Published in BMC Research Notes
ObjectivesA feature of late-life depression is alterations of the stress hormone system. The CYP21A2 gene encodes for the steroid 21-hydroxylase enzyme which is required for the biosynthesis of mineralocorticoids and glucocorticoids, two main components of the stress response in humans. Variants in the CYP21A2 gene could influence risk of late-life...
Published in Egyptian Journal of Neurosurgery
BackgroundSpontaneous intracranial hypotension (SIH) is characterized by positional headache caused by low CSF pressure, without any major traumatic event. Optimal treatment is still debated; epidural blood patch (EBP) is usually used after unsuccessful conservative treatment with variable efficacy and potentially severe complications. Although ste...
Published in BMC Infectious Diseases
BackgroundThis study was performed to investigate clinical features of patients with severe SARS-CoV-2 pneumonia and identify risk factors for converting to severe cases in those who had mild to moderate diseases at the start of the pandemic in China.MethodsIn this retrospective, multicenter cohort study, patients with mild to moderate SARS-CoV-2 p...
Published in Archivos de la Sociedad Espanola de Oftalmologia
The objetive of these study is to know the characteristics of COVID-19 in patients with uveitis associated with Systemic Autoimmune Disease (SAD) through telematic survey. Internal Medicine Society and Group of Systemic Autoimmune disease conducted a telematic survey of patients with SAD to learn about the characteristics of COVID-19 in this popula...
Published in Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
Erworbene Lymphgefäßtumoren sind selten. Das progressive Lymphangiom tritt üblicherweise als kleinere, meist umschriebene Plaque auf und ist durch eine langsame Größenzunahme gekennzeichnet. Bei dem vorgestellten 13-jährigen Jungen zeigte sich hingegen eine sehr ausgedehnte singuläre Veränderung mit klinisch stärkerer Induration ohne extrakutane Be...
Published in World Journal of Clinical Cases
BACKGROUND Central pontine myelinolysis (CPM) usually occurs during rapid correction of serum osmolality, typically with brainstem lesions presenting uniform signals following enhancement on magnetic resonance imaging (MRI). We report a case of CPM caused by diabetes, which was characterized by glioma-like imaging features and the patient responded...
Published in Dubai Medical Journal
Meningitis is an uncommon complication of head trauma. Vasculitis in bacterial meningitis is seen in 9–25% of adults while neurological deficits in bacterial meningitis are seen in about one-third of children. We report a 5-year-old boy, previously healthy who was admitted in March 2019 to Latifa Women’s and Children’s Hospital, Dubai, UAE, with pn...
Published in Pilot and Feasibility Studies
BackgroundPost-traumatic headaches (PTH) are a common sequelae of traumatic brain injury (TBI) and greatly impact patient function and quality of life. Post-traumatic greater occipital neuralgia (GON) is a type of post-traumatic headache. Conventional treatment includes steroid/anesthetic injections which typically alleviate pain but have a short d...
Published in BMC Musculoskeletal Disorders
BackgroundIntra-articular (IA) corticosteroid (CS) injections are the mainstay of treatment for symptomatic management in knee osteoarthritis (OA), particularly in the UK. IA platelet-rich plasma (PRP) injections are a promising alternative, but no systematic reviews to date have compared them to the current standard of care, IA CS injections. We a...
Published in Irish Journal of Medical Science
Myocarditis is a concerning potential consequence of COVID-19 infection, attributed to ventricular dysfunction, cardiac fibrosis, ventricular arrhythmias, cardiogenic shock, and sudden cardiac death. Recently, the Israeli Health Ministry announced that a small number of cases of myocarditis may be linked to second dose of Pfizer’s BioNTech-partnere...
