Hanczuk, Tatjana Weiss, Martin Henes, Leon Engler, Tobias Neis, Felix Henes, Melanie
Published in
Archives of gynecology and obstetrics
This study evaluates the overall treatment indicators and outcomes of patients who underwent loop electrosurgical excision procedure (LEEP) at the Department of Women's Health Tübingen and the impact of certification as a dysplasia unit on treatment quality. Retrospective data analysis of 1596 patients from 2013 to 2018 who underwent LEEP excision ...
Liu, Yujuan Wang, Wenping Zhang, Miao Qu, Dacheng Du, Chengchao Chen, Yan Reng, Jiaojiao Chen, Liming Liu, Shengfeng Yang, Yamei
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Published in
Ultrasound in medicine & biology
The aim of this study was to ascertain the safety of high-intensity focused ultrasound (HIFU) for high-grade cervical intraepithelial neoplasia grade 2/3 (CIN 2/3) in patients with fertility requirements. This was a prospective one-arm study. Consecutive CIN 2/3 patients diagnosed with histopathology were screened, enrolled and treated from Septemb...
Sheng, Binyue Yao, Dongmei Du, Xin Chen, Dejun Zhou, Limin
Published in
European journal of obstetrics, gynecology, and reproductive biology
To establish and validate a risk prediction model for cervical high-grade squamous intraepithelial lesions (HSIL). This retrospective study included patients who underwent cervical biopsies at the Cervical Disease Centre of Maternal and Child Hospital of Hubei Province between January 2021 and December 2021. A total of 1630 patients were divided in...
Liu, Yang Liao, Jing Yi, Xiaojia Pan, Zhengmei Pan, Jing Sun, Chunyi Zhou, Honglin Meng, Yushi
Published in
Archives of gynecology and obstetrics
High-risk human papillomavirus (HR-HPV)-positive but cytology-negative cervical cancer screening results are not uncommon. This study aimed to investigate colposcopy's accuracy and diagnostic value in patients with cytology-negative HR-HPV-positive screening results. This retrospective study included patients with HR-HPV-positive cytology-negative ...
Mirandez, Camila Castelhano Yoneda, Juliana Yoko Gertrudes, Larissa Nascimento Carvalho, Carla Fabrine Derchain, Sophie Teixeira, Julio Cesar Vale, Diama Bhadra
Published in
Archives of gynecology and obstetrics
To describe the results of 610 patients who underwent LEEP and evaluate factors related to a negative margin. A retrospective study of patients treated by LEEP at a colposcopy referral service in Campinas, Brazil, 2017-2019. Patients were referred to treat high-grade squamous intraepithelial lesion or adenocarcinoma in situ suspected by cytology an...
Kasraei, Sara Ghahghaei-Nezamabadi, Akram Seifollahi, Akram Aghajani, Faezeh Nakhostin-Ansari, Amin Zarei, Neda Tehranian, Afsaneh
Published in
Archives of gynecology and obstetrics
Comparison of colposcopy-guided biopsy and endocervical cytologic (ECC) results in patients with negative Papanicolaou (Pap) and positive high-risk (HR) HPV tests in the three groups of HPV 16/18, non-16/18 HR-HPV (other HR-HPV), and concurrent infection of either HPV 16/18 and at least one subtype of other HR-HPVs. This cross-sectional study was c...
Hermansson, Ruth S Olovsson, Matts Gustavsson, Inger Gyllensten, Ulf Lindkvist, Olga Lindberg, Julia Hedlund Lillsunde-Larsson, Gabriella Lindström, Annika K
Published in
Infectious agents and cancer
Cervical cancer prevention for older women can be challenging since there are no specific guidelines for this group. This study aimed to determine the incidence of oncogenic HPV and HPV-related dysplasia in elderly women 5 years after being HPV negative. Invited women participated five years earlier in a study where self-sampling for HPV testing wa...
Okodo, Mitsuaki Okayama, Kaori Tsukakoshi, Natsuko Misawa, Yukimi Tanabe, Kazumasa Teruya, Koji Ito, Chieko Ishii, Yasuyoshi Fujii, Masahiko Oda, Mizue
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Published in
Acta Cytologica
Introduction: The morphology of high-grade squamous intraepithelial lesion (HSIL) on Papanicolaou (Pap) smears widely varied, including syncytial aggregates, sheets, and scattered single cells, and no particular cellular pattern is consistently observed. Therefore, this study aimed to determine whether the menstrual cycle affects the cellular patte...
Andralojc, Karolina M. Elmelik, Duaa Rasing, Menno Pater, Bernard Siebers, Albert G. Bekkers, Ruud Huynen, Martijn A. Bulten, Johan Loopik, Diede Melchers, Willem J. G.
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Published in
BMC Medicine
Background Because most cervical cancers are caused by high-risk human papillomaviruses (hrHPVs), cervical cancer prevention programs increasingly employ hrHPV testing as a primary test. The high sensitivity of HPV tests is accompanied by low specificity, resulting in high rates of overdiagnosis and overtreatment. Targeted circular probe-based RNA ...
Fachetti-Machado, Giselle Figueiredo-Alves, Rosane Ribeiro Moreira, Marise Amaral Rebouças
Published in
Archives of gynecology and obstetrics
To evaluate prevalence and diagnostic performance of three colposcopic images to diagnose squamous and glandular cervical precursor neoplasias. Cross-sectional study, conducted through analysis of stored digital colposcopic images. To evaluate the diagnostic performance of three images, herein named grouped glands, aceto-white villi, and atypical v...