Honzawa, Tatsuma Matsuo, Kazuhiko Hosokawa, Shunya Kamimura, Mayu Kaibori, Yuichiro Hara, Yuta Nagakubo, Daisuke Oiso, Naoki Kawada, Akira Otsuka, Atsushi
...
Published in
International immunology
T helper 17 (Th17) cells express CC chemokine receptor 4 (CCR4) and secrete cytokines such as interleukin-17A (IL-17A) and granulocyte macrophage colony-stimulating factor (GM-CSF), while dendritic cells (DCs) produce CC chemokine ligand 22 (CCL22), a CCR4 ligand, upon stimulation with GM-CSF. Th17 cells are known to play a critical role in the pat...
Flosdorf, Niclas Zenke, Martin
Published in
European journal of immunology
Novel and exciting avenues allow generating dendritic cells (DC) by reprogramming of somatic cells. DC are obtained from induced pluripotent stem cells (iPS cells), referred to as ipDC, and by direct reprogramming of cells toward DC, referred to as induced DC (iDC). iPS cells represent pluripotent stem cells generated by reprogramming of somatic ce...
Mestrallet, Guillaume Sone, Kazuki Bhardwaj, Nina
Published in
Frontiers in Immunology
Dendritic cells (DCs) play a key role to modulate anti-cancer immunity in the tumor microenvironment (TME). They link innate to adaptive immunity by processing and presenting tumor antigens to T cells thereby initiating an anti-tumor response. However, subsets of DCs also induce immune-tolerance, leading to tumor immune escape. In this regard, the ...
Qian, Yucun Yang, Bo Zeng, Kaidi Zhang, Hao Jiao, Yingying Huang, Xuyong Yu, Hui Qu, Shaojun Zhu, Mengmeng
Published in
Frontiers in Energy Research
Webster, Luke Leaver, Tama Sandry, Eleanor
The COVID-19 pandemic accelerated the importance of streaming within the context of commercial transmedia strategies. While cinemas have remained closed, studios have used streaming to extend audience engagement, and experiment with transmedia strategies attached to large intellectual properties. This paper seeks to determine how the pandemic affec...
radzevičiūtė;, eivina
Gene transfer into primary immune cells as well as into cell lines is essential for scientific and therapeutical applications. One of the methods used for gene transfer is electroporation (EP). EP is a method where a pulsed electric field (PEF) causes a highly transient permeability of the targeted cell membrane. In this work, we present the electr...
Kocheva, SA Gjorgjievska, M Martinova, K Antevska-Trajkova, Z Jovanovska, A Plaseska-Karanfilska, D
Published in
Balkan Journal of Medical Genetics
Dyskeratosis congenita (DC) is a clinically and genetically heterogeneous, multisystem inherited syndrome with a very high risk for bone marrow failure (BMF) and cancer predisposition. The classical clinical form of DC is characterized by abnormal skin pigmentation, nail dystrophy, and oral leukoplakia. Bone marrow failure is considered to be an im...
Weiss, Matjaž Anderluh, Marko Gobec, Martina
The O-GlcNAcylation is a posttranslational modification of proteins regulated by O-GlcNAc transferase (OGT) and O-GlcNAcase. These enzymes regulate the development, proliferation and function of cells, including the immune cells. Herein, we focused on the role of O-GlcNAcylation in human monocyte derived dendritic cells (moDCs). Our study suggests ...
Zhang, Ya-Nan Xing, Xiang-Xin Chen, Liu Dong, Xin Pan, Hao-Tian Hua, Xu-Yun Wang, Ke
Published in
Frontiers in Neurology
Brain functional alteration at different stages of neuropathic pain.
Farzi, Rana Aghbash, Parisa Shiri Eslami, Narges Azadi, Arezou Shamekh, Ali Hemmat, Nima Entezari-Maleki, Taher Baghi, Hossein Bannazadeh
Published in
Pathology, research and practice
Coronavirus Disease 2019 (COVID-19) is one of the three lethal coronavirus outbreaks in the recent two decades and a serious threat to global health all over the world. The principal feature of the COVID-19 infection is the so-called "cytokine storm" exaggerated molecular response to virus distribution, which plays massive tissue and organ injury r...
