Asymptomatic and Symptomatic COVID-19 Infections Among Health Care Personnel Before and After Vaccination.
Increasing adiposity and the presence of cardiometabolic morbidity is associated with increased Covid-19-related mortali...
Background: Although obesity, defined by body mass index (BMI), has been associated with a higher risk of hospitalisation and more severe course of illness in Covid-19 positive patients amongst the British population, it is unclear if this translates into increased mortality. Furthermore, given that BMI is an insensitive indicator of adiposity, the...
Influence of center-based child care on development of two-year-olds in a Brazilian cohort
Published in Revista de Saúde Pública
OBJECTIVE To investigate the association between child care attendance since birth and development in two-years-old Brazilian children. METHODS The study used longitudinal data from the 2015 Pelotas Birth Cohort. The childhood development (cognitive, fine and gross motor skills, and language) at two-years-old children was assessed using INTER-NDA (...
Patterns of risk exposure in first 1,000 days of life and health, behavior, and education-related problems at age 4.5: e...
BackgroundChildren who are high priority candidates for early intervention need to be identified to reduce their risk for experiencing problems in development. Those exposed to multiple risk factors are more likely to exhibit problems in development than those exposed to a single or no risk factor. We examined the longitudinal associations between ...
Children’s role in the COVID-19 pandemic: a systematic review of early surveillance data on susceptibility, severity, an...
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Background: SARS-CoV-2 infections have been reported in all age groups including infants, children, and adolescents. However, the role of children in the COVID-19 pandemic is still uncertain. This systematic review of early studies synthesises evidence on the susceptibility of children to SARS-CoV-2 infection, the severity and clinical outcomes in ...
A multicentre validation study of the diagnostic value of plasma neurofilament light.
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Increased cerebrospinal fluid neurofilament light (NfL) is a recognized biomarker for neurodegeneration that can also be assessed in blood. Here, we investigate plasma NfL as a marker of neurodegeneration in 13 neurodegenerative disorders, Down syndrome, depression and cognitively unimpaired controls from two multicenter cohorts: King's College Lon...
Awareness, knowledge and trust in the Greek authorities towards COVID-19 pandemic: results from the Epirus Health Study ...
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Background: To assess the level of knowledge and trust in the policy decisions taken regarding the coronavirus disease (COVID-19) pandemic among Epirus Health Study (EHS) participants. Methods: The EHS is an ongoing and deeply-phenotyped prospective cohort study that has recruited 667 participants in northwest Greece until August 31st, 2020. Level ...
Impact of The daily Mile on children's physical and mental health and educational attainment in primary schools; iMprOVE...
Introduction: School-based active mile initiatives such as The Daily Mile (TDM) are widely promoted to address shortfalls in meeting physical activity recommendations. The iMprOVE Study aims to examine the impact of TDM on children’s physical and mental health and educational attainment throughout primary school. Methods and analysis: iMprOVE is a ...
Use of repurposed and adjuvant drugs in hospital patients with covid-19: multinational network cohort study.
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ObjectiveTo investigate the use of repurposed and adjuvant drugs in patients admitted to hospital with covid-19 across three continents.DesignMultinational network cohort study.SettingHospital electronic health records from the United States, Spain, and China, and nationwide claims data from South Korea.Participants303 264 patients admitted to hosp...
Taxonomic signatures of cause-specific mortality risk in human gut microbiome.
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The collection of fecal material and developments in sequencing technologies have enabled standardised and non-invasive gut microbiome profiling. Microbiome composition from several large cohorts have been cross-sectionally linked to various lifestyle factors and diseases. In spite of these advances, prospective associations between microbiome comp...
