Algamal, Moustafa Pearson, Andrew J Hahn-Townsend, Coral Burca, Ioana Mullan, Michael Crawford, Fiona Ojo, Joseph O
Published in
Progress in neuro-psychopharmacology & biological psychiatry
The lack of progress in the psychopharmacological treatment of stress-related disorders such as PTSD is an ongoing crisis due to its negative socioeconomic implications. Current PTSD pharmacotherapy relies on a few FDA approved medications used primarily for depression which offer only symptomatic relief and show limited efficacy. As the population...
Fardell, Loren L. Bedoya-Pérez, Miguel A. Dickman, Christopher R. Crowther, Mathew S. Pavey, Chris R. Narayan, Edward J.
Published in
The Science of Nature
Understanding wild animal responses to stressors underpins effective wildlife management. In order for responses to stressors to be correctly interpreted, it is critical that measurements are taken on wild animals using minimally invasive techniques. Studies investigating wild animal responses to stressors often measure either a single physiologica...
Veitch, Jasmine S M Bowman, Jeff Mastromonaco, Gabriela Schulte-Hostedde, Albrecht I
Published in
General and comparative endocrinology
A common response to parasite infestations is increased production of glucocorticoid hormones that regulate immune function. We examined relationships between ectoparasite infestations and fecal corticosterone metabolites (FCM) in deer mice (Peromyscus maniculatus). Furthermore, we experimentally removed fleas to determine if reductions in ectopara...
Cleber Gama de Barcellos Filho, Procópio... Campos Zanelatto, Leonardo Amélia Aparecida Santana, Barbara Calado, Rodrigo T Rodrigues Franci, Celso
Published in
Brain research
Chronic stress is related to the acceleration of telomere shortening. Recent work showed a correlation between chronic psychosocial stress and reduced telomere length in certain cells. The exposure of T lymphocytes to cortisol promoted a significant reduction in telomerase activity. Although stress can promote changes in telomere length, whether in...
Popovska-Perčinić, Florina Manojlović-Stojanoski, Milica Pendovski, Lazo Dinevska Kjovkarovska, Suzana Miova, Biljana Grubin, Jasmina Milošević, Verica Ajdžanović, Vladimir
Published in
Cell journal
As a consequence of global warming, the increase in the average annual temperature is observed, while the living organisms actively adapt to these changes. High environmental temperature initiates numerous physiological, autonomic, and behavioral responses, and activates the stress response. Thus, the aim of the study was to investigate effect of a...
Ruuskanen, Suvi Hsu, Bin-Yan Nord, Andreas
Published in
Molecular and cellular endocrinology
The ability to maintain a (relatively) stable body temperature in a wide range of thermal environments by use of endogenous heat production is a unique feature of endotherms such as birds. Endothermy is acquired and regulated via various endocrine and molecular pathways, and ultimately allows wide aerial, aquatic, and terrestrial distribution in va...
Ahmed, Walaa M S Abdel-Azeem, Naglaa M Ibrahim, Marwa A Helmy, Nermeen A Radi, Abeer M
Published in
Ecotoxicology and environmental safety
The objective of this study was to investigate the influence of deltamethrin (DLM)on brain function and to find whether DLM-induced neurotoxicity is prevented by the treatment with cinnamon oil. Four groups of ten Wistar albino male rats each were used. Group I (control) received saline only. Group II received cinnamon oil alone at 0.5 mg/kg B.W. i...
Krause, Jesse S Pérez, Jonathan H Reid, Angus M A Cheah, Jeffrey Bishop, Valerie Wingfield, John C Meddle, Simone L
Published in
General and comparative endocrinology
Capture-restraint is often used to investigate the acute hypothalamic-pituitary-adrenal axis (HPA) response to stress in wild and captive animals through the production of glucocorticoids. Although this approach is useful for understanding changes in glucocorticoids, it overlooks potential changes in the complex regulatory systems associated with t...
Titon, Stefanny Christie Monteiro Titon Junior, Braz Assis, Vania Regina Vasconcelos-Teixeira, Ronyelle Garcia Neto, Patrício Getúlio Lima, Alan Siqueira Ferreira, Letícia de França Fernandes, Pedro A Gomes, Fernando Ribeiro Markus, Regina P
...
Published in
General and comparative endocrinology
Almost all physiological processes within the organism, including immune parameters and hormones, follow a circadian rhythm. These daily fluctuations are often observed in free-living organisms; however, little is known regarding hormonal and immune daily variations in anurans, particularly under laboratory conditions. This study aimed to investiga...
Himmelstein, Russell Spahija, Ada Fokidis, H Bobby
Published in
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Glucocorticoids (GCs) and dehydroepiandrosterone (DHEA) are steroids secreted by the adrenal glands into circulation to effect distant target tissues and coordinate physiological processes. This classic systemic view of steroids has been challenged by evidence that other tissues can independently synthesize their own steroids. Little is known howev...