腸腫瘍におけるDclk1陽性細胞の遺伝子発現プロファイリング
学位規則第4条第2項該当
腸腫瘍におけるDclk1陽性細胞の遺伝子発現プロファイリング
学位規則第4条第2項該当
Pre-to-post diagnosis weight trajectories in colorectal cancer patients with non-metastatic disease
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Purpose: Previous studies have shown that > 50% of colorectal cancer (CRC) patients treated with adjuvant chemotherapy gain weight after diagnosis. This may affect long-term health. Therefore, prevention of weight gain has been incorporated in oncological guidelines for CRC with a focus on patients that undergo adjuvant chemotherapy treatment. It i...
A mediterranean diet mix has chemopreventive effects in a murine model of colorectal cancer modulating apoptosis and the...
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Objectives: Unhealthy dietary patterns have been associated with colorectal cancer (CRC) onset while Mediterranean Diet (MD) has been proposed for CRC prevention. This study evaluated the effect of a Mediterranean Diet Mix (MD-MIX) on colonic tumors development in A/J mice fed a low-fat (LFD) or a high-fat western diet (HFWD), and injected with the...
GC×GC-(HR)TOFMS in colorectal cancer metabolomics
Colorectal cancer globally affects more than one million new persons each year, and kills more than 700.000. Nevertheless, its diagnosis is still largely based on invasive tissue sampling and gaps remain in the understanding of its pathogenesis, with complex combinations between lifestyle, genetics, epigenetics, chronic inflammation (IBD) and micro...
GC×GC-(HR)TOFMS in colorectal cancer metabolomics
Colorectal cancer globally affects more than one million new persons each year, and kills more than 700.000. Nevertheless, its diagnosis is still largely based on invasive tissue sampling and gaps remain in the understanding of its pathogenesis, with complex combinations between lifestyle, genetics, epigenetics, chronic inflammation (IBD) and micro...
miR-122 Targets X-Linked Inhibitor of Apoptosis Protein to Sensitize Oxaliplatin-Resistant Colorectal Cancer Cells to Ox...
Published in Cellular Physiology and Biochemistry
Background/Aims: Although oxaliplatin is one of the most effective chemotherapeutic drugs used to treat colorectal cancer (CRC), long-term administration usually induces acquired drug resistance during the course of treatment. Thus, there is an urgent need to explore novel strategies to improve the efficiency of cancer therapy. The aim of this stud...
Clinicopathologic Features and Prognostic Factors in Alpha-Fetoprotein-Producing Colorectal Cancer: Analysis of 78 Cases...
Published in Cellular Physiology and Biochemistry
Background/Aims: Alpha-fetoprotein-producing colorectal cancer (AFPP-CRC) is quite rarely seen. This study aimed to elucidate the clinicopathologic characteristics and prognostic factors of AFPP-CRC. Methods: Among 5,051 colorectal cancer patients receiving surgery in the Fudan University Shanghai Cancer Center from 2006 to 2016, we identified 78 p...
Physical activity patterns and the risk of colorectal cancer in the Norwegian Women and Cancer study: a population-based...
Introduction: Colorectal cancer (CRC) remains the second most common cancer in women worldwide. Physical activity (PA) has been associated with reduced risk of CRC; however, this has been demonstrated more consistently in men, while results of studies in women have been largely equivocal. We aimed to further examine the relationship between PA patt...
Physical activity patterns and the risk of colorectal cancer in the Norwegian Women and Cancer study: a population-based...
Introduction: Colorectal cancer (CRC) remains the second most common cancer in women worldwide. Physical activity (PA) has been associated with reduced risk of CRC; however, this has been demonstrated more consistently in men, while results of studies in women have been largely equivocal. We aimed to further examine the relationship between PA patt...
