Endo, Yutaka Kitago, Minoru Aiura, Koichi Shinoda, Masahiro Yagi, Hiroshi Abe, Yuta Oshima, Go Hori, Shutaro Nakano, Yutaka Itano, Osamu
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Published in
World Journal of Surgical Oncology
BackgroundWe aimed to evaluate the efficacy and safety of 5-fluorouracil-based neoadjuvant chemoradiotherapy (NACRT) in patients with resectable/borderline resectable pancreatic ductal adenocarcinoma (PDAC).MethodsThis retrospective study investigated the clinicopathological features and > 5-year survival of patients with T3/T4 PDAC who underwent N...
Akagi, Shinsuke Fujiwara, Takashi Nishida, Mai Okuda, Akiko Nagao, Yuka Okuda, Toshikatsu Tokuda, Hidenori Takayanagi, Kazunobu
Published in
Journal of Pharmaceutical Health Care and Sciences
BackgroundOral mucositis is a frequent and severe adverse event in patients undergoing chemoradiotherapy for head and neck cancers, especially grade 3 or 4 mucositis. Occurrence may result in drop-out from treatment, thereby reducing survival. We aimed to clarify the effectiveness and safety of rebamipide mouthwash for oral mucositis in patients wi...
Legouté, Florence Bensadoun, René-Jean Seegers, Valérie Pointreau, Yoann Caron, Delphine Lang, Philippe Prévost, Alain Martin, Laurent Schick, Ulrike Morvant, Benjamin
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Published in
Radiation Oncology
BackgroundLow-level laser therapy (LLLT) also called Photobiomodulation therapy (PBMT) could reduce oral mucositis (OM) incidence and severity in head and neck cancer patients treated by chemoradiotherapy, however randomised data about efficacy and safety are missing with curative dose 4 J/cm2.MethodsThis phase III trial was conducted in patients w...
Park, Sehhoon Joung, Je-Gun Min, Yang Won Nam, Jae-Yong Ryu, Daeun Oh, Dongryul Park, Woong-Yang Lee, Se-Hoon Choi, Yoon La Ahn, Jin Seok
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Published in
Journal for ImmunoTherapy of Cancer
BackgroundThe immunogenomic changes triggered by concurrent chemoradiation therapy (CCRT), a standard neoadjuvant treatment for locally advanced esophageal squamous cell carcinoma (ESCC), are unknown. We aimed to analyze the early immunogenomic changes in ESCC induced by CCRT and to correlate them with clinical outcomes.MethodsWe collected biopsy s...
Marnitz, S. Morgenthaler, J. Kunze, S. Herter, J.
Published in
Der Onkologe
Die primäre kombinierte Radiochemotherapie ist Standard beim lokal fortgeschrittenen und nodal positivem Zervixkarzinom. Eine Kombination aus radikaler Hysterektomie und Radiochemotherapie sollte vermieden werden. Bei histologisch gesicherten Lymphknotenmetastasen paraaortal wird mit EFRT („extended field radiation therapy“) eine exzellente lokale ...
Sakai, Makoto Sohda, Makoto Saito, Hideyuki Kuriyama, Kengo Yoshida, Tomonori Kumakura, Yuji Hara, Keigo Yokobori, Takehiko Miyazaki, Tatsuya Murata, Kazutoshi
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Published in
Cancer Chemotherapy and Pharmacology
BackgroundTo evaluate the efficacy of docetaxel, cisplatin, and 5-fluorouracil as combination chemoradiotherapy (DCF-RT) for cervical esophageal cancer (CEC), we performed a retrospective analysis of CEC patients treated by DCF-RT at a single institution.MethodsWe conducted a single-center retrospective study. Twenty-one patients with CEC who under...
Chen, Lu Huang, Jingjuan Wu, Weihua Ta, Shengjun Xie, Xiaoyi
Published in
The International Journal of Cardiovascular Imaging
Right ventricular (RV) impairment after cancer therapy-related cardiotoxicity and its prognostic implications in lung cancer have not been examined. The present research sought to evaluate RV structure, function, and mechanics in stage III non-small-cell lung cancer (NSCLC) before and after concurrent chemoradiotherapy (CCRT), and to explore the as...
Tominaga, Tetsuro Nagasaki, Toshiya Akiyoshi, Takashi Fukunaga, Yosuke Fujimoto, Yoshiya Yamaguchi, Tomohiro Konishi, Tsuyoshi Nagayama, Satoshi Ueno, Masashi
Published in
Surgery Today
PurposeThe feasibility of neoadjuvant therapy (NAT) for elderly patients with rectal cancer has not been evaluated well.MethodsBetween 2004 and 2014, 506 patients with locally advanced low rectal cancer underwent curative resection. Fifty-four were over 75 years old (elderly group), and 452 were under 75 years old (young group). The patients were d...
Belgioia, Liliana Bacigalupo, Almalina Missale, Francesco Vecchio, Stefania Chiola, Ilaria Callegari, Serena Verzanini, Elisa Peretti, Giorgio Corvò, Renzo
Published in
Medical Oncology
The purpose of this study is to evaluate if, in elderly HNC patients, loco-regional control (LRC) is influenced by average weekly radiation dose (AWD). From 2009 to 2017, 150 consecutive HNC elderly patients were analyzed. AWD was calculated by dividing total dose in Gray by overall treatment time in weeks. Patients were divided in 2 groups: Group ...
Yavas, Guler Yavas, Cagdas
Published in
Journal of Radiation Oncology
IntroductionIn recent years, there has been undoubted progress in the evaluation and development of targeted agents for non-small cell lung cancer (NSCLC). At the same time, remarkable progress in radiation therapy (RT) has been developed largely due to our ability to more effectively focus and deliver radiation to the tumor target volume. Both dev...
