Influence of Human Serum Albumin Glycation on the Binding Affinities for Natural Flavonoids
Published in Open Chemistry
The impact of body weight and diabetes on new-onset atrial fibrillation: a nationwide population based study
...Published in Cardiovascular Diabetology
BackgroundBeing obese or underweight, and having diabetes are important risk factors for new-onset atrial fibrillation (AF). However, it is unclear whether there is any interaction between body weight and diabetes in regard to development of new-onset AF. We aimed to evaluate the role of body weight status and various stage of diabetes on new-onset...
Disease–treatment interactions in the management of patients with obesity and diabetes who have atrial fibrillation: the...
Published in Cardiovascular Diabetology
Both obesity and type 2 diabetes are important risk factors for atrial fibrillation (AF), possibly because they both cause an expansion of epicardial adipose tissue, which is the source of proinflammatory adipocytokines that can lead to microvascular dysfunction and fibrosis of the underlying myocardium. If the derangement of epicardial fat adjoins...
Generation of insulin-secreting cells from mouse gallbladder stem cells by small molecules in vitro
...Published in Stem Cell Research & Therapy
BackgroundStem cell-derived pancreatic β-like cells hold great promise for treating diabetes. Gallbladder belongs to the extrahepatic bile duct system and possesses stem-like cells. These stem cells could be expanded in vitro and have the potential of differentiating into hepatocytes, cholangiocytes, or pancreatic cells. As the gallbladder is highl...
Aspirin for Primary Prevention of Cardiovascular Disease in Diabetes: a Review of the Evidence
Published in Current Diabetes Reports
Purpose of ReviewPeople with diabetes are at a higher risk of atherosclerotic cardiovascular disease (ASCVD) compared with those without diabetes. Though aspirin has been shown to have an overall net clinical benefit when used for secondary prevention of ASCVD in people with and without diabetes, the evidence for primary prevention, especially in t...
Herbal or traditional medicine consumption in a Thai worker population: pattern of use and therapeutic control in chroni...
Published in BMC Complementary and Alternative Medicine
BackgroundHerbal and traditional medicines (HTM) are widely used in Asian countries. Specific data on prevalent of HTM usage and association with chronic diseases in the Thai population is currently lacking. We examined the prevalence and factors associated with HTM use in a Thai worker population. In addition, we explored the relationship between ...
Long-term statin persistence is poor among high-risk patients with dyslipidemia: a real-world administrative claims anal...
Published in Lipids in Health and Disease
BackgroundA decade ago, statin persistence was 40 mg/dL (n = 23,181). Both cohorts were followed for ≥ 6 months up to March 2016.ResultsThe probability of remaining on a prescription fill for index statin therapy was 47% after 1 year and 19% after 5 years in both cohorts. Statin persistence was worse among women than men, and among younger versus ...
Prevalence of dental caries in children and adolescents with type 1 diabetes: a systematic review and meta-analysis
Published in BMC Oral Health
BackgroundDental caries and type 1 diabetes are responsible for a large burden of global disease; however, the exact prevalence of dental caries among children and adolescents with type 1 diabetes remains controversial, and no quantitative meta-analysis exists. Thus, we performed a meta-analysis to evaluate the prevalence of dental caries among chi...
Service evaluation of diabetes management during pregnancy in a regional maternity hospital: potential scope for increas...
...Published in BMC Health Services Research
BackgroundPre-gestational and gestational diabetes mellitus are common complications in pregnancy affecting one in six pregnancies. The maternity services are under significant strain managing the increasing number of complex pregnancies. This has an impact on patients’ experience of antenatal care. Therefore, there is a clear need to address pregn...
Inpatient Diabetes Education in the Real World: an Overview of Guidelines and Delivery Models
Published in Current Diabetes Reports
Purpose of ReviewDiabetes self-management education and support improves diabetes-related outcomes, yet less than 50% of persons with diabetes in the USA receive this service. Hospital admissions present a critical opportunity for providing diabetes education. This article presents an overview of the current state of inpatient diabetes education. I...
