Goyal, Lajya Devi Garg, Priyanka Kaur, Manmeet
Published in
Journal of Medical Case Reports
Background Lichen planus is a rare autoimmune disease primarily affecting the skin and mucous membranes of the oral mucosa, vulva, and vagina. Diagnosis is difficult and often delayed as the clinicians do not associate the oral symptoms with the genital symptoms. This has a negative impact on the out-of-pocket expenditure and quality of life of the...
Bus, S. R. M. Zambreanu, L. Abbas, A. Rajabally, Y. A. Hadden, R. D. M. de Haan, R. J. de Borgie, C. A. J. M. Lunn, M. P. van Schaik, I. N. Eftimov, F.
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Published in
Trials
Background International guidelines recommend either intravenous immunoglobulin (IVIg) or corticosteroids as first-line treatment for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). IVIg treatment usually leads to rapid improvement and is generally safe, but does not seem to lead to long-term remissions. Corticosteroids act more s...
Jamaati, Hamidreza Hashemian, Seyed MohammadReza Farzanegan, Behrooz Malekmohammad, Majid Tabarsi, Payam Marjani, Majid Moniri, Afshin Abtahian, Zahra Haseli, Sara Mortaz, Esmaeil
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Published in
European Journal of Pharmacology
The aim of this study was to evaluate the clinical effects of dexamethasone administration in patients with mild to moderate acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19). The study included 50 patients who were randomly assigned to the dexamethasone group or control group. Dexamethasone was administered at a...
Naser Moghadasi, Abdorreza Shabany, Maryam Heidari, Hora Eskandarieh, Sharareh
Published in
Clinical Neurology and Neurosurgery
Background Iran is one of the countries with a high prevalence of multiple sclerosis (MS) and COVID-19.MS patients receiving the immunomodulatory or immunosuppressive therapy have a higher risk of infection. Due to the significance of determining the risk factors for getting COVID-19 among MS patients, the present study was designed to assess the r...
Wong, Carlos K.H. Wan, Eric Y.F. Luo, Sihui Ding, Yu Lau, Eric H.Y. Ling, Ping Hu, Xiaowen Lau, Edward C.H. Wong, Jerry Zheng, Xueying
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Published in
EClinicalMedicine
Background The timing of administration of agents and use of combination treatments in COVID-19 remain unclear. We assessed the effectiveness of therapeutics in cohorts in Hong Kong SAR and Anhui, China. Methods We conducted propensity-score analysis of 4771 symptomatic patients from Hong Kong between 21st January and 6th December 2020, and 648 sym...
Macciò, Antonio Oppi, Sara Madeddu, Clelia
Published in
Journal of Ovarian Research
Improving early diagnosis along with timely and effective treatment of COVID-19 are urgently needed. However, at present, the mechanisms underlying disease spread and development, defined prognosis, and immune status of patients with COVID-19 remain to be determined. Patients with severe disease state exhibit a hyperinflammatory response associated...
de Oliveira Filho, Cilomar Martins Vieceli, Tarsila de Fraga Bassotto, Caroline da Rosa Barbato, João Pedro Garcia, Tiago Severo Scheffel, Rafael Selbach
Published in
The Brazilian Journal of Infectious Diseases
Organizing pneumonia emerges as a late phase complication of COVID-19. Corticosteroids are standard therapy for organizing pneumonia, but the question of whether an approach with high dose corticosteroids would be beneficial for patients with organizing pneumonia secondary to COVID-19 remains to be answered. Herein we report a series of three patie...
Bahl, Amit Johnson, Steven Chen, Nai-Wei
Published in
Internal and Emergency Medicine
The optimal timing of initiating corticosteroid treatment in hospitalized patients is unknown. We aimed to assess the relationship between timing of initial corticosteroid treatment and in-hospital mortality in COVID-19 patients. In this observational study through medical record analysis, we quantified the mortality benefit of corticosteroids in t...
Lee, Todd C. McDonald, Emily G. Butler-Laporte, Guillaume Harrison, Luke B. Cheng, Matthew P. Brophy, James M.
Published in
International Journal of Infectious Diseases
Background The global death toll from coronavirus disease 2019 (COVID-19) has exceeded 2 million, and treatments to decrease mortality are needed urgently. Objectives To examine the probabilities of a clinically meaningful reduction in mortality for remdesivir and systemic corticosteroids. Design, setting and participants This was a probabilistic r...
Kanaoka, Kensuke Minami, Seigo Ihara, Shoichi Tanaka, Tsunehiro Yasuoka, Hironao Komuta, Kiyoshi
Published in
Respiratory Medicine Case Reports
Coronavirus disease 2019 (COVID-19) has been reported to induce persistent symptoms even after an acute phase. However, the pathophysiology and treatment of this condition have been unclear. We report two patients who recovered from COVID-19, but presented persistent respiratory symptoms. Their respiratory conditions deteriorated, and computed tomo...
