Cottin, Vincent Martinez, Fernando J. Jenkins, R. Gisli Belperio, John A. Kitamura, Hideya Molina-Molina, Maria Tschoepe, Inga Coeck, Carl Lievens, Dirk Costabel, Ulrich
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Published in
Respiratory Research
Background In the INBUILD trial in patients with progressive fibrosing interstitial lung diseases (ILDs), nintedanib reduced the rate of decline in forced vital capacity compared with placebo, with side-effects that were manageable for most patients. We used data from the INBUILD trial to characterize further the safety and tolerability of nintedan...
Nobel, Yael R Su, Steven H Anderson, Michaela R Luk, Lyndon Small-Saunders, Jennifer L Reyes-Soffer, Gissette Gallagher, Dympna Freedberg, Daniel E
Published in
Digestive diseases and sciences
Patients with SARS-CoV-2 who present with gastrointestinal symptoms have a milder clinical course than those who do not. Risk factors for severe COVID-19 disease include increased adiposity and sarcopenia. To determine whether body composition risk factors are associated with worse outcomes among patients with gastrointestinal symptoms. This was a ...
Aziz, Muhammad Haghbin, Hossein Khan, Raja Samir Khan, Zubair Weissman, Simcha Kamal, Faisal Lee-Smith, Wade Chandan, Saurabh Feuerstein, Joseph D Adler, Douglas G
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Published in
Digestive diseases and sciences
Microscopic colitis and Celiac disease have been shown to occur concomitantly, but their relationship has yet to be systematically evaluated. Some patients with refractory microscopic colitis may have simultaneous celiac disease, and the converse is also true. We performed a systematic review and meta-analysis of observational studies to assess the...
Kamboj, Amrit K McGoldrick, Jessica Voth, Eli Penrice, Daniel Tome, June Gujral, Amandeep Miller, Kaia Burke, Kristin E Pardi, Darrell S Khalili, Hamed
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Published in
Digestive diseases and sciences
Microscopic colitis (MC) primarily affects older adults; thus, data in younger patients are scarce. To compare clinical characteristics and treatment response by age at diagnosis. This retrospective cohort study was performed at Mayo Clinic and Massachusetts General Hospital. Patients were chosen consecutively using established databases. Patients ...
da Penha, Jardeliny Corrêa do Nascimento, Ludmila Alves de Sabino, Leidiane Minervina Moraes da Rocha Mendes, Elizamar Regina da Rocha, Silvana Santiago Roubert, Emilia Soares Chaves Lima, Francisca Elisângela Teixeira de Oliveira Melo, Regina Cláudia de Almeida, Paulo César Melo, Emanuella Silva Joventino
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Published in
Maternal and child health journal
Diarrhea still causes high morbidity and mortality in children under five, requiring constant interventions. Thus, the study aims to evaluate the effects of educational technologies on maternal self-efficacy to prevent childhood diarrhea. Randomized clinical trial carried out in Fortaleza, Ceará, Brazil, with four randomized groups of mothers of ch...
Li, Jiarui Cheng, Yuejuan Bai, Chunmei Xu, Jianming Shen, Lin Li, Jie Zhou, Zhiwei Li, Zhiping Chi, Yihebali Yu, Xianjun
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Published in
European journal of cancer (Oxford, England : 1990)
To investigate the health-related quality of life (HRQoL) of patients who had neuroendocrine tumors (NETs) from SANET trials. Eligible patients were randomized in a 2:1 ratio to receive surufatinib or placebo. HRQoL questionnaires, including the European Organization for Research and Treatment of Cancer QLQ-C30 and QLQ-G.I.NET21, were collected. Th...
Deutsch, David Bouchoucha, Michel Uzan, Julien Raynaud, Jean-Jacques Sabate, Jean-Marc Benamouzig, Robert
Published in
Digestive diseases and sciences
Abdominal pain is a cardinal sign of functional bowel disorders (FBD), in favor of irritable bowel syndrome (IBS). However, the determinants of abdominal pain severity (APS) are unknown. The present study aimed to search the relationships between APS and demographic, psychological, and clinical parameters in tertiary care FBD outpatients. In this r...
Wolf, Jennyfer Hubbard, Sydney Brauer, Michael Ambelu, Argaw Arnold, Benjamin F Bain, Robert Bauza, Valerie Brown, Joe Caruso, Bethany A Clasen, Thomas
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BackgroundEstimates of the effectiveness of water, sanitation, and hygiene (WASH) interventions that provide high levels of service on childhood diarrhoea are scarce. We aimed to provide up-to-date estimates on the burden of disease attributable to WASH and on the effects of different types of WASH interventions on childhood diarrhoea in low-income...
Higginson, Ellen E Sayeed, M Abu Pereira Dias, Joana Shetty, Vignesh Ballal, Mamatha Srivastava, Sunil Kumar Willis, Ian Qadri, Firdausi Dougan, Gordon Mutreja, Ankur
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Enterotoxigenic Escherichia coli (ETEC) is an important cause of diarrhea in children in low- and middle-income countries (LMICs). However, large-scale pathogen burden studies in children have identified ETEC in the guts of both symptomatic patients and controls. The factors that influence this balance are poorly understood, but it is postulated th...
Yan, Zunxiang Zhang, Kai Zhang, Kang Wang, Guibo Wang, Lei Zhang, Jingyan Qiu, Zhengying Guo, Zhiting Kang, Yandong Song, Xiaoping
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Published in
Journal of ethnopharmacology
Huang Bai Jian Pi (HBJP) decoction, a Chinese herbal formula based on the Pulsatilla decoction (PD) and Si Junzi decoction, is efficacy to treat clinical diarrhea in calves. The mechanism of HBJP decoction to treat calf diarrhea remains unclear. This study was to investigate the therapeutic effect and anti-inflammatory mechanism of HBJP decoction o...
