Cet article s’intéresse à la sensibilité de la demande de prise en charge de la perte d’autonomie vis-à-vis de l’offre. En nous appuyant sur un modèle théorique, nous estimons la probabilité de choisir un mode de prise en charge grâce à une modélisation multinomiale utilisant les données des enquêtes CARE (Capacités, aides et ressources des seniors...
Most genes associated with neurodevelopmental disorders (NDDs) were identified with an excess of de novo mutations (DNMs) but the significance in case-control mutation burden analysis is unestablished. Here, we sequence 63 genes in 16,294 NDD cases and an additional 62 genes in 6,211 NDD cases. By combining these with published data, we assess a to...
Published in Health technology assessment (Winchester, England)
The aim of this study was to find out the benefits and costs of providing very young children, aged
Published in Neuropsychological rehabilitation
After an acquired brain injury (ABI), the achievement of previous life goals may no longer be feasible. This study examined whether self-reported disengagement from previous goals and reengagement towards new, more feasible goals, are associated with higher quality of life (QOL) and life satisfaction. We also examined whether acceptance mediated th...
En 1851, une variable relative aux infirmités est introduite dans le recensement français. Jusqu’en 1876, les individus atteints de folie, de la perte d’un sens (vue, ouïe, parole) ou de goitre sont dénombrés lors de ces opérations quinquennales. En parallèle, des comptes rendus sur le recrutement militaire font état des jeunes hommes impropres à p...
Published in Genes
Human pathogenic variants of TBC1D24 are associated with clinically heterogeneous phenotypes, including recessive nonsyndromic deafness DFNB86, dominant nonsyndromic deafness DFNA65, seizure accompanied by deafness, a variety of isolated seizure phenotypes and DOORS syndrome, characterized by deafness, onychodystrophy, osteodystrophy, intellectual ...
Published in JBMR plus
Age-related bone loss is common in older adults. However, the association of low bone mass with incident disability and mortality is not well established. A sample of 738 participants in the Rush Memory and Aging Project (MAP) was evaluated at baseline for bone mineral density (BMD) using quantitative ultrasound at the calcaneus. An annual intervie...
Background The Global Burden of Disease (GBD) study establishes headache as the second-highest cause of disability worldwide. Because most headache data in GBD are from adults, leading to underestimation of headache-attributed burden, a global schools-based programme within the Global Campaign against Headache is contributing data from children (7–...
Background The Global Campaign against Headache collects data from children (7–11 years) and adolescents (12–17 years) both to inform health and education policies and to contribute to the Global Burden of Disease (GBD) study. This survey in Mongolia was part of this global enquiry. Methods Following the generic protocol for the global enquiry, thi...
Background: Many of the painful, disabling features of early diffuse cutaneous systemic sclerosis have an inflammatory component and are potentially treatable with corticosteroid therapy. These features include painful and itchy skin, fatigue and musculoskeletal involvement. Yet many clinicians are understandably reluctant to prescribe corticostero...
