Soltan Dallal, M M Validi, M Douraghi, M Bakhshi, B
Published in
New microbes and new infections
Cytotoxin is one of the important pathogenic factors, which plays a role in the virulence of Klebsiella oxytoca. The aim of this study was to investigate molecular typing of clinical isolates of the cytotoxin-producing K. oxytoca using internal transcribed spacer (ITS) PCR. A total of 75 isolates of K. oxytoca were isolated from clinical samples; t...
Lazcano-Pérez, Fernando Zavala-Moreno, Ariana Rufino-González, Yadira Ponce-Macotela, Martha García-Arredondo, Alejandro Cuevas-Cruz, Miguel Gómez-Manzo, Saúl Marcial-Quino, Jaime Arreguín-Lozano, Barbarín Arreguín-Espinosa, Roberto
...
Published in
Journal of Venomous Animals and Toxins including Tropical Diseases
BackgroundCnidarian venoms and extracts have shown a broad variety of biological activities including cytotoxic, antibacterial and antitumoral effects. Most of these studied extracts were obtained from sea anemones or jellyfish. The present study aimed to determine the toxic activity and assess the antitumor and antiparasitic potential of Palythoa ...
Lazcano-Pérez, Fernando Zavala-Moreno, Ariana Rufino-González, Yadira Ponce-Macotela, Martha García-Arredondo, Alejandro Cuevas-Cruz, Miguel Gómez-Manzo, Saúl Marcial-Quino, Jaime Arreguín-Lozano, Barbarín Arreguín-Espinosa, Roberto
...
Abstract Background Cnidarian venoms and extracts have shown a broad variety of biological activities including cytotoxic, antibacterial and antitumoral effects. Most of these studied extracts were obtained from sea anemones or jellyfish. The present study aimed to determine the toxic activity and assess the antitumor and antiparasitic potential of...
Validi, Majid Soltan-Dallal, Mohammad Mehdi Douraghi, Masoumeh Fallah-Mehrabadi, Jalil Rahimi-Foroushani, Abbas Frohesh-Tehrani, Homa
Published in
Microbial pathogenesis
In the current study, the majority of strains isolated from the stool of the patients included cytopathic effects on HEp-2 cells.
Jiménez-Charris, Eliécer Montealegre-Sánchez, Leonel Solano-Redondo, Luis Castro-Herrera, Fernando Fierro-Pérez, Leonardo Lomonte, Bruno
Published in
Toxicon : official journal of the International Society on Toxinology
The Lansberg's hognose pitviper, Porthidium lansbergii lansbergii, inhabits northern Colombia. A recent proteomic characterization of its venom (J. Proteomics [2015] 114, 287-299) revealed the presence of phospholipases A2 (PLA2) accounting for 16.2% of its proteins. The two most abundant PLA2s were biochemically and functionally characterized. Pll...
Wang, Kevin K. W. Yang, Zhihui Chiu, Allen Lin, Fan Rubenstein, Richard
Published in
Molecular Neurobiology
Overexpression of cellular prion protein, PrPC, has cytoprotective effects against neuronal injuries. Inhibition of cell death-associated proteases such as necrosis-linked calpain and apoptosis-linked caspase are also neuroprotective. Here, we systematically studied how PrPC expression levels and cell death protease inhibition affect cytotoxic chal...
Jiménez-Charris, Eliécer Montealegre-Sánchez, Leonel Solano-Redondo, Luis Castro-Herrera, Fernando Fierro-Pérez, Leonardo Lomonte, Bruno
Published in
Toxicon : official journal of the International Society on Toxinology
The Lansberg's hognose pitviper, Porthidium lansbergii lansbergii, inhabits northern Colombia. A recent proteomic characterization of its venom (J. Proteomics [2015] 114, 287-299) revealed the presence of phospholipases A2 (PLA2) accounting for 16.2% of its proteins. The two most abundant PLA2s were biochemically and functionally characterized. Pll...
Alikhani, Mohammad Yousef Shahcheraghi, Fereshteh Khodaparast, Sepideh Mozaffari Nejad, Amir Sasan Moghadam, Mojgan K Mousavi, Sayed Fazlollah
Published in
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology
The cytotoxin-producing K. oxytoca is found to be one of the causes of antibiotic-induced colitis. Discontinuing treatment and allowing normal intestinal flora to be established or prescribing appropriate medication after antibiogram can help patients with antibiotic-induced haemorrhagic colitis in a timely manner.
Wang, Liang Chan, Judy Y W Rêgo, Juciane V Chong, Cheong-Meng Ai, Nana Falcão, Cláudio B Rádis-Baptista, Gandhi Lee, Simon M Y
Published in
Biochimica et biophysica acta
Animal venoms contain a diverse array of proteins and enzymes that are toxic toward various physiological systems. However, there are also some practical medicinal uses for these toxins including use as anti-bacterial and anti-tumor agents. In this study, we identified a nine-residue cryptic oligopeptide, KRFKKFFKK (EVP50) that is repeatedly encode...
Riedel, Thomas Spring, Stefan Fiebig, Anne Scheuner, Carmen Petersen, Jörn Göker, Markus Klenk, Hans-Peter
Published in
Standards in Genomic Sciences
Roseovarius mucosus Biebl et al. 2005 is a bacteriochlorophyll a-producing representative of the marine Roseobacter group within the alphaproteobacterial family Rhodobacteraceae, which was isolated from the dinoflagellate Alexandrium ostenfeldii. The marine Roseobacter group was found to be abundant in the ocean and plays an important role for glob...
