Liu, Binjie Zhang, Shanshan Sun, Lizhu Huang, Lan Zhang, Rong Liu, Zhongqiu An, Lin
Published in
International journal of molecular sciences
Psychological distress is associated with an increase in liver disease mortality. This association highlights the close relationship between psychological and physical health. The underlying mechanism of this association needs to be elucidated. In this study, a rat model of anxiety was developed via compound stress. Changes in the HPA axis and infl...
Adebayo, Oyindamola C.C.; 134542; Nkoy, Agathe B.B.; van den Heuvel, Lambertus P.P.; Labarque, Veerle; 41869; Levtchenko, Elena; 55533; Delanaye, Pierre; Pottel, Hans; 3149;
Glomerular hyperfiltration (GHF) is a phenomenon that can occur in various clinical conditions affecting the kidneys such as sickle cell disease, diabetes mellitus, autosomal dominant polycystic kidney disease, and solitary functioning kidney. Yet, the pathophysiological mechanisms vary from one disease to another and are not well understood. More ...
Dachy, Angelique; 137673; Decuypere, Jean-Paul; 55687; Vennekens, Rudi; 18066; Jouret, Francois; Mekahli, Djalila; 62139;
The clinical course of autosomal dominant polycystic kidney disease (ADPKD) starts in childhood. Evidence of the beneficial impact of early nephron-protective strategies and lifestyle modifications on ADPKD prognosis is accumulating. Recent studies have described the association of overweight and obesity with rapid disease progression in adults wit...
Beucher, A Miguel Escalada, I Balboa, D De Vas, M Maestro, MA Garcia-Hurtado, J Bernal, A Gonzalez Franco, R Vargiu, P Heyn, H
...
The biological purpose of long non-coding RNAs (lncRNAs) is poorly understood. Haploinsufficient mutations in HNF1A homeobox A (HNF1A), encoding a homeodomain transcription factor, cause diabetes mellitus. Here, we examine HASTER, the promoter of an lncRNA antisense to HNF1A. Using mouse and human models, we show that HASTER maintains cell-specific...
Whelan, E Kalliala, I Semertzidou, A Raglan, O Bowden, S Kechagias, K Markozannes, G Cividini, S McNeish, I Marchesi, J
...
Several non-genetic factors have been associated with ovarian cancer incidence or mortality. To evaluate the strength and validity of the evidence we conducted an umbrella review of the literature that included systematic reviews/meta-analyses that evaluated the link between non-genetic risk factors and ovarian cancer incidence and mortality. We se...
van Oostrum, N H M de Vet, C M Clur, S B van der Woude, D A A van den Heuvel, E R Oei, S G van Laar, J O E H
Published in
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
Two-dimensional speckle-tracking echocardiography (2D-STE) is a promising technique which allows assessment of fetal cardiac function, and can be used in the evaluation of cardiac and non-cardiac diseases in pregnancy. However, reliable fetal reference values for deformation parameters measured using 2D-STE are needed before it can be introduced in...
Nagrani, Rajini Foraita, Ronja Wolters, Maike De Henauw, Stefaan Marild, Staffan Molnár, Dénes Moreno, Luis A Russo, Paola Tornaritis, Michael Veidebaum, Toomas
...
Published in
Diabetes/metabolism research and reviews
Subclinical systemic inflammation may lead to development of type 2 diabetes, but there has been no investigation into its relationship with early progression of glycaemic deterioration and insulin resistance, especially in younger population. In this study we assessed longitudinal associations of pro- and anti-inflammatory markers with markers tha...
Woelfe, T Linkohr, B Waterboer, T Thorand, B Seissler, J Chadeau, M Peters, A
Introduction: T2D prevalence is increasing worldwide and previous studies suggested that it is higher in individuals seropositive for herpesviruses. This study examines the prospective association of herpesviruses with (pre)diabetes to evaluate their potential role in diabetes aetiology. Methods: Two follow–up examinations of the German population–...
Ong, Yi Ying Pang, Wei Wei Huang, Jonathan Y Aris, Izzuddin M Sadananthan, Suresh Anand Tint, Mya-Thway Yuan, Wen Lun Chen, Ling-Wei Chan, Yiong Huak Karnani, Neerja
...
10.1007/s00394-022-02800-7 / EUROPEAN JOURNAL OF NUTRITION
Ledesma, Jorge R Ma, Jianing Vongpradith, Avina Maddison, Emilie R Novotney, Amanda Biehl, Molly H LeGrand, Kate E Ross, Jennifer M Jahagirdar, Deepa Bryazka, Dana
...
10.1016/S1473-3099(21)00449-7 / LANCET INFECTIOUS DISEASES / 22 / 2 / 222-241
