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Reasons for Being "Zero-Dose and Under-Vaccinated" among Children Aged 12-23 Months in the Democratic Republic of the Co...

Published in Vaccines

(1) Introduction: The Democratic Republic of the Congo (DRC) has one of the largest cohorts of un- and under-vaccinated children worldwide. This study aimed to identify and compare the main reasons for there being zero-dose (ZD) or under-vaccinated children in the DRC. (2) Methods: This is a secondary analysis derived from a province-level vaccinat...

Polymeric-Micelle-Based Delivery Systems for Nucleic Acids.

Published in Pharmaceutics

Nucleic acids can modulate gene expression specifically. They are increasingly being utilized and show huge potential for the prevention or treatment of various diseases. However, the clinical translation of nucleic acids faces many challenges due to their rapid clearance after administration, low stability in physiological fluids and limited cellu...

Quantum Lernmatrix.

Published in Entropy (Basel, Switzerland)

We introduce a quantum Lernmatrix based on the Monte Carlo Lernmatrix in which n units are stored in the quantum superposition of log2(n) units representing On2log(n)2 binary sparse coded patterns. During the retrieval phase, quantum counting of ones based on Euler's formula is used for the pattern recovery as proposed by Trugenberger. We demonstra...

Vaccine-derived poliovirus serotype 2 outbreaks and response in the Democratic Republic of the Congo, 2017-2021.

Published in Vaccine

Vaccine-derived polioviruses (VDPVs) can emerge from Sabin strain poliovirus serotypes 1, 2, and 3 contained in oral poliovirus vaccine (OPV) after prolonged person-to-person transmission where population vaccination immunity against polioviruses is suboptimal. VDPVs can cause paralysis indistinguishable from wild polioviruses and outbreaks when co...

A Successful National and Multipartner Approach to Increase Immunization Coverage: The Democratic Republic of Congo Mash...

BackgroundThe immunization system in the Democratic Republic of the Congo faces many challenges, including persistent large-scale outbreaks of polio, measles, and yellow fever; a large number of unvaccinated children for all antigens; minimal and delayed funding; and poor use of immunization data at all levels. In response, the Expanded Programme o...

Reported History of Measles and Long-term Impact on Tetanus Antibody Detected in Children 9-59 Months of Age and Receivi...

BackgroundRecent studies suggest measles-induced immune amnesia could have long-term immunosuppressive effects via preferential depletion of memory CD150+ lymphocytes, and associations with a 2-3 year period of increased mortality and morbidity from infectious diseases other than measles has been shown in children from wealthy and low-income countr...

Contesting the crisis narrative: epidemic accounts in Sierra Leone, Tanzania, and Democratic Republic of the Congo.

Published in Disasters

在COVID-19大流行的最初几个月，科学家和全球评论员密切关注非洲国家，预测一场灾难即将来临，因为他们认为病毒将让本已薄弱的卫生系统全面崩溃。这些预测源自于想象非洲不可避免地成为流行病灾难的重灾区。本文借用坦桑尼亚、塞拉利昂和刚果民主共和国的案例，将全球灾难框架与危机和危机管理的日常想象和危机经验及管理进行对比。我们利用人种学研究，探讨了如何理解COVID-19与以前的流行病（从艾滋病到埃博拉病毒）以及政治冲突的关系。然后，我们分析了全球危机叙述如何与日常的集体和个人经历产生联系，并与之产生紧张关系。本文将这些经验性反思与围绕危机的话语建构及其影响的理论辩论对话，并认为这些紧张关系很重要，因为危机框架会产生后果。 关键词：非洲；灾难；Covid-19；危机；民主刚果；流行病；人种学；健康；...

Impact of an Emergency Strategy to Revitalize the Routine Immunization System of the Democratic Republic of the Congo, t...

Background: Vaccines have been a major medical achievement in modern history, significantly reducing the spread of infectious diseases worldwide. Routine immunization (RI) systems have become a global standard for providing consistent access to vaccination services and protecting communities against vaccine-preventable diseases. The Democratic Repu...