Reeves, J Jeffery Broderick, Ryan C Lee, Arielle M Blitzer, Rachel R Waterman, Ruth S Cheverie, Joslin N Jacobsen, Garth R Sandler, Bryan J Bouvet, Michael Doucet, Jay
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BackgroundEarly experience with indocyanine green-based fluorescent cholangiography during laparoscopic cholecystectomy suggests the potential to improve outcomes. However, the cost-effectiveness of routine use has not been studied. Our objective was to evaluate the cost-effectiveness of fluorescent cholangiography versus standard bright light lapa...
Wynn, Adriane Mussa, Aamirah Ryan, Rebecca Hansman, Emily Simon, Selebaleng Bame, Bame Moreri-Ntshabele, Badani Ramogola-Masire, Doreen Klausner, Jeffrey D Morroni, Chelsea
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BackgroundChlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are extremely common sexually transmitted infections (STIs) that are associated with adverse birth and neonatal outcomes, and the risk of vertical transmission of CT and NG during delivery is high. The majority of CT and NG infections are asymptomatic and missed by the standard of ...
Cui, Christina Liu Luo, William Yu Cosman, Bard Clifford Eisenstein, Samuel Simpson, Daniel Ramamoorthy, Sonia Murphy, James Lopez, Nicole
BackgroundWatch and wait (WW) protocols have gained increasing popularity for patients diagnosed with locally advanced rectal cancer and presumed complete clinical response after neoadjuvant chemoradiation. While studies have demonstrated comparable survival and recurrence rates between WW and radical surgery, the decision to undergo surgery has si...
Line, Breton Bess, Shay Gum, Jeffrey L Hostin, Richard Kebaish, Khaled Ames, Christopher Burton, Douglas Mundis, Gregory Eastlack, Robert Gupta, Munish
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BackgroundPreoperative opioid is associated with poor postoperative outcomes for several surgical specialties, including neurosurgical, orthopedic, and general surgery. Patients with symptomatic adult spinal deformity (SASD) are among the highest patient populations reporting opioid use prior to surgery. Surgery for SASD has been demonstrated to im...
Schwarz, Eleanor Bimla Lewis, Carrie A Dove, Melanie S Murphy, Eryn Zuckerman, Diana Nunez-Eddy, Claudia Tancredi, Daniel J McDonald-Mosley, Raegan Sonalkar, Sarita Hathaway, Mark
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Tubal ligation remains common in the USA, especially among low-income patients. To compare the effectiveness and safety of intrauterine contraceptives (IUC) to laparoscopic tubal ligation for Medicaid clients. We partnered with patient and clinician stakeholders to conduct a retrospective cohort study using California Medicaid claims for patients w...
Bentley, Tanya GK Castillo, Daisy Sadeghi, Nina Piber, Dominique Carroll, Judith Olmstead, Richard Irwin, Michael R
BackgroundAmong the over 5 million informal caregivers for patients with Alzheimer's disease (AD) in the United States (US), over 60% experience insomnia. Research on insomnia treatment efficacy in AD caregivers is limited. An ongoing randomized non-inferiority clinical trial, the Caregiver Sleep Research study, is evaluating whether mindfulness me...
Szilagyi, Peter G Albertin, Christina S Casillas, Alejandra Valderrama, Rebecca Duru, O Kenrik Ong, Michael K Vangala, Sitaram Tseng, Chi-Hong Humiston, Sharon G Evans, Sharon
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BackgroundAdult influenza vaccination rates are low. Tailored patient reminders might raise rates.ObjectiveEvaluate impact of a health system's patient portal reminders: (1) tailored to patient characteristics and (2) incorporating behavioral science strategies, on influenza vaccination rates among adults.DesignPragmatic 6-arm randomized trial acro...
Hays, Ron D Shannon, Zacariah K Long, Cynthia R Spritzer, Karen L Vining, Robert D Coulter, Ian Pohlman, Katherine A Walter, Joan Goertz, Christine M
This study examines Patient-Reported Outcome Measurement Information System (PROMIS®)-29 v1.0 outcomes of chiropractic care in a multi-site, pragmatic clinical trial and compares the PROMIS measures to: 1) worst pain intensity from a numerical pain rating 0-10 scale, 2) 24-item Roland-Morris Disability Questionnaire (RMDQ); and 3) global improvemen...
Maya, Sigal Padda, Guntas Close, Victoria Wilson, Trevor Ahmed, Fareeda Marseille, Elliot Kahn, James G
BackgroundTransmission of SARS-CoV-2 in health care facilities poses a challenge against pandemic control. Health care workers (HCWs) have frequent and high-risk interactions with COVID-19 patients. We undertook a cost-effectiveness analysis to determine optimal testing strategies for screening HCWs to inform strategic decision-making in health car...
O'Brien, Kieran S Sié, Ali Dah, Clarisse Ourohiré, Millogo Ouedraogo, Moussa Boudo, Valentin Arzika, Ahmed Lebas, Elodie Nyatigo, Fanice Godwin, William
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Azithromycin is a promising alternative to amoxicillin in the management of uncomplicated severe acute malnutrition (SAM) as it can be administered as a single dose and has efficacy against several pathogens causing infectious disease and mortality in children under 5. In this pilot trial, we aimed to establish the feasibility of a larger randomize...