Kinganda-Lusamaki, Eddy; Amuri-Aziza, Adrienne; Fernandez-Nuñez, Nicolas; Makangara-Cigolo, Jean-Claude; Pratt, Catherine; Vakaniaki, Emmanuel Hasivirwe; Hoff, Nicole A.; Luakanda-Ndelemo, Gradi; Akil-Bandali, Prince; Nundu, Sabin Sabiti;
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Recent reports raise concerns on the changing epidemiology of mpox in the Democratic Republic of the Congo (DRC). High-quality genomes were generated for 337 patients from 14/26 provinces to document whether the increase in number of cases is due to zoonotic spillover events or viral evolution, with enrichment of APOBEC3 mutations linked to human a...
Vakaniaki, Emmanuel Kacita, Cris Kinganda-Lusamaki, Eddy OToole, Áine Wawina-Bokalanga, Tony Mukadi-Bamuleka, Daniel Amuri-Aziza, Adrienne Malyamungu-Bubala, Nadine Mweshi-Kumbana, Franklin Mutimbwa-Mambo, Léandre
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Outbreaks of monkeypox (mpox) have historically resulted from zoonotic spillover of clade I monkeypox virus (MPXV) in Central Africa and clade II MPXV in West Africa. In 2022, subclade IIb caused a global epidemic linked to transmission through sexual contact. Here we describe the epidemiological and genomic features of an mpox outbreak in a mining...
Vakaniaki, Emmanuel Hasivirwe; Kinganda-Lusamaki, Eddy; Merritt, Sydney; Kasongo, Francois; Malembi, Emile; Lunyanga, Lygie; Linsuke, Sylvie; Halbrook, Megan; Kalthan, Ernest; Pukuta, Elisabeth;
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We linked 4 mpox cases in South Ubangi, Democratic Republic of the Congo, to transboundary transmission from Central African Republic. Viral genome sequencing demonstrated that the monkeypox virus sequences belonged to distinct clusters of subclade Ia. This finding demonstrates the borderless nature of mpox and highlights the need for vigilant regi...
Guyeux, Christophe Senelle, Gaetan Le Meur, Adrien Supply, Philip Gaudin, Cyril Rigouts, Leen de Jong, Bouke Sola, Christophe Refrégier, Guislaine
International audience
Vakaniaki, Emmanuel Kinganda-Lusamaki, Eddy Merritt, Sydney Kasongo, Francois Malembi, Emile Lunyanga, Lygie Linsuke, Sylvie Halbrook, Megan Kalthan, Ernest Pukuta, Elisabeth
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We linked 4 mpox cases in South Ubangi, Democratic Republic of the Congo, to transboundary transmission from Central African Republic. Viral genome sequencing demonstrated that the monkeypox virus sequences belonged to distinct clusters of subclade Ia. This finding demonstrates the borderless nature of mpox and highlights the need for vigilant regi...
St Louis, Patricia Makali, Samuel Lwamushi Paul, Elisabeth
peer reviewed
Oleffe, Amandine Paul, Elisabeth Mahieu, Céline
peer reviewed / BACKGROUND: Medicine retailers, considered here as any person or setting dedicated to the sale of retail medicines, fill an important gap in terms of access to healthcare in areas where population are not covered by universal healthcare schemes. In Goma in the Democratic Republic of the Congo, such retailers have proliferated and ar...
Wawina-Bokalanga, Tony; Akil-Bandali, Prince; Kinganda-Lusamaki, Eddy; Lokilo, Emmanuel; Jansen, Daan; Amuri-Aziza, Adrienne; Makangara-Cigolo, Jean-Claude; Pukuta-Simbu, Elisabeth; Ola-Mpumbe, Rilia; Muyembe, Mamito;
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Between January and August 2024, mpox cases have been reported in nearly all provinces of the Democratic Republic of the Congo (DRC). Monkeypox virus genome sequences were obtained from 11 mpox cases' samples, collected in July-August 2024 in several health zones of Kinshasa. Characterisation of the sequences showed subclades Ia and Ib co-circulati...
angendu, karl b. akilimali, pierre z. tran, nguyen toan magne, julien
Introduction: The Democratic Republic of Congo (DRC) does not have national prevalence data for arterial hypertension (HTN) or diabetes (type I and II combined) to aid evidence-based decision-making, despite the assumption of epidemiological transition in low- and middle-income countries. The aim of this study was to estimate a proxy of prevalence ...
Mondo, Jean M Chuma Basimine, Géant Matiti, Henri M Kihye, Jacques B Bagula, Espoir M Karume, Katcho Kahindo, Charles Egeru, Anthony Majaliwa, Jackson-Gilbert M Agre, Paterne A
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peer reviewed / The traditional crop calendar for yam (Dioscorea spp.) in South-Kivu, eastern Democratic Republic of Congo (DRC), is becoming increasingly inadequate given the significant climatic variability observed over the last three decades. This study aimed at: (i) assessing trends in weather data across time and space to ascertain climate ch...