Controversies in the Indications of Percutaneous Angioplasty Or Coronary Artery Bypass Grafting In The Treatment Of Left...
Published in Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background microRNAs (miRNAs) play important roles in abnormal proliferation and migration of vascular smooth muscle cells (VSMCs), which lead to restenosis in coronary artery disease. Nevertheless, the role of miR-18a-5p and how it works in VSMCs remain unknown. Material/Methods miR-18a-5p expression was determined by fluorescence quantitative rea...
Published in Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background Autologous saphenous vein is the most common choice for coronary artery bypass grafting. This study was conducted to identify and characterize differentially expressed genes (DEGs) induced by overexpressing DEPTOR in human saphenous vein endothelial cells (hsVECs) that might play roles in restenosis. Material/Methods hsVECs isolated from...
Published in Chinese medical journal
冠心病合并2型糖尿病患者经皮冠脉支架术后血小板分布宽度与支架内再狭窄的关系摘要背景:既往研究表明血小板分布宽度(PDW)与冠心病(CAD)患者预后关系密切。但PDW预测支架内再狭窄(ISR)的价值尚未得到充分研究。本研究目的在于探讨PDW与CAD合并2型糖尿病(T2DM)患者经皮冠脉介入支架术(PCI)后支架内再狭窄的关系。 方法:收集2012年1月至2013年12月于中国北京安贞医院住院的冠心病合并2型糖尿病并于我院行经皮冠脉介入支架术的5232名患者。回顾分析入选患者其后3年我院的就诊资料,最终438名再次于我院行经皮冠脉造影的患者纳入本研究。支架内再狭窄定义为造影发现支架内及支架旁5mm内不少于50%管腔丢失。采用SPSS22.0统计软件进行数据处理。符合正态分布的计量资料采用平均值±...
Abstract Background: The place of drug-eluting balloons (DEB) in the treatment of in-stent restenosis (ISR) is not well-defined, particularly in a population of all-comers with acute coronary syndromes (ACS). Objective: Compare the clinical outcomes of DEB with second-generation drug-eluting stents (DES) for the treatment of ISR in a real-world pop...
Published in Chonnam medical journal
Although the angiographic rates of in-stent restenosis (ISR) at later months have reduced dramatically with the introduction of drug-eluting stents (DESs), some patients with ISR after implantation of DES present with acute coronary syndrome (ACS). Here, we sought to identify parameters influencing the likelihood of restenosis with ACS presentation...
Abstract Background: According to common belief, most myocardial infarctions (MIs) are due to the rupture of nonsevere, vulnerable plaques with