Yazdanian, Mohsen Rostamzadeh, Pouya Alam, Mostafa Abbasi, Kamyar Tahmasebi, Elahe Tebyaniyan, Hamid Ranjbar, Reza Seifalian, Alexander Moghaddam, Mehrdad Moosazadeh Kahnamoei, Majid Balaei
...
Published in
AMB Express
Dental caries and oral infections have become a widespread issue in the modern world. This study aimed to investigate the antibacterial, antifungal, and cytotoxicity characteristics of the extracts of Echinacea purpura , Arctium lappa , and the essential oil of Zataria multiflora as a potential herbal mouthwash. The essential oil of Z. multiflora l...
Mikolajczyk, Agata Khosrawipour, Veria Lau, Hien Li, Shiri Migdal, Pawel Labbé, Maya Karine Kielan, Wojciech Nicpon, Jakub Stieglitz, Sven Khosrawipour, Tanja
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Published in
BMC Pharmacology & Toxicology
Background Recently, taurolidine has been intensively studied on a variety of in-vitro cancer cell-lines and first data exhibit encouraging antitumoral effects. While the clinical use of taurolidine is considered, some studies with in-vivo experiments contradict this beneficial effect and even indicate advanced cancer growth. The aim of this study ...
Clemente, Camila M. Robledo, Sara M. Ravetti, Soledad
Published in
BMC Complementary Medicine and Therapies
Introduction Despite the number of deaths and the significant economic and social costs associated with Chagas, Leishmaniasis and Malaria diseases worldwide, available drugs are limited and have serious side effects and high toxicity for the patient. Therefore, there is an urgent need for safe, low-cost, and effective treatments. Natural products a...
Mukhija, Minky Joshi, Bhuwan Chandra Bairy, Partha Sarathi Bhargava, Anurag Sah, Archana N.
Published in
Beni-Suef University Journal of Basic and Applied Sciences
Background Cancer is considered as the second deadliest disease globally. Plants have continuously offered unique secondary metabolites with remarkable biological applications. Lignans have gained great importance due to their biological activity. Previous studies revealed that the most remarkable bioactivity of lignan class of molecules is antican...
Wong, Chun Y J Ong, Hui Xin Traini, Daniela
Published in
Life sciences
Electronic (e)-cigarettes have been marketed for more than a decade as an alternative to conventional cigarettes. Their popularity and use among adolescents have grown significantly during recent years. While e-cigarettes do not release carcinogenic aromatic hydrocarbons, they can generate reactive carbonyls and radicals during the heating process ...
Pemha, René Le Bot, Damien Mosset, Paul Legrand, Alain Bernard
Published in
Anti-cancer agents in medicinal chemistry
The active ingredients in the shark liver oil (SLO) mixture were found to be a group of etherlinked glycerol known as alkylglycerols (AKGs). During the last century, initial clinical use of the SLO mixture was for treating leukemias and later preventing radiation sickness from cancer x-ray therapy. Selachyl alcohol is one of the most abundant AKGs ...
Kozubek, Marie Hoenke, Sophie Schmidt, Theresa Deigner, Hans-Peter Al-Harrasi, Ahmed Csuk, René
Published in
Steroids
Betulin and betulinic acid derived 30-oxo-amides were prepared by hydroboration, subsequent oxidation and amidation; these novel compounds were screened for their cytotoxic activity by SRB assays. All of the compounds showed significant cytotoxic activity for different human tumor cell lines. Small changes in the structure, however, resulted in sig...
Ranjbar, Sara Khoshneviszadeh, Mehdi Tavakkoli, Marjan Miri, Ramin Edraki, Najmeh Firuzi, Omidreza
Published in
Molecular diversity
Discovery of novel anticancer agents is of crucial importance to expand the therapeutic options for cancer patients. In this study, a series of 49 5-oxo-hexahydroquinoline and 5-oxo-tetrahydrocyclopentapyridine analogs, containing different pyridine alkyl carboxylates at C3 and various aliphatic, aromatic, and heteroaromatic substitutions at the C4...
Mohamed, Aly Fahmy Abuamara, Tamer M M Amer, Mohamed E Ei-Moselhy, Laila E Gomah, Tamer Albasyoni Matar, Emadeldin R Shebl, Rania Ibrahim Desouky, Said E Abu-Elghait, Mohammed
Published in
Journal of gastrointestinal cancer
The present work aimed to study the activity of naturally derived fungal secondary metabolites as anticancer agents concerning their cytotoxicity, apoptotic, genetic, and histopathological profile. It was noticed that Aspergillus terreus, Aspergillus flavus, and Aspergillus fumigatus induced variable toxic potential that was cell type, secondary me...
Paris, Elaine Cristina Malafatti, João Otávio Donizette Moreira, Ailton José Santos, Lílian Cruz Sciena, Camila Rodrigues Zenatti, Alessandra Escote, Márcia Tsuyama Mastelaro, Valmor Roberto Joya, Miryam Rincón
Published in
Environmental science and pollution research international
Photocatalysts supported in magnetic nanocomposites for application in environmental remediation processes have been evaluated for removing contaminants due to easy recovery and low toxicity to the ecosystem. In this work, copper oxide (CuO) nanoparticles with photocatalytic properties were decorated on magnetic support constituted by hydroxyapatit...