Liu, Wei Yu, Bolong Luo, Yunfan Li, Junzheng Yuan, Xiaofei Wu, Shuting Liang, Bijun Lv, Zehong Li, Yanfei Peng, Xinyu
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Published in
BMC Cancer
BackgroundAlthough the National Comprehensive Cancer Network (NCCN) Guidelines recommend CCRT+AC and IC + CCRT as level 2A evidence for treatment of the locoregionally advanced NPC (II-IVa), IC + CCRT+AC could also be an alternative but it is seldom used because of the low completion rates. This article aimed to compare the effectiveness of the thr...
Zhou, Xi-Lei Yu, Chang-Hua Wang, Wan-Wei Ji, Fu-Zhi Xiong, Yao-Zu Zhu, Wei-Guo Tong, Yu-Suo
Published in
Radiation Oncology
BackgroundThis retrospective study was to assess and compare the toxicity and efficacy of concurrent chemoradiotherapy (CCRT) with S-1 or docetaxel and cisplatin in patients with locally advanced esophageal squamous cell carcinoma (ESCC).MethodsPatients with locally advanced ESCC who received CCRT with S-1 (70 mg/m2 twice daily on days 1–14, every ...
Ho, Ya-Wen Yeh, Kun-Yun Hsueh, Shun-Wen Hung, Chia-Yen Lu, Chang-Hsien Tsang, Ngan-Ming Wang, Hung-Ming Hung, Yu-Shin Chou, Wen-Chi
Published in
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Nutritional counseling is frequently overlooked in cancer patients with normal nutritional status. This study aimed to evaluate the impact of nutritional counseling in head and neck cancer (HNC) patients with normal nutritional status prior to concurrent chemoradiotherapy (CCRT). A total of 243 patients with pretreatment normal nutritional status a...
Niu, Jin-Wei Ning, Wu Liu, Zhi-Ze Pei, Dong-Po Meng, Fan-Qiang Zhou, Lei
Published in
Oncology Research and Treatment
Aim: We aimed to compare the oncological outcomes of laparoscopy and open resection for patients with rectal cancer following neoadjuvant chemoradiotherapy (NCRT). Methods: We searched the publications that compared the efficacy of laparoscopic surgery and open thoracotomy in treatment outcomes of rectal cancer after NCRT. All trials analyzed the s...
Hitt, R Iglesias, L López-Pousa, A Berrocal-Jaime, A Grau, J J García-Girón, C Martínez-Trufero, J Guix, M Lambea-Sorrosal, J Del Barco-Morillo, E
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Published in
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Our previous phase-3 study (TTCC 2503) failed to show overall survival advantage of 2 induction chemotherapy (IC) regimens followed by standard concurrent chemoradiotherapy (CRT) over CRT alone in patients with unresectable locally advanced head and neck squamous-cell carcinoma (LAHNSCC). This study described the long-term survival of those patient...
Lamaj, Enkelejda Vu, Erwin van Timmeren, Janita E. Leonardi, Chiara Marc, Louise Pytko, Izabela Guckenberger, Matthias Balermpas, Panagiotis
Published in
Radiation Oncology
BackgroundDefinitive chemoradiotherapy (CRT) is standard of care for nasopharyngeal carcinoma. Due to the tumor localization and concomitant platinum-based chemotherapy, hearing impairment is a frequent complication, without defined dose-threshold. In this study, we aimed to achieve the maximum possible cochleae sparing.Materials and methodsTreatme...
Sun, Yanwu Wu, Xuejing Lin, Huiming Lu, Xingrong Huang, Ying Chi, Pan
Published in
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
Currently, few studies have focused on the prognostic impact of lymph node regression to neoadjuvant chemoradiotherapy (NCRT) in rectal cancer. This study aimed to explore the prognostic impact of lymph node regression grade (LRG) in patients with locally advanced rectal cancer (LARC) following NCRT and radical surgery and develop a predictive nomo...
Kim, Seo Ree Hong, Ji Hyung Sung, Soo-Yoon Kim, Yeo Hyung Chun, Sang Hoon Lee, Hyun Woo Lee, Jung Soo Ko, Yoon Ho
Published in
BMC Cancer
BackgroundSmall-cell lung cancer (SCLC) is a highly proliferative, rapidly growing tumor with a poor prognosis, even in cases of limited disease (LD). Timely and accurate high-intensity therapy is necessary. For concurrent chemoradiotherapy (CCRT), etoposide/platinum (EP)-based regimens are recommended, although irinotecan/platinum (IP)-based regim...
Janssen, Q. P. van Dam, J. L. Bonsing, B. A. Bos, H. Bosscha, K. P. Coene, P. P. L. O. van Eijck, C. H. J. de Hingh, I. H. J. T. Karsten, T. M. van der Kolk, M. B.
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Published in
BMC Cancer
BackgroundNeoadjuvant therapy has several potential advantages over upfront surgery in patients with localized pancreatic cancer; more patients receive systemic treatment, fewer patients undergo futile surgery, and R0 resection rates are higher, thereby possibly improving overall survival (OS). Two recent randomized trials have suggested benefit of...
Kobayashi, Haruki Wakuda, Kazushige Naito, Tateaki Mamesaya, Nobuaki Omori, Shota Ono, Akira Kenmotsu, Hirotsugu Murakami, Haruyasu Endo, Masahiro Harada, Hideyuki
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Published in
Radiation Oncology
BackgroundPatients with lung cancer and interstitial lung disease treated with radiotherapy are at risk of developing radiation pneumonitis. However, the association between interstitial lung abnormalities (ILAs) and radiation pneumonitis in patients with limited-stage small-cell lung cancer (LS-SCLC) remains unclear. Furthermore, the prognosis is ...
