Firouzi, Mahyar Van Herk, Karlijn Kerckhofs, Eric Swinnen, Eva Baeken, Chris Van Overwalle, Frank Deroost, Natacha
Published in
Journal of neuropsychology
Implicit motor sequence learning (IMSL) is affected in Parkinson's disease (PD). Research in healthy young participants shows the potential for transcranial direct-current stimulation (tDCS) over the primary motor cortex (M1) to enhance IMSL. In PD, only null effects have been reported to date. We determined concurrent, short-term, and long-term ef...
Honinx, Elisabeth Van den Block, Lieve Piers, Ruth Onwuteaka-Philipsen, BD Payne, S Szczerbińska, K Gambassi, G Kylänen, M Deliens, Luc Smets, Tinne
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Background To be able to provide high-quality palliative care, there need to be a number of organizational structures available in the nursing homes. It is unclear to what extent such structures are actually present in nursing homes in Europe. We aim to examine structural indicators for quality of palliative care in nursing homes in Europe and to e...
Hobeika, Lise Ghilain, Matthieu Schiaratura, Loris Lesaffre, Micheline Huvent-Grelle, Dominique Puisieux, François Samson, Séverine
Published in
Scientific Reports
Although music therapy may engender clinical benefits in patients with neurodegenerative disease, the impacts of social and musical factors of such activities on socio-emotional and motor engagements are poorly understood. To address this issue, non-verbal behaviors of 97 patients with or without major cognitive impairment (CI) were assessed when l...
Leonenko, Ganna; Baker, Emily; Stevenson-Hoare, Joshua; Sierksma, Annerieke; 86993; Fiers, Mark; 89478; Williams, Julie; de Strooper, Bart; 12249; Escott-Price, Valentina;
Polygenic Risk Scores (PRS) for AD offer unique possibilities for reliable identification of individuals at high and low risk of AD. However, there is little agreement in the field as to what approach should be used for genetic risk score calculations, how to model the effect of APOE, what the optimal p-value threshold (pT) for SNP selection is and...
Johansson, M Rogmark, C Sutton, R Fedorowski, A Hamrefors, V
Background Impaired orthostatic blood pressure response and syncope confer a high risk of falls and trauma. The relationship between a history of unexplained syncope and orthostatic hypotension (OH) with subsequent fractures, however, has not been thoroughly examined. In this study, we aimed to investigate the relationship between previous hospital...
Monaghan, Thomas F Bliwise, Donald L Choueka, Murray Cunningham, Benjamin S Rahman, Syed N Weiss, Jeffrey P Wein, Alan J
Published in
Annals of physical and rehabilitation medicine
Feleke, R Reynolds, RH Smith, AM Tilley, B Taliun, SAG Hardy, J Matthews, PM Gentleman, S Owen, DR Johnson, MR
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Parkinson's disease (PD), Parkinson's disease with dementia (PDD) and dementia with Lewy bodies (DLB) are three clinically, genetically and neuropathologically overlapping neurodegenerative diseases collectively known as the Lewy body diseases (LBDs). A variety of molecular mechanisms have been implicated in PD pathogenesis, but the mechanisms unde...
Shin, Eun Ji Park, Joon Won
Overlapping of Alzheimer's disease and Parkinson's disease is associated with the formation of hetero-oligomers derived from amyloid-beta and alpha-synuclein. However, the structural identity of the hetero-oligomer has yet to be elucidated, particularly at high resolution. Here, with atomic force microscopy, the surface structure of hetero-oligomer...
Gathercole, Rebecca Bradley, Rosie Harper, Emma Davies, Lucy Pank, Lynn Lam, Natalie Davies, Anna Talbot, Emma Hooper, Emma Winson, Rachel
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Published in
Health technology assessment (Winchester, England)
Many people with dementia living at home are recommended assistive technology and telecare to help them remain living safely and independently in the community. These devices are meant to assist and support activities such as taking medication or cooking, or to raise an alert when there is an issue, such as a fire; however, there is currently littl...
Parks, RM Anderson, GB Nethery, RC Navas-Acien, A Dominici, F Kioumourtzoglou, M-A
Hurricanes and other tropical cyclones have devastating effects on society. Previous case studies have quantified their impact on some health outcomes for particular tropical cyclones, but a comprehensive assessment over longer periods is currently missing. Here, we used data on 70 million Medicare hospitalizations and tropical cyclone exposures ov...
