Published in Nature Communications
Mitochondria produce high amounts of ATP to power myosin motors and sustained muscle contraction. Here, the authors show that during development, muscles coordinate the morphogenesis of their myofibrils directly with their mitochondria to optimize both for the physiological needs of each muscle-type.
This real property development project walked through the steps and procedures that are typical for real property development. The project focused on a conceptual multi-unit student housing project located near Cal Polys campus. The rental market in San Luis Obispo is very competitive and through market and financial analysis, it was determined tha...
Cajal-Retzius neurons (CRs) are among the first-born neurons in the developing cortex of reptiles, birds and mammals, including humans. CRs' peculiarity lies in the fact they are initially embedded into the immature neuronal network before being almost completely eliminated by cell death at the end of cortical development. CRs are best known for co...
The purpose of this project was to establish a chapter of Engineers in Action at California Polytechnic State University in San Luis Obispo. Engineers in Action is a non-profit organization which is dedicated to constructing footbridges in underserved countries. Bridges are linked to many benefits for those without reliable access year-round. Chapt...
Published in Nutritional neuroscience
Background: Previous studies on preclinical models have shown that giving supplemental choline during the embryonic period improves performance on memory tasks during adulthood. However, the effects of an early intervention on the development of cognitive functions in the immature brain have not been widely studied. In addition, it has been well es...
Computer-Aided Software Engineering (CASE) tools are popular software programs to support the members of the development team (including analysts, designers, coders, database administrators, and project managers) in building new software systems. Up-to-date and consistent knowledge representation and documentation is crucial for companies developin...
This case study investigates low-income housing and why it can be more difficult to build compared to other construction projects. Five individuals of PREMIER Design + Build Group were interviewed and gave their opinions on the subject. Each person interviewed has a different role in the company a market leader, project manager, superintendent, and...
Published in Journal of developmental origins of health and disease
The Developmental Origins of Health and Disease (DOHaD) framework aims to understand how environmental exposures in early life shape lifecycle health. Our understanding and the ability to prevent poor health outcomes and enrich for resiliency remain limited, in part, because exposure-outcome relationships are complex and poorly defined. We, therefo...
Published in Journal of Inflammation
BackgroundAnti-vascular endothelial growth factor (VEGF) has been used as a therapeutic drug for the treatment of some human diseases. However, no systematic evidence is performed for assessing the role of VEGF in periodontitis. We carried out a comprehensive analysis to explore the role of VEGF in patients with periodontitis.MethodsMultiple databa...
Published in Environmental Health and Preventive Medicine
BackgroundThe Hokkaido Study on Environment and Children’s Health is an ongoing study consisting of two birth cohorts of different population sizes: the Sapporo cohort and the Hokkaido cohort. Our primary objectives are to (1) examine the effects that low-level environmental chemical exposures have on birth outcomes, including birth defects and gro...
