Scorcia, Vincenzo Giannaccare, Giuseppe Gatti, Valentina Vaccaro, Sabrina Piccoli, Gabriele Villì, Annarita Toro, Mario Damiano Yu, Angeli Christy Iovino, Claudio Simonelli, Francesca
...
Published in
Ophthalmology and Therapy
Introduction To compare the functional and anatomic outcomes between eyes in patients with diabetic macular edema (DME) who underwent a complete anti-vascular endothelial growth factor (VEGF) loading dose with aflibercept and those who were switched to dexamethasone intravitreal (DEX) implant after an incomplete anti-VEGF treatment regimen during t...
Özsaygili, Cemal Küçük, Bekir Yildirim, Yener
Published in
The British journal of ophthalmology
To investigate the effect of posterior vitreous detachment (PVD) on aflibercept response in treatment-naïve diabetic macular oedema (DME). A retrospective cohort study. One hundred and fifty eyes of 150 treatment-naïve patients with DME were enrolled. The patients were divided into three groups according to their PVD status: group 1 (no PVD during ...
Beatson, Bradley Arevalo, J. Fernando
Published in
Journal of Ophthalmic & Vision Research
The off-label, therapeutic use of intravitreal bevacizumab (IVB) in vascular retinal diseases such as diabetic macular edema and proliferative diabetic retinopathy (PDR) has increased significantly due to its ability to reduce retinal neovascularization and slow progression of disease. Here, we will review the literature and investigative developme...
Karimi, Saeed Movafaghi, Vahid Arabi, Amir Shahraki, Toktam Safi, Sare
Published in
Journal of Ophthalmic & Vision Research
Purpose To assess the effects of oral vitamin D supplement therapy on clinical outcomes of intravitreal bevacizumab (IVB) injections in patients with diabetic macular edema (DME). Methods Seventy-one patients with center-involving DME received IVB injections three times monthly. Cases with serum 25-hydroxyvitamin D (25(OH)D) levels
Mirshahi, Ahmad Lashay, Alireza Riazi-Esfahani, Hamid Ebrahimiadib, Nazanin Khojasteh, Hassan Ghassemi, Fariba Bazvand, Fatemeh Khodabande, Alireza Roohipour, Ramak Pour, Elias Khalili
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Published in
Journal of Ophthalmic & Vision Research
Purpose To report the results of intravitreal injection of a bevacizumab biosimilar called StivantⓇ Methods This prospective interventional case series was conducted on eyes with neovascular age-related macular degeneration (nAMD), retinal vein occlusion (RVO), and diabetic macular edema (DME). StivantⓇ was injected in three consecutive months and ...
Mohamadpour, Mehrdad Khorrami-Nejad, Masoud Kiarudi, Mohammad Yaser Khosravi, Keivan
Published in
Journal of Ophthalmic & Vision Research
Purpose To evaluate the ectasia risk score system in cancelled laser in situ keratomileusis (LASIK) candidates at an academic hospital. Methods LASIK candidates who had been cancelled by a surgeon considering the patient age, preoperative central corneal thickness, residual stromal bed thickness, or preoperative manifest refraction spherical equiva...
Maleki, Arash Stephenson, Andrew Phillips Hajizadeh, Fedra
Published in
Journal of Ophthalmic & Vision Research
Purpose To report the efficacy of topical interferon alpha 2b in the treatment of refractory diabetic macular edema. Methods In this retrospective interventional case series, five eyes of three individuals with diabetic macular edema resistant to multiple intravitreal injections of anti-vascular endothelial growth factor drugs and macular photocoag...
Furino, Claudio Niro, Alfredo Reibaldi, Michele Boscia, Francesco Alessio, Giovanni
Published in
Journal of Ophthalmic & Vision Research
Purpose Different patterns of diabetic macular edema (DME) suggest different pathogenesis and drug response. We evaluated the outcomes after intravitreal dexamethasone (DEX) implant for DME with or without serous retinal detachment (SRD). Methods In this retrospective study, 22 naïve patients (23 eyes) with DME who underwent a single DEX implant we...
Grieco, Giuseppina Emanuela Sebastiani, Guido Eandi, Chiara Maria Neri, Giovanni Nigi, Laura Brusco, Noemi D’Aurizio, Romina Posarelli, Matteo Bacci, Tommaso De Benedetto, Elena
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Published in
International Journal of Molecular Sciences
We identified and compared secreted microRNA (miRNA) expression in aqueous humor (AH) and plasma samples among patients with: type 2 diabetes mellitus (T2D) complicated by non-proliferative diabetic retinopathy (DR) associated with diabetic macular edema (DME) (DME group: 12 patients); T2D patients without DR (D group: 8 patients); and non-diabetic...
Guliani, Brahm Prakash Agarwal, Isha Naik, Mayuresh P.
Published in
Journal of Ophthalmic & Vision Research
Purpose To assess the quantitative changes of macula in diabetic and non-diabetic eyes after uncomplicated cataract surgery. Methods In this prospective interventional study being performed in a tertiary healthcare hospital, a total of 660 eyes were divided into two groups. Group 1 included 330 eyes from healthy subjects and group 2 included 330 ey...
