Published in Journal of Neuroinflammation
BackgroundUsutu virus (USUV) is an emerging neurotropic arthropod-borne virus recently involved in massive die offs of wild birds predominantly reported in Europe. Although primarily asymptomatic or presenting mild clinical signs, humans infected by USUV can develop neuroinvasive pathologies (including encephalitis and meningoencephalitis). Similar...
Published in EURASIP Journal on Image and Video Processing
In human anatomy, the central nervous system (CNS) acts as a significant processing hub. CNS is clinically divided into two major parts: the brain and the spinal cord. The spinal cord assists the overall communication network of the human anatomy through the brain. The mobility of body and the structure of the whole skeleton is also balanced with t...
Published in Acute Medicine & Surgery
Neuromyelitis optica is an inflammatory central nervous system disorder characterized by severe optic neuritis and transverse myelitis. We present a case with acute respiratory failure.
Published in Revista do Instituto de Medicina Tropical de São Paulo
Taenia solium is the most common parasitic infection of the central nervous system and it can cause parenchymal or extra-parenchymal lesions. Subarachnoid cysticercosis is a type of extra-parenchymal infection in which the prevalence is not known and racemose NC with cerebellar involvement has been rarely reported. The diagnosis is challenging beca...
Published in Particle and Fibre Toxicology
BackgroundWidespread use of silver in its different forms raises concerns about potential adverse effects after ingestion, the main exposure route for humans. The aim of this study was to investigate in CD-1 (ICR) male mice the tissue distribution and in vivo effects of 4-week oral exposure to 0.25 and 1 mg Ag/kg bw 10 nm citrate coated silver nano...
Published in Cellular and Molecular Neurobiology
Mitochondrial DNA (mtDNA) heteroplasmy is the dynamically determined co-expression of wild type (WT) inherited polymorphisms and collective time-dependent somatic mutations within individual mtDNA genomes. The temporal expression and distribution of cell-specific and tissue-specific mtDNA heteroplasmy in healthy individuals may be functionally asso...
Published in Journal of Neuroinflammation
BackgroundAstrocytes are the predominant glial cell type in the central nervous system (CNS) that can secrete various cytokines and chemokines mediating neuropathology in response to danger signals. D-dopachrome tautomerase (D-DT), a newly described cytokine and a close homolog of macrophage migration inhibitory factor (MIF) protein, has been revea...
Published in Journal of Clinical Neuroscience
Objectives To summarise and discuss current knowledge about SARS-CoV-2-associated infectious/immune-mediated central nervous system (CNS)-disease. Method Literature review. Results Altogether 28 articles were found, which reported 48 patients with SARS-CoV-2-associated infectious/immune-mediated CNS-disease. Age ranged from 22 to 79y. There was mal...
Published in Chinese Neurosurgical Journal
BackgroundTo explore central nervous system (CNS) involvement in this disease, from the perspectives of diagnosis, treatment, and misdiagnosisMethodsTwenty-eight patients with CNS echinococcosis were included in this retrospective study, including 18 males (64.3%) and 10 (35.7%) females. The average age of all the patients were 23.5 years (ranged 4...
Published in BMC Pulmonary Medicine
BackgroundThe purpose of this study was to compare the efficacy of osimertinib (OSI) versus afatinib (AFA) in patients with T790M-positive, non-small-cell lung cancer (NSCLC) and multiple central nervous system (CNS) metastases after failure of initial epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) treatment.MethodsConsecutiv...
