Design of a comprehensive microfluidic and microscopic toolbox for the ultra-wide spatio-temporal study of plant protopl...
International audience
Development and evaluation of an application for syphilis control
ABSTRACT Objective: to develop and evaluate an application for syphilis control in pregnant women. Method: methodological research developed between March and November of 2016 in two phases: bibliographic survey of the years 2012 to 2016 in the databases PubMed, CAPES and Scopus and application development. Eight users participated in the usability...
Chest circumference in full-term newborns: how can it be predicted?
Published in BMC Pediatrics
BackgroundAlthough over the years a number of studies have used chest circumference (CC) as a sensitive tool to identify the health status of infants, a particularly important aspect for this population is the lack of data on normal values and prediction equations. In order to facilitate and validate the interpretation of CC data in newborn (NB), t...
Issues of the Arctic development in the Far East (Russia)
The development of the Arctic and Subarctic Far East territories is one of the key-issues for the Russian Federation and the regional authorities to generate economic and social take-off for the populations in these arctic and subarctic regions. The problematic is even more delicate in such territories as Yakutia for example. They both concentrate ...
Further clarification on permissive and instructive causes
Published in Biology & Philosophy
I respond to recent criticism of my analysis of the permissive-instructive distinction and outline problems with the alternative analysis on offer. Amongst other problems, I argue that the use of formal measures is unclear and unmotivated, that the distinction is conflated with others that are not equivalent, and that no good reasons are provided f...
“Too much guts and not enough brains”: (epi)genetic mechanisms and future therapies of Hirschsprung disease — a review
Published in Clinical Epigenetics
Hirschsprung disease is a neurocristopathy, characterized by aganglionosis in the distal bowel. It is caused by failure of the enteric nervous system progenitors to migrate, proliferate, and differentiate in the gut. Development of an enteric nervous system is a tightly regulated process. Both the neural crest cells and the surrounding environment ...
Effect of soil disturbance by agricultural activities on the life history traits of monkey frog (Pithecopus azureus)
Published in Environmental Monitoring and Assessment
We assessed whether soil disturbance by agricultural activity influences the growth, development, and survival of individuals in the larval, metamorphic, and postmetamorphic stages of amphibians. Tadpoles of Pithecopus azureus (Cope, 1862) were reared in microcosms assembled with soil from two sites, a pristine site and a rice field. For 5 weeks, w...
Does the fortified milk with high iron dose improve the neurodevelopment of healthy infants? Randomized controlled trial...
...Published in BMC Pediatrics
BackgroundSince iron plays an important role in several physiological processes, its deficiency but also overload may harm the development of children. The aim was to assess the effect of iron–fortified milk on the iron biochemical status and the neurodevelopment of children at 12 months of age.MethodsRandomized controlled trial conducted in 133 Sp...
Function and mechanism of long non-coding RNA Gm21284 in the development of hippocampal cholinergic neurons
Published in Cell & Bioscience
BackgroundIncreasing evidence has revealed that long non-coding RNAs (lncRNAs) play a pivotal role in the development of nervous system. Our previous studies have demonstrated that enhanced cholinergic neurogenesis occurs in the subgranular zone (SGZ) of the hippocampal dentate gyrus (DG) after cholinergic denervation, which is closely associated w...
Efficient derivation of knock-out and knock-in rats using embryos obtained by in vitro fertilization
Rats are effective model animals and have contributed to the development of human medicine and basic research. However, the application of reproductive engineering techniques to rats is not as advanced compared with mice, and genome editing in rats has not been achieved using embryos obtained by in vitro fertilization (IVF). In this study, we condu...
