Farhat, Sarah Le, Phuong Kayal, Ehsan Noel, Benjamin Bigeard, Estelle Corre, Erwan Maumus, Florian Florent, Isabelle Alberti, Adriana Aury, Jean-Marc
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Published in
BMC Biology
BackgroundDinoflagellates are aquatic protists particularly widespread in the oceans worldwide. Some are responsible for toxic blooms while others live in symbiotic relationships, either as mutualistic symbionts in corals or as parasites infecting other protists and animals. Dinoflagellates harbor atypically large genomes (~ 3 to 250 Gb), with gene...
Mougkogianni, Maria Kalogeropoulou, Argyro Giakoumakis, Nickolaos Nikiforos Lygerou, Zoi Taraviras, Stavros
Published in
STAR protocols
The recruitment of the minichromosome maintenance complex (MCM) on DNA replication origins is a critical process for faithful genome duplication termed licensing. Aberrant licensing has been associated with cancer and, recently, with neurodevelopmental diseases. Investigating MCM loading in complicated tissues, such as brain, remains challenging. H...
Kwon, Albert Lazar, David Devadas, Srinivas Ford, Bryan
Published in
Proceedings on Privacy Enhancing Technologies
Existing anonymity systems sacrifice anonymity for efficient communication or vice-versa. Onion-routing achieves low latency, high bandwidth, and scalable anonymous communication, but is susceptible to traffic analysis attacks. Designs based on DC-Nets, on the other hand, protect the users against traffic analysis attacks, but sacrifice bandwidth. ...
Tothova, Zuzana Valton, Anne-Laure Venev, Sergey V. Dekker, Job Ebert, Benjamin L.
The cohesin complex plays an essential role in chromosome maintenance and transcriptional regulation. Recurrent somatic mutations in the cohesin complex are frequent genetic drivers in cancer, including myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Here, using genetic dependency screens of stromal antigen 2-mutant (STAG2-mutant)...
Adams, Philipp Fievez, Virginie Schober, Rafaëla Amand, Mathieu Iserentant, Gilles Rutsaert, Sofie Dessilly, Géraldine Vanham, Guido Hedin, Fanny Cosma, Antonio
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Published in
iScience
CD32 has raised conflicting results as a putative marker of the HIV-1 reservoir. We measured CD32 expression in tissues from viremic and virally suppressed humanized mice treated relatively early or late after HIV-1 infection with combined antiretroviral therapy. CD32 was expressed in a small fraction of the memory CD4+ T-cell subsets from differen...
Dang, Anh Thu Strietz, Juliane Zenobi, Alessandro Khameneh, Hanif J Brandl, Simon M Lozza, Laura Conradt, Gregor Kaufmann, Stefan H E Reith, Walter Kwee, Ivo
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Published in
iScience
BTN3A molecules-BTN3A1 in particular-emerged as important mediators of Vγ9Vδ2 T cell activation by phosphoantigens. These metabolites can originate from infections, e.g. with Mycobacterium tuberculosis, or by alterations in cellular metabolism. Despite the growing interest in the BTN3A genes and their high expression in immune cells and various can...
Thys, An Trillet, Kilian Rosińska, Sara Gayraud, Audrey Douanne, Tiphaine Danger, Yannic Renaud, Clotilde C.N. Antigny, Luc Lavigne, Régis Pineau, Charles
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Published in
iScience
Molecular Biology; Immunology; Cell Biology
Nagakubo, Toshiki Tahara, Yuhei O. Miyata, Makoto Nomura, Nobuhiko Toyofuku, Masanori
Published in
iScience
Microbiology; Cell Biology
Hsieh, Ju-Yi Yang, Hao-Ping Tewary, Sunil Kumar Cheng, Hui-Chen Liu, Yi-Liang Tai, Shih-Chieh Chen, Wei-Lin Hsu, Chien-Hui Huang, Ting-Jhen Chou, Chuan-Jung
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Published in
iScience
Biological Sciences; Genetics; Cell Biology; Structural Biology; Cancer
Iudin, Andrii Sarkans, Ugis Koronfel, Mohamed A. Fish, Tom Dobbie, Ian Harkiolaki, Maria Patwardhan, Ardan Kleywegt, Gerard J.
Published in
STAR Protocols
This protocol illustrates the steps necessary to deposit correlated 3D cryo-imaging data from cryo-structured illumination microscopy and cryo-soft X-ray tomography with the BioStudies and EMPIAR deposition databases of the European Bioinformatics Institute. There is currently a real need for a robust method of data deposition to ensure unhindered ...
