
BackgroundThe most common adverse event (AE) associated with opioid analgesics is opioid-induced constipation (OIC). Naldemedine (NAL) is widely used for the treatment of OIC. However, diarrhea has been reported as the most common treatment-emergent AE of NAL, and little is known about the risk factors associated with the development of diarrhea du...
Laszkowska, Monika Kim, Judith Faye, Adam S. Joelson, Andrew M. Ingram, Myles Truong, Han Silver, Elisabeth R. May, Benjamin Greendyke, William G. Zucker, Jason
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Published in
Digestive Diseases and Sciences
Background Gastrointestinal symptoms are common in patients with COVID-19, but prevalence of co-infection with enteric pathogens is unknown. Aims This study assessed the prevalence of enteric infections among hospitalized patients with COVID-19. Methods We evaluated 4973 hospitalized patients ≥ 18 years of age tested for COVID-19 from March 11 thro...
Negesse, Yilkal Taddese, Asefa Adimasu Negesse, Ayenew Ayele, Tadesse Awoke
Published in
BMC Public Health
BackgroundDespite significant progress in the reduction of under-five child deaths over the last decades in Ethiopia, still diarrhea remains the second cause of morbidity and mortality among under five children next to pneumonia.ObjectiveTo show trends and determinants of diarrhea among under five children in Ethiopia based on the four Ethiopian De...
Vespa, Edoardo Pugliese, Nicola Colapietro, Francesca Aghemo, Alessio
Published in
Techniques and Innovations in Gastrointestinal Endoscopy
SARS-CoV-2 is the virus responsible for COVID-19, whose clinical spectrum ranges widely, both in terms of severity and multi-organicity. SARS-CoV-2 mainly involves the respiratory tract, causing from a flu-like syndrome to interstitial pneumonia and acute respiratory distress syndrome. Although its entry receptor, angiotensin-converting-enzyme 2, i...
