Malmgren, Johan Waldenström, Ann-Charlotte Rylander, Christian Johannesson, Elias Lundin, Stefan
Published in
Critical Care
Background ICU survivorship includes a diverse burden of disease. Current questionnaires used for collecting information about health-related problems and their relation to quality of life lack detailed questions in several areas relevant to ICU survivors. Our aim was to construct a provisional questionnaire on health-related issues based on interv...
Zhou, Tao Zheng, Nan Li, Xiang Zhu, Dongmei Han, Yi
Published in
BMC Emergency Medicine
Background Neutrophil-lymphocyte count ratio (NLCR) has been reported as better indicator of bacteremia than procalcitonin (PCT), and more precise predictor of mortality than C-reactive protein (CRP) under various medical conditions. However, large controversy remains upon this topic. To address the discrepancy, our group has compared the efficienc...
Erstad, Brian L. Barletta, Jeffrey F.
Published in
Critical Care
Medications used for supportive care or prophylaxis constitute a significant portion of drug utilization in the intensive care unit. Evidence-based guidelines are available for many aspects of supportive care but drug doses listed are typically for patients with normal body habitus and not morbid obesity. Failure to account for the pharmacokinetic ...
Michael, M. Kumle, B. Pin, M. Kümpers, P. Gröning, I. Bernhard, M.
Published in
Medizinische Klinik, Intensivmedizin Und Notfallmedizin
Kritisch kranke Patienten werden regelmäßig in der prähospitalen Notfallmedizin versorgt. Gerade an der Nahtstelle zwischen prähospitaler und innerklinischer Versorgung besteht eine große Herausforderung darin, die Patientenbehandlung ohne Zeitverlust und auf hohem Niveau fortzuführen. Hierzu gehören die Stabilisierung der Vitalfunktionen (inkl. At...
Gao, Yue Chen, Lingxi Chi, Jianhua Zeng, Shaoqing Feng, Xikang Li, Huayi Liu, Dan Feng, Xinxia Wang, Siyuan Wang, Ya
...
Published in
Journal of Intensive Care
Background Immune and inflammatory dysfunction was reported to underpin critical COVID-19(coronavirus disease 2019). We aim to develop a machine learning model that enables accurate prediction of critical COVID-19 using immune-inflammatory features at admission. Methods We retrospectively collected 2076 consecutive COVID-19 patients with definite o...
Pellegrini, José Augusto Santos Rech, Tatiana Helena Schwarz, Patrícia de Oliveira, Ana Cláudia Tonelli Vieceli, Tarsila Moraes, Rafael Barberena Sekine, Leo Viana, Marina Verçoza
Published in
Journal of Thrombosis and Thrombolysis
Previous studies have suggested that COVID-19 pneumonia is associated with an increased risk of venous thromboembolism (VTE). This study aimed to investigate the incidence of VTE among mechanically ventilated adults with COVID-19 pneumonia, compared to patients with respiratory failure related to other causes. Prospective study that enrolled critic...
Veldhuis, Lars I. Hollmann, Markus W. Kooij, Fabian O. Ridderikhof, Milan L.
Published in
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background Early pre-hospital identification of critically ill patients reduces morbidity and mortality. To identify critically ill non-traumatic and non-cardiac arrest patients, a pre-hospital risk stratification tool was previously developed in the United States. The aim of this study was to investigate the accuracy of this tool in a Dutch Emerge...
Litton, Edward Anstey, Matt Broadhurst, David Chapman, Andy Currie, Andrew Ferrier, Janet Gummer, Joel Higgins, Alisa Lim, Jolene Manning, Laurens
...
Published in
Intensive Care Medicine
Purpose In adults requiring treatment in an intensive care unit, probiotic therapy using Lactobacillus plantarum 299v may reduce nosocomial infection. The aim of this study was to determine whether early and sustained L. plantarum 299v therapy administered to adult ICU patients increased days alive and at home. Methods A multicentre, parallel group...
Alvarado Sánchez, Jorge Iván Caicedo Ruiz, Juan Daniel Diaztagle Fernández, Juan José Amaya Zuñiga, William Fernando Ospina-Tascón, Gustavo Adolfo Cruz Martínez, Luis Eduardo
Published in
Annals of Intensive Care
IntroductionDynamic predictors of fluid responsiveness have shown good performance in mechanically ventilated patients at tidal volumes (Vt) > 8 mL kg−1. Nevertheless, most critically ill conditions demand lower Vt. We sought to evaluate the operative performance of several predictors of fluid responsiveness at Vt ≤ 8 mL kg−1 by using meta-regressi...
Balihar, Karel Kotyza, Jan Zdrhova, Lucie Kozeluhova, Jana Krcma, Michal Matejovic, Martin
Published in
Critical Care
BackgroundMotility disorders of upper gastrointestinal tract are common in critical illness and associated with significant clinical consequences. However, detailed quantitative and qualitative analyses of esophageal motor functions are lacking. Therefore, we aimed to characterize the key features of esophageal motility functions using high-resolut...
