Published in Pain medicine (Malden, Mass.)
Individuals with obesity frequently contend with chronic pain, but few studies address the clinical impact of coordinated pain services on this population. The current study addresses this topic by comparing the effectiveness of a comprehensive pain rehabilitation program for patients with and without obesity. A retrospective analysis of registry d...
Published in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine
Irritable bowel syndrome (IBS) is a common, often disabling gastrointestinal (GI) disorder for which there is no satisfactory medical treatment but is responsive to cognitive behavior therapy (CBT). To evaluate the costs and cost-effectiveness of a minimal contact version of CBT (MC-CBT) condition for N = 145 for IBS relative to a standard, clinic-...
Published in Nature Communications
The authors show the endocytotic adaptor subunit called AP2A2 is differentially expressed in CGRP+ nociceptors. Locally inhibiting nociceptor endocytosis with a lipidated AP2 inhibitor peptide reduces acute and chronic pain-like behaviour in mice and rats, indicating prolonged analgesia.
Published in International Journal of Clinical Pharmacy
Background Opioid are currently widely used to manage chronic non-malignant pain (CNMP), but there is a growing concern about harm resulting from opioid misuse and the need for medicine optimization, in which pharmacists could potentially play a key role. Objective This study explored pharmacists' roles, barriers and determinants related to their i...
Published in Pain and Therapy
Background Multidimensional patient-reported outcomes are a critical part of assessing patients to better understand their well-being during treatment. The PROMIS-29 assessment tool is utilized as a component of assessing multidimensional pain scales. It includes patient-reported measures of pain, mood, sleep, social participation, and function. Cu...
Published in Journal of pain and symptom management
Valid instruments for assessing spiritual resources and distress in pain therapy are scarce. The Spiritual Distress and Resources Questionnaire (SDRQ) was developed to fill this gap. The objective of this study was to investigate the SDRQ's psychometric properties. We presented the SDRQ to 219 patients with chronic pain conditions and examined its ...
Published in Schmerz (Berlin, Germany)
Krankenhäuser haben im Rahmen ihres Angebots für eine interdisziplinäre multimodale Schmerztherapie (teilstationär und stationär) immer wieder mit strengen Detailprüfungen der zu kodierenden Prozedurenkodes (OPS 8‑918.xx; 8‑91c) durch Krankenkassen und den Medizinischen Dienst zu kämpfen. Dabei werden regelmäßig die Notwendigkeit der (teil-)station...
Published in Pain Reports
Introduction: Chronic back pain is the leading cause of disability in the United States. Based on the hypothesis that nonspecific back pain may be rooted in a psychophysiologic etiology, we propose a new approach to chronic back pain. Objectives: A pilot study was conducted to assess whether psychophysiologic symptom relief therapy (PSRT) can reduc...
Published in Scientific Reports
This experimental study evaluates the location of thoracic dorsal root ganglions (DRGs) through magnetic resonance imaging (MRI) scans, and evaluates the radiofrequency ablation (RFA) fraction of different puncture approaches on distinct DRG locations. Eight normal adult corpse specimens were used as thoracic spine specimens. An MRI examination was...
Published in Scientific Reports
Maladaptive adult neurogenesis in the mammalian brain has been associated with diverse behaviors including disrupted learning, negative mood disorders and psychiatric conditions. However, its functional role in the generation and maintenance of chronic pathological pain has not yet been elucidated. Using an inducible genetic deletion in vivo mouse ...
