Ye, Bo Zhang, Yu-Xia Yang, Fei Chen, Hong-Lei Xia, Dong Liu, Ming-Qiu Lai, Bai-Tang
Published in
BMC Cancer
BackgroundThe development of effective chemopreventive agents against cigarette smoke-induced lung cancer could be greatly facilitated by suitable laboratory animal models, such as animals treated with the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). In the current study, we established a novel lung cancer ...
Golijanin, Dragan J. Kakiashvili, David Madeb, Ralph R. Messing, Edward M. Lerner, Seth P.
Published in
World Journal of Urology
Zou, Da-ming Brewer, Molly Garcia, Francisco Feugang, Jean M Wang, Jian Zang, Roungyu Liu, Huaguang Zou, Changping
Published in
Nutrition Journal
BackgroundCancer chemoprevention is a new approach in cancer prevention, in which chemical agents are used to prevent cancer in normal and/or high-risk populations. Although chemoprevention has shown promise in some epithelial cancers, currently available preventive agents are limited and the agents are costly, generally with side effects. Natural ...
Duvoix, Annelyse Blasius, Romain Delhalle, Sylvie Michael Schnekenburger Franck Morceau Henry, Estelle Dicato, Mario Marc Diederich
Published in
Cancer Letters
Chemoprevention is a promising anti-cancer approach with reduced secondary effects in comparison to classical chemotherapy. Curcumin, one of the most studied chemopreventive agents, is a natural compound extracted from Curcuma longa L. that allows suppression, retardation or inversion of carcinogenesis. Curcumin is also described as an anti-tumoral...
Mehta, Rajendra G. Pezzuto, John M.
Published in
Current Oncology Reports
Cancer chemoprevention has traditionally been defined as a dietary or therapeutic approach for the prevention, delay, or reversal of carcinogenesis. We currently expand this definition to include nontoxic applications for patients with established disease. In this context, efficacy can be achieved by selectively altering cell-cycle progression. In ...
McWilliams, Annette Lam, Stephen
Published in
Current Oncology Reports
Lung cancer is the most common cause of cancer death worldwide. The overall 5-year survival rate remains disappointing at 14% or less. Several clinician- and communitybased interventions show promise for reducing lung cancer incidence through prevention and smoking cessation. However, long-term heavy smokers retain a significant lung cancer risk de...
Reddy, Bandaru S. Rao, Chinthalapally V.
Published in
Drugs & Aging
Large bowel cancer is not only the third most frequent cancer in the world but is one of the most common human malignancies in Western countries, including North America. In recent years, multidisciplinary research in epidemiology, molecular biology, and laboratory animal model studies have contributed much to our understanding of the aetiology of ...
Carrillo, J. A. Benítez, J.
Published in
European Journal of Clinical Pharmacology
