Ugwu, Emmanuel O Eleje, George U Ugwu, Angela O Nwagha, Uchenna I Ikechebelu, Joseph I Umeh, Uchenna A Okafor, Henrietta U
Published in
The Cochrane database of systematic reviews
Hepatitis B virus (HBV)-human Immunodeficiency virus (HIV) co-infection promotes an aggressive disease course of HBV infection. In the only available non-Cochrane systematic review on antiviral therapy during pregnancy for prevention of mother-to-child transmission of HBV, none of the women studied had HBV-HIV co-infection but were either HBV- or H...
Hawkins, Dorothy EDP Bayfield, Oliver W Fung, Herman KH Grba, Daniel N Huet, Alexis Conway, James F Antson, Alfred A
Acknowledgements: The authors would like to thank J. Turkenburg, S. Hart and J.N. Blaza for assistance in cryo-electron microscopy at York and K.L. Morris for data collection assistance at eBIC, M. Chechik for assistance in protein production and Hesketh E.L., Thompson R.F. and Maskell D.P. for collection of additional data sets and help with proce...
Hawkins, Dorothy EDP Bayfield, Oliver W Fung, Herman KH Grba, Daniel N Huet, Alexis Conway, James F Antson, Alfred A
Acknowledgements: The authors would like to thank J. Turkenburg, S. Hart and J.N. Blaza for assistance in cryo-electron microscopy at York and K.L. Morris for data collection assistance at eBIC, M. Chechik for assistance in protein production and Hesketh E.L., Thompson R.F. and Maskell D.P. for collection of additional data sets and help with proce...
Allain, Jean-Pierre Owusu-Ofori, Shirley Ye, Xianlin Bisseye, Cyrille Chaar, Mira El Li, Chengyao
Immune control of various infectious diseases, particularly viral, was shown to be more efficient for females than males. Response to viral vaccines (HAV, HBV) was higher in females. Data on hepatitis B virus (HBV) markers accumulated over 15 years in blood donors was stratified according to sex, including HBsAg, HBV viral load and levels of anti-H...
Deng, Xuelian Guo, Xiaohan Gu, Hongfang Wang, Dong Laperche, Syria Allain, Jean-Pierre Zang, Liang Candotti, Daniel
Funder: Grifols Diagnostic Solutions Inc / Absence of anti-HBc reactivity with detectable anti-HBs was observed in blood donors with occult hepatitis B virus (HBV) infection (OBI). The prevalence and mechanisms underlying this uncommon condition were investigated over time in Chinese blood donors with OBI. Isolated anti-HBs OBI status was identifie...
Farrell, PJ White, RE
Most of the world’s population is infected by the Epstein–Barr virus (EBV), but the incidence of the diseases associated with EBV infection differs greatly in different parts of the world. Many factors may determine those differences, but variation in the virus genome is likely to be a contributing factor for some of the diseases. Here, we describe...
Álvarez, Eva G Demeulemeester, Jonas Otero, Paula Jolly, Clemency García-Souto, Daniel Pequeño-Valtierra, Ana Zamora, Jorge Tojo, Marta Temes, Javier Baez-Ortega, Adrian
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Most cancers are characterized by the somatic acquisition of genomic rearrangements during tumour evolution that eventually drive the oncogenesis. Here, using multiplatform sequencing technologies, we identify and characterize a remarkable mutational mechanism in human hepatocellular carcinoma caused by Hepatitis B virus, by which DNA molecules fro...
Payne, H Chan, MK Watters, SA Otwombe, K Hsiao, N-Y Babiker, A Violari, A Cotton, MF Gibb, DM Klein, NJ
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Background Reduction of the reservoir of latent HIV-infected cells might increase the possibility of long-term remission in individuals living with HIV. We investigated factors associated with HIV-1 proviral DNA levels in children receiving different antiretroviral therapy (ART) strategies in the children with HIV early antiretroviral therapy (CHER...
Brendle, Sarah Li, Jingwei J Cladel, Nancy M Shearer, Debra A Budgeon, Lynn R Balogh, Karla K Atkins, Hannah Costa-Fujishima, Marina Lopez, Paul Christensen, Neil D
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Papillomavirus L1 and L2, the major and minor capsid proteins, play significant roles in viral assembly, entry, and propagation. In the current study, we investigate the impact of L1 and L2 on viral life cycle and tumor growth with a newly established mouse papillomavirus (MmuPV1) infection model. MmuPV1 L1 knockout, L2 knockout, and L1 plus L2 kno...
Pasternak, AO Vroom, J Kootstra, NA Wit, FWNM De Bruin, M De Francesco, D Bakker, M Sabin, CA Winston, A Prins, JM
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Background: It remains unclear whether combination antiretroviral therapy (ART) regimens differ in their ability to fully suppress human immunodeficiency virus (HIV) replication. Here, we report the results of two cross-sectional studies that compared levels of cell-associated (CA) HIV markers between individuals receiving suppressive ART containin...
