Marbun, Prajona Hakim, Arief Rahman Sri Octa Ujiantari, Navista Sulistyo Ari Sudarmanto, Bambang Endro Nugroho, Agung
Published in
BIO Web of Conferences
The absorption-distribution-metabolism-excretion (ADME) profile is a crucial parameter that indicates the pharmacokinetics of the drug. The pharmacokinetic properties of a drug represent the fate of the drug in the body. Curcumin is a main compound in turmeric produced by plants of the Curcuma longa species, and has several pharmacological effects ...
Bose, Susmita Sarkar, Naboneeta Majumdar, Ujjayan
Published in
Colloids and surfaces. B, Biointerfaces
Limitations in the current clinical management of critical-sized osseous defects have driven the need for multifunctional bone constructs. The ideal bone scaffold should possess advanced microarchitecture, well-defined pore interconnectivity, and supply biological signals, which actively guide and control tissue regeneration while simultaneously pr...
Jafari, Hessam Namazi, Hassan
Published in
Colloids and surfaces. B, Biointerfaces
In this study, a pH-responsive hydrogels based on laponite rapid dispersion (Lap®)/chitosan (CS)/polyvinyl alcohol (PVA) designed and was used for controlled delivery of the anticancer drug curcumin (CUR). First, it was accomplished by dissolving CUR in Lap® dispersion under the influence of the pH of the environment. Then, in the presence of Lap®C...
Jiang, Tingting Han, Yu Esmaeilizadeh, Niloufar Barkhordari, Amin Jalil, Abduladheem Turki Saleh, Marwan Mahmood Talaei, Sona Pilehvar, Younes
Published in
Applied biochemistry and biotechnology
Several clinical studies have reported the analgesic effect of curcumin (Curc) in various situations such as rheumatoid arthritis, osteoarthritis, and postsurgical pain. Therefore, in this work, Curc-loaded electrospun nanofibers (NFs) are designed to evaluate their sustained release on analgesic effect duration in rats after epidural placement via...
Erarslan, Ayse Seda Ozmerdivenli, Recep Sirinyıldız, Ferhat Cevik, Ozge Gumus, Erkan Cesur, Gokhan
Published in
Toxicology mechanisms and methods
Ulcerative Colitis (UC) is a disease that negatively affects quality of life and is associated with sustained oxidative stress, inflammation and intestinal permeability. Vitamin D and Curcumin; It has pharmacological properties beneficial to health, including antioxidant and anti-inflammatory properties. Our study investigates the role of Vitamin D...
Pang, Jiadong Zhuang, Baoxiong Zhang, Li-Ming
Published in
International journal of biological macromolecules
Pancreatic cancer is one of the most lethal malignancies in the world and remains one of the leading causes of cancer related death. For its treatment, a lot of investigations have dealt not only with individual chemotherapy by using polymeric carriers to deliver anticancer drugs, but also with individual gene therapy by using polymeric carriers to...
Keyvan, Erhan Kahraman, Hatice Ahu Tutun, Hidayet Dönmez, Soner Şen, Erdi Çalişkan, Zühal Rugji, Jerina Demirtaş, Ahu Akyüz, Ali Özhan
Published in
Food science and technology international = Ciencia y tecnologia de los alimentos internacional
Photodynamic inactivation (PDI) has a potential application for food preservation that can minimize food pathogens posing risks to consumer health. This study aimed to evaluate the antibacterial activity of 405 nm light-emitting diodes (LEDs) illumination in the presence of carvacrol and curcumin against Salmonella Enteritidis and S. Enteritidis PT...
Mosallam, Farag M Bendary, Mahmoud M Elshimy, Rana El-Batal, Ahmed I
Published in
World journal of microbiology & biotechnology
Helicobacter pylori (H. pylori) is the main cause of gastric diseases. However, the traditional antibiotic treatment of H. pylori is limited due to increased antibiotic resistance, low efficacy, and low drug concentration in the stomach. This study developed a Nano-emulsion system with ability to carry Curcumin and Clarithromycin to protect them ag...
Nayak, Deepika Paul, Subarno Das, Chinmay Bhal, Subhasmita Kundu, Chanakya Nath
Published in
Journal of cell communication and signaling
Cancer stem cells (CSCs) cause drug resistance in cancer due to its extensive drug efflux, DNA repair and self-renewal capability. ATP binding cassette subfamily G member 2 (ABCG2) efflux pump afford protection to CSCs in tumors, shielding them from the adverse effects of chemotherapy. Although the role of ABCG2 in cancer progression, invasiveness,...
Basile, Sara Mathew, Essyrose Genta, Ida Conti, Bice Dorati, Rossella Lamprou, Dimitrios A
Published in
Drug delivery and translational research
3D printing has provided a new prospective in the manufacturing of personalized medical implants, including fistulas for haemodialysis (HD). In the current study, an optimized fused modelling deposition (FDM) 3D printing method has been validated, for the first time, to obtain cylindrical shaped fistulas. Printing parameters were evaluated for the ...
