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Stress-induced cellular responses in immunogenic cell death: Implications for cancer immunotherapy

Published in Biochemical Pharmacology

Cancer is evading the host's defense mechanisms leading to avoidance of immune destruction. During tumor progression, immune-evading cancer cells arise due to selective pressure from the hypoxic and nutrient-deprived microenvironment. Thus, therapies aiming at re-establishing immune destruction of pathological cells constitute innovating anti-cance...