Xi, Xueyan Guo, Yang Zhu, Min Wei, Yuhui Li, Gang Du, Boyu Wang, Yunfu
Published in
Virology Journal
BackgroundChemokine levels in severe coronavirus disease 2019 (COVID-19) patients have been shown to be markedly elevated. But the role of chemokines in mild COVID-19 has not yet been established. According to the epidemiological statistics, most of the COVID-19 cases in Shiyan City, China, have been mild. The purpose of this study was to evaluate ...
Turner, Triniti C. Arama, Charles Ongoiba, Aissata Doumbo, Safiatou Doumtabé, Didier Kayentao, Kassoum Skinner, Jeff Li, Shanping Traore, Boubacar Crompton, Peter D.
...
Published in
Malaria Journal
BackgroundPlasmodium falciparum causes the majority of malaria cases worldwide and children in sub-Saharan Africa are the most vulnerable group affected. Non-sterile clinical immunity that protects from symptoms develops slowly and is relatively short-lived. Moreover, current malaria vaccine candidates fail to induce durable high-level protection i...
Bhat, Ajaz A. Nisar, Sabah Maacha, Selma Carneiro-Lobo, Tatiana Correa Akhtar, Sabah Siveen, Kodappully Sivaraman Wani, Nissar A. Rizwan, Arshi Bagga, Puneet Singh, Mayank
...
Published in
Molecular Cancer
Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account for the high mortality rate. The tumor microenvironment (TME) contains several cell types, including fibroblasts, immune cells...
Mazzaferro, Sandro Bagordo, Domenico De Martini, Natalia Pasquali, Marzia Rotondi, Silverio Tartaglione, Lida Stenvinkel, Peter
Published in
Calcified Tissue International
Bone is not only a mineralized and apparently non-vital structure that provides support for locomotion and protection to inner organs. An increasing number of studies are unveiling new biologic functions and connections to other systems, giving the rise to new fields of research, such as osteoimmunology. The bone marrow niche, a new entity in bone ...
Zhang, Benyue Xiao, Gang Mao, Ying Qing Lv, Zhiqiang Huang, Ruo-Pan
Published in
Methods in molecular biology (Clifton, N.J.)
The flow cytometry-based multiplex bead array is an advanced technology using antibody-conjugated multiplex beads to detect soluble targets in a liquid phase. This technology has been widely used for detection of soluble analytes like cytokines, chemokines, allergens, viral antigens, and cancer markers. RayPlex® Multiplex Beads Antibody Array serie...
Kalavi, Khodaberdi Jorjani, Ogholniaz Faghihi, Mohammad Ali Mowla, Seyed Javad
Published in
Cell journal
Leishmaniasis is caused by members of the Leishmania species and constitute a group of infective diseases that range from cutaneous lesions to lethal visceral forms. In infected persons, macrophages recognize and eliminate the parasites via phagocytosis. In order to change a hostile environment into an environment adequate for survival and reproduc...
Giuliani, Cesidio Bucci, Ines Napolitano, Giorgio
Published in
Medical hypotheses
Severe forms of the Coronavirus disease 2019 (COVID-19) are characterized by an enhanced inflammatory syndrome called "cytokine storm" that produces an aberrant release of high amounts of cytokines, chemokines, and other proinflammatory mediators. The pathogenetic role of the "cytokine storm" has been confirmed by the efficacy of immunosuppressive ...
Pardo-de-Santayana, Guillermo Juncal-Ruiz, María Vázquez-Bourgon, Javier Riesco-Dávila, Laura Ortiz-Garcia de la Foz, Victor Pelayo-Terán, José María López-Hoyos, Marcos Crespo-Facorro, Benedicto
Published in
Journal of psychiatric research
Higher levels of pro-inflammatory cytokines are consistently found in the serum of first episode psychosis (FEP) patients and this immune dysfunction could contribute to neural harm. On the other hand, lengthy periods of active psychosis during the early phases of the illness appear to be associated to worst functional outcome. We aim to explore th...
Vantur, Romana Rihar, Marusa Koren, Ana Rijavec, Matija Kopac, Peter Bidovec-Stojkovic, Urska Erzen, Renato Korosec, Peter
Published in
Clinical and Translational Allergy
BackgroundThe role of chemokines in anaphylaxis is unclear.MethodsWe prospectively recruited 49 patients presenting to the emergency department with an acute episode of anaphylaxis and 28 healthy subjects. We measured serum levels of the chemokines CCL2, CCL5, CCL7, CCL8, CCL11, CCL13, CCL17, CCL21, CCL22, CCL24, and CCL26, tryptase, the absolute n...
Palada, Vinko Ahmed, Aisha Siddiqah Freyhult, Eva Hugo, Anders Kultima, Kim Svensson, Camilla I Kosek, Eva
Published in
Journal of neuroimmunology
Neuroinflammation and periphery-to-CNS neuroimmune cross-talk in patients with painful knee osteoarthritis (OA) are poorly understood. We utilized proximity extension assay to measure the level of 91 inflammatory proteins in CSF and serum from OA patients and controls. The patients had elevated levels of 48 proteins in CSF indicating neuroinflammat...
