Inci, Nurcan Kamali, Dilanur Akyildiz, Erdogan Oguzhan Tahir Turanli, Eda Bozaykut, Perinur
Published in
Frontiers in Aging
Increasing chronological age is the greatest risk factor for human diseases. Cellular senescence (CS), which is characterized by permanent cell-cycle arrest, has recently emerged as a fundamental mechanism in developing aging-related pathologies. During the aging process, senescent cell accumulation results in senescence-associated secretory phenot...
Lenzi, Jacopo Reno, Chiara Skrule, Jolanta Lepiksone, Jana Briģis, Ģirts Dūdele, Alina Pia Fantini, Maria
Published in
International journal of health policy and management
Because quantifying the relative contributions of prevention and medical care to the decline in cardiovascular mortality is controversial, at present mortality indicators use a fifty-fifty allocation to fraction avoidable cardiovascular deaths as being partly preventable and partly amenable. The aim of this study was to develop a dynamic approach t...
Srinivasan, Visish M. Puri, Ajit S. Massari, Francesco Kan, Peter
BACKGROUND: The Woven EndoBridge (WEB) device (Terumno Corp. [parent company of Microvention]) was approved by the U.S. Food and Drug Administration as the first intrasaccular device for intracranial aneurysm treatment in December 2018. Its use has become more common since then, but both trial results and postmarket experiences have raised question...
Yang, Liuqiao Ruan, Lei Zhao, Yanping Lu, Yueqi Shan, Ying Zhang, Yucong Chen, Bangwei Zhang, Cuntai Li, Tao
Published in
Medical science monitor : international medical journal of experimental and clinical research
BACKGROUND Thromboelastography (TEG) is a novel blood viscoelasticity detection method revealing blood coagulation status and has been reported to be helpful in predicting clinical outcomes in patients with cardiovascular diseases (CVD). In this study, we aimed to investigate the association between TEG and CVD. MATERIAL AND METHODS A single-center...
Jardim, Beatriz Cordeiro Migowski, Arn Corrêa, Flávia de Miranda Silva, Gulnar Azevedo e
Published in
Revista de Saúde Pública
OBJECTIVE To analyze the impact of the covid-19 pandemic on mortality from cancer and cardiovascular diseases (CVD) as underlying cause and comorbidity in Brazil and Brazilian regions in 2020. METHODS We used the 2019 and 2020 databases of the Mortality Information System (SIM) to analyze deaths occurring between March and December of each year tha...
Kohls, M Freisling, H Charvat, H Soerjomataram, I Viallon, V Davila-Batista, V Kaaks, R Turzanski-Fortner, R Aleksandrova, K Schulze, MB
...
BACKGROUND: Body mass index (BMI) and cardiometabolic comorbidities such as cardiovascular disease and type 2 diabetes have been studied as negative prognostic factors in cancer survival, but possible dependencies in the mechanisms underlying these associations remain largely unexplored. We analysed these associations in colorectal and breast cance...
Tanaka, Atsushi Toyoda, Shigeru Kato, Toru Yoshida, Hisako Hamasaki, Shuichi Watarai, Masato Ishizu, Tomoko Ueda, Shinichiro Inoue, Teruo Node, Koichi
...
Published in
RMD Open
Objectives Elevated serum urate (SU) levels are associated with arterial atherosclerosis and subsequent cardiovascular events. However, an optimal therapeutic target SU level for delaying atherosclerotic progression in patients with hyperuricaemia remains uncertain. The aim of this analysis was to assess an association between changes in SU level a...
Hufnagel, Antonia Dearden, Laura Twinn, Denise Ozanne, Susan
Obesity and gestational diabetes during pregnancy have multiple short- and long-term consequences for both mother and child. One common feature of pregnancies complicated by maternal obesity and gestational diabetes is maternal hyperinsulinaemia, which has effects on the mother and her adaptation to pregnancy. Even though insulin does not cross the...
Dmytriw, Adam A. Kuhn, Anna L. Puri, Ajit S.
BACKGROUND: To analyse the clinical characteristics of COVID-19 with acute ischaemic stroke (AIS) and identify factors predicting functional outcome. METHODS: Multicentre retrospective cohort study of COVID-19 patients with AIS who presented to 30 stroke centres in the USA and Canada between 14 March and 30 August 2020. The primary endpoint was poo...
Kovell, Lara C. Meyerovitz, Claire V. Skaritanov, Ekaterina Ayturk, M. Didem Person, Sharina D. Kumaraswami, Tara Juraschek, Stephen P. Moore Simas, Tiffany A.
BACKGROUND: Hypertension (HTN) in pregnancy is a leading cause of maternal mortality in the United States. Contraception is widely used, and estrogen-based combined hormonal forms are known to increase blood pressure (BP). With nearly half of pregnancies unplanned and many antihypertensive medications teratogenic, appropriate contraception is criti...