Tang, Yingyue Thiess, Lena Weiler, Sofia M E Tóth, Marcell Rose, Fabian Merker, Sabine Ruppert, Thomas Schirmacher, Peter Breuhahn, Kai
Published in
Cell communication and signaling : CCS
Cell–cell contact in epithelial cells is important for cell polarity, cellular compartmentalisation, as well as tissue architecture during development, homeostasis, and regeneration of adult tissues in metazoans. In this context, adherens junctions (AJs) mechanically sense cell contact information with direct impact on cytoskeletal remodelling, the...
Luyt, Natasha Alethea Beaufort, Sandra Divol, Benoit Setati, Mathabatha Evodia Taillandier, Patricia Bauer, Florian Franz
Published in
World Journal of Microbiology and Biotechnology
Microbial multispecies ecosystems are responsible for many biotechnological processes and are particularly important in food production. In wine fermentations, in addition to the natural microbiota, several commercially relevant yeast species may be co-inoculated to achieve specific outcomes. However, such multispecies fermentations remain largely ...
Cheng, Ji-wen Duan, Li-xia Yu, Yang Wang, Pu Feng, Jia-le Feng, Guan-zheng Liu, Yan
Published in
Cell & Bioscience
BackgroundMesenchymal stem cells (MSCs) play a crucial role in cancer development and tumor resistance to therapy in prostate cancer, but the influence of MSCs on the stemness potential of PCa cells by cell–cell contact remains unclear. In this study, we investigated the effect of direct contact of PCa cells with MSCs on the stemness of PCa and its...
Fan, Xing-Liang Zhang, Yuelin Li, Xin Fu, Qing-Ling
Published in
Cellular and Molecular Life Sciences
Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of various diseases. The therapeutic potential of MSCs is attributed to complex cellular and molecular mechanisms of action including differentiation into multiple cell lineages and regulation of immune responses via immunomodulation. The plasticity of MSCs in immuno...
Coléon, Séverin Assil, Sonia Dreux, Marlène
Published in
Methods in molecular biology (Clifton, N.J.)
Plasmacytoid dendritic cells (pDCs) constitute a unique DC subset specialized in rapid and massive secretion of cytokines, including type I interferon (i.e., IFNα and IFNβ), known to be pivotal for both innate immunity and the onset of adaptive response. The production of type I IFNs by pDCs is primarily induced by the recognition of viral nucleic ...
Tokunaga, Naruwa Kishi, Ryota Sasai, Tomoko Saito, Mikako
Published in
Human Cell
To clarify the potential role of gap junction in cell–cell contact response, the expression of connexin30.3 gene (Cx30.3), a specifically expressed isoform in undifferentiated state of mouse embryonic stem (ES) cell line EB3 was investigated under different cell–cell contact conditions. ES cells were cultured by hanging drop culture method to incre...
Dunker, Susanne Althammer, Julia Pohnert, Georg Wilhelm, Christian
Published in
Microbial Ecology
Massive growth of single species of cyanobacteria is a common phenomenon in many eutrophicated waters worldwide. Allelopathic growth control of phytoplankton species is one suggested mechanism, but still controversially discussed. The fact that the synthesis of biological active compounds requires high energy costs and carbon investment for a singl...
Hayashi, Shuichi Takeichi, Masatoshi
Published in
Journal of cell science
Protocadherins are a group of transmembrane proteins belonging to the cadherin superfamily that are subgrouped into 'clustered' and 'non-clustered' protocadherins. Although cadherin superfamily members are known to regulate various forms of cell-cell interactions, including cell-cell adhesion, the functions of protocadherins have long been elusive....
Luo, Xiaoyu He, Johnny J.
Published in
Journal of NeuroVirology
Astrocytes are the most abundant cells in the central nervous system and play important roles in human immunodeficiency virus (HIV)/neuro-acquired immunodeficiency syndrome. Detection of HIV proviral DNA, RNA, and early gene products but not late structural gene products in astrocytes in vivo and in vitro indicates that astrocytes are susceptible t...
Squires, Paul E. Jones, Peter M. Younis, Mustafa Y.G. Hills, Claire E.
Published in
Vitamins and Hormones