Nicoll, Ruairidh Gerasimidis, Konstantinos Forrest, Ewan
Published in
Alcohol and alcoholism (Oxford, Oxfordshire)
Chronic alcohol consumption may result in liver injury and chronic liver disease, but other factors are likely to influence disease progression. Malnutrition, specifically micronutrient deficiency, is frequently associated with both alcohol use disorder and chronic liver disease. We hypothesize that micronutrient deficiencies may affect the progres...
Li, Hui
Published in
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Intercellular crosstalk among various liver cells plays an important role in liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Capillarization of liver sinusoidal endothelial cells (LSECs) precedes fibrosis and accumulating evidence suggests that the crosstalk between LSECs and other liver cells is critical in the development and progr...
Russo, Mark W Casingal, Vincent
Published in
Clinics in liver disease
The number of patients presenting with cirrhosis with kidney injury and the potential need for SLKT is increasing. In 2017, standardized criteria were implemented to identify candidates for SLKT as well as criteria for prioritizing LTA recipients for kidney transplant if they developed kidney failure, which is referred to as the 'safety net rule.' ...
Khatana, Sameed Ahmed M Goldberg, David Seth
Published in
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
There is significant variability in county-level rates of liver disease-related mortality. Although this variability is explained partly by demographics, risk factors for liver disease, and access to specialty liver care, little is known about temporal changes in mortality, and its association with economic prosperity. Therefore, we sought to explo...
Rondon-Berrios, Helbert Velez, Juan Carlos Q
Published in
Clinics in liver disease
Hyponatremia is the most common electrolyte disorder encountered in clinical practice, and it is a common complication of cirrhosis reflecting an increase in nonosmotic secretion of arginine vasopressin as a result of of the circulatory dysfunction that is characteristic of advanced liver disease. Hyponatremia in cirrhosis has been associated with ...
Kovvuru, Karthik Velez, Juan Carlos Q
Published in
Clinics in liver disease
Providing dialysis to patients with liver failure is challenging because of their tenuous hemodynamics and refractory ascites. With better machinery and increased availability, continuous kidney replacement therapy has been successfully delivered to acutely ill patients in liver failure over the past few decades. Intermittent hemodialysis continues...
Wilson, Rachel Williams, Donna M
Published in
The Medical clinics of North America
Cirrhosis is a chronic condition resulting from inflammation and fibrosis of the liver. Patients with cirrhosis may have a myriad of physical examination findings that reflect the severity of the underlying liver disease. Although many signs and symptoms related to cirrhosis are nonspecific, such as abdominal pain, nausea, and malaise, some finding...
Barry, Katherine Finn, Arkadiy
Published in
BMJ case reports
Spontaneous bacterial peritonitis (SBP) is a common complication of liver cirrhosis and abdominal ascites, usually caused by organisms from the Enterobacteriaceae family. A woman in her 40s with a history of alcoholic liver cirrhosis presented to the hospital with dyspnoea, abdominal distention and diffuse abdominal pain. She was found to have seps...
Artru, Florent le Goffic, Charles Pageaux, Georges-Philippe Saliba, Faouzi Louvet, Alexandre
Published in
Journal of hepatology
Noureddin, Nabil Noureddin, Mazen Singh, Amandeep Alkhouri, Naim
Published in
Digestive diseases and sciences
Nonalcoholic fatty liver disease (NAFLD) can progress to advanced fibrosis, especially in patients with type 2 diabetes. Small studies have shown that fibrosis can also regress. We aimed to provide large-scale data on progression and regression of fibrosis in diabetics with NAFLD. Adult diabetic patients with the diagnosis of NAFLD based on ICD-9 c...