Published in Hearing research
In the cochlea, mechano-electrical transduction is preceded by dynamic range compression. Outer hair cells (OHCs) and their voltage dependent length changes, known as electromotility, play a central role in this compression process, but the exact mechanisms are poorly understood. Here we review old and new experimental findings and show that (1) ju...
Published in Environmental science and pollution research international
The leachate drainage volume (LDV) of municipal solid waste (MSW) landfills is crucial to the operation of leachate treatment plant and development at the leachate level, but there is still a lack of reasonable evaluation methods. In this study, the evaluation methods, including both field measurements and numerical simulations, are proposed and ap...
Recent advances in texture analysis and machine learning offer new opportunities to improve the application of imaging to intervertebral disc biomechanics. This study employed texture analysis and machine learning on MRIs to investigate the lumbar disc's response to loading. Thirty-five volunteers (30 (SD 11) yrs.) with and without chronic back pai...
Published in Journal of vascular surgery. Venous and lymphatic disorders
Lymphedema affects >1 in 1000 Americans, most often resulting from breast cancer surgery. Conservative treatment, such as compression garments, combined decongestive therapy (CDT), and pneumatic compression pumps, is the current standard of care. Despite the wide availability of these therapies, lymphedema has remained undertreated worldwide. We in...
Published in Journal of pharmaceutical sciences
Active pharmaceutical ingredients (API) and excipients are often classified as 'brittle' or 'ductile' based on their yield pressure determined through the Heckel analysis. Such a brittle/ductile classification is often correlated to some measure of elasticity, die-wall stresses, and brittle fracture propensities from studies performed with a handfu...
Published in Case Reports in Ophthalmology
A 48-year-old gentleman presented to the ophthalmology department with progressive monocular vision loss, a relative afferent-pupillary defect, decreased color perception, headache, proptosis, and retro-orbital pain. This particular patient’s demographics and disease course did not suggest a “typical” retro-bulbar optic neuritis and highlights the ...
Patients with metastatic breast cancer are at high risk for developing vertebral compression fractures due to underlying bone metastases and bone density loss. Vertebral augmentation techniques including percutaneous vertebroplasty and percutaneous balloon kyphoplasty are techniques used to stabilize compression fractures and improve pain. However,...
Published in European journal of preventive cardiology
This consensus document is proposed to clinicians to provide the whole spectrum of deep vein thrombosis management as an update to the 2017 consensus document. New data guiding clinicians in indicating extended anticoagulation, management of patients with cancer, and prevention and management of post-thrombotic syndrome are presented. More data on ...
Cracks initiated in gears by rolling contact fatigue are subjected to triaxial compression with cyclic shear. In order to determine the crack growth kinetics for such loading, cyclic shear tests with static biaxial compression were performed on bearing steel, and resulted in long cracks propagation in mode II, with many secondary branches which inf...
Published in JSES international
Expandable magnetic rods and intramedullary nails are being used in a number of innovative ways, including limb length discrepancy and scoliosis correction. However, recently, the full complement of these devices has been further explored, with the utilization of their compressive capacity to improve fracture healing. The purpose of the present stu...
