Ribeiro Guerra, Maximiliano Coignard, Juliette Eon-Marchais, Séverine Dondon, Marie-Gabrielle Le Gal, Dorothée Beauvallet, Juana Mebirouk, Noura Belotti, Muriel Caron, Olivier Gauthier-Villars, Marion
...
Published in
Breast Cancer Research
BackgroundDiagnostic ionizing radiation is a risk factor for breast cancer (BC). BC risk increases with increased dose to the chest and decreases with increased age at exposure, with possible effect modification related to familial or genetic predisposition. While chest X-rays increase the BC risk of BRCA1/2 mutation carriers compared to non-carrie...
Lerebours, Adélaïde Murzina, Svetlana Song, You Tollefsen, Knut Erik Benedetti, Maura Regoli, Francesco Rotchell, Jeanette M Nahrgang, Jasmine
Published in
Marine environmental research
Studies that aim to characterise the susceptibility of the ecologically relevant and non-model fish polar cod (Boreogadus saida) to model carcinogens are required. Polar cod were exposed under laboratory conditions for six months to control, 0.03 μg BaP/g fish/week and 0.3 μg BaP/g fish/week dietary benzo(a)pyrene (BaP), a reference carcinogen. The...
Panjali, Zahra Hahad, Omar Rajabi, Fatemeh Maddah, Saeid Zendehdel, Rezvan
Published in
Toxicology and industrial health
Foundry workers are exposed to numerous occupational health hazards, which may result in increased risk of cancer, respiratory disease, and other diseases. Oxidative stress is known to be involved in the pathogenesis of such diseases. The present study aimed to investigate the association between multiple occupational exposures in foundry workers a...
Li, Jiayin Zhou, Jingxu Zhang, Jing Xiao, Zhiwei Wang, Wenping Chen, Hanrui Lin, Lizhu Yang, Qiuye
Published in
Journal of thoracic disease
Lung adenocarcinoma (LUAD) is the most common type of lung cancer. DNA repair genes (DRGs) is important in lung cancer. The relationship between the immune environment and the expression levels of DRGs in LUAD remains unclear. The purpose of this study is to assess the relationship between DRGs and the immune environment and clinical characteristic...
Kivanc, Demet Dasdemir, Selcuk
Published in
Rheumatology international
Tissue inflammation and damage with the abnormal and overactivation of innate immune system results with the development of a hereditary disease group of autoinflammatory diseases. Multiple numbers of DNA damage develop with the continuous exposure to endogenous and exogenous genotoxic effects, and these damages are repaired through the DNA damage ...
Gupta, Ankita Mathew, Don Bhat, Shabir Ahmad Ghoshal, Sushmita Pal, Arnab
Published in
Frontiers in Oncology
Purpose To investigate the impact of genetic variants of DNA repair and pro-fibrotic pathway genes on the severity of radiation-induced subcutaneous fibrosis in patients of oropharyngeal carcinoma treated with radical radiotherapy. Materials and Methods Patients of newly diagnosed squamous cell carcinoma of oropharynx being treated with two-dimensi...
Silva, Susana Nunes Gomes, Bruno Costa André, Saudade Félix, Ana Rodrigues, António Sebastião Rueff, José
Published in
Breast Cancer Research and Treatment
Background Breast cancer (BC) is the most common cancer in women. In contrast, male BC is about 100 times less common than in women, being considered a rare disease. Male BC may be a distinctive subtype of BC and available data seems to indicate that male BC has a higher dependence on genetic variants than female BC. Nevertheless, the same prognost...
Chen, Minjie Dong, Hui Deng, Shengchang Zhou, Ying
Published in
American Journal of Translational Research
DNA repair-related genes (DRGs) have attracted much attention in the field of oncology. However, the prognostic role of DRGs and their biological function in lung adenocarcinoma (LUAD) remains rudimentary and inconclusive. In this study, 716 LUAD cases from two different cohorts were collected. Samples from The Cancer Genome Atlas (TCGA) were used ...
Ozdilli, Kursat Pehlivan, Mustafa Serin, Istemi Savran, Fatma Oguz Tomatir, Ayse Gaye Pehlivan, Sacide
Published in
Mediterranean Journal of Hematology and Infectious Diseases
Costa, Marilia Braga Farias, Izabelle Rocha da Silva Monte, Cristiane Filho, Luiz Ivando Pires Ferreira de Paula Borges, Daniela de Oliveira, Roberta Taiane Germano Ribeiro-Junior, Howard Lopes Magalhães, Silvia Maria Meira Pinheiro, Ronald Feitosa
Published in
Environmental toxicology and pharmacology
Exposure to pesticides is considered a major factor underlying increased risk of hematological disorders in agricultural workers due to its carcinogenic potential. However, genotoxic impact of pesticides in DNA integrity of bone marrow stem cells (BMSC) of farmers exposed is not yet well known. We evaluated presence of chromosomal abnormalities (CA...
