Large-scale deorphanization of Nematostella vectensis neuropeptide G protein-coupled receptors supports the independent ...
status: published
Pattern regulation in a regenerating jellyfish.
Published in eLife
Jellyfish, with their tetraradial symmetry, offer a novel paradigm for addressing patterning mechanisms during regeneration. Here we show that an interplay between mechanical forces, cell migration and proliferation allows jellyfish fragments to regain shape and functionality rapidly, notably by efficient restoration of the central feeding organ (m...
A cell-based boundary model of gastrulation by unipolar ingression in the hydrozoan cnidarian Clytia hemisphaerica.
Published in Developmental biology
In Cnidaria, modes of gastrulation to produce the two body layers vary greatly between species. In the hydrozoan species Clytia hemisphaerica gastrulation involves unipolar ingression of presumptive endoderm cells from an oral domain of the blastula, followed by migration of these cells to fill the blastocoel with concomitant narrowing of the gastr...
Bases cellulaires et moléculaires de la régénération chez la méduse Clytia hemisphaerica
La méduse hydrozoaire Clytia hemisphaerica a une plasticité lui permettant de répondre efficacement à différents types de blessure. Au cours de ma thèse, je me suis intéressée aux processus cellulaires et moléculaires au cours de la régénération de l’organe digestif regroupant la bouche et l’estomac (appelé ‘manubrium’) chez cette méduse. J’ai pu o...
A gonad-expressed opsin mediates light-induced spawning in the jellyfish Clytia.
Published in eLife
Across the animal kingdom, environmental light cues are widely involved in regulating gamete release, but the molecular and cellular bases of the photoresponsive mechanisms are poorly understood. In hydrozoan jellyfish, spawning is triggered by dark-light or light-dark transitions acting on the gonad, and is mediated by oocyte maturation-inducing n...
Adoption of conserved developmental genes in development and origin of the medusa body plan
Published in EvoDevo
BackgroundThe metagenesis of sessile polyps into pelagic medusae in cnidarians represents one of the most ancient complex life cycles in animals. Interestingly, scyphozoans and hydrozoans generate medusae by apparently fundamentally different processes. It is therefore unclear whether medusa formation has evolved independently in different medusozo...
Identification et caractérisation d’ARNs localiséset de protéines maternelschez Clytia hemisphaerica
Chez les métazoaires, les premières phases du développement embryonnaire sont assurées pardes facteurs maternels de nature variée, en attendant le démarrage de l’expression du génomezygotique. Accumulées et positionnées dans l’oeuf au cours de sa formation, ces moléculesconstituent les ressources en nutriments nécessaires et les informations permet...
Origin of primary oocyte polarity and role of Mos kinase in meiotic maturation in the cnidaria model (Clytia hemisphaeri...
L objectif de cette thèse vise à améliorer la compréhension des mécanismes cellulaires et moléculaires impliqués dans l origine de la polarité primaire, animale-végétative (a-v) de l oeuf, ainsi que l étude des molécules et mécanismes de régulation des transitions méiotiques. Pour cela, le modèle d étude choisi a été la méduse, Clytia hemisphaerica...
Acetylcholinesterase activity in Clytia hemisphaerica (Cnidaria)
Cholinesterase activity is known in representatives of all living organisms phyla but the origin of the cholinergic system as known in bilaterian animals is still undeciphered. In particular the implication of cholinesterases in the nervous system of non-bilaterian Metazoa is not well known, We thus chose to investigate this activity in the Clytia ...
Development and evolution of neurosensory cells in Cnidaria (insights from the study of nematogenesis in the Clytia hemi...
Les cnidaires sont un groupe-clé pour étudier l origine et l évolution des cellules nerveuses. Des marqueurs neuronaux de Bilateria sont exprimés dans le bulbe tentaculaire de la méduse de Clytia hemisphaerica, spécialisé dans la production massive de cellules neurosensorielles, les nématocytes. La dynamique de la nématogenèse du bulbe a été étudié...
