Girerd, Nicolas Cleland, John Anker, Stefan D. Byra, William Lam, Carolyn S. P. Lapolice, David Mehra, Mandeep R. van Veldhuisen, Dirk J. Bresso, Emmanuel Lamiral, Zohra
...
Published in
Scientific Reports
Patients with heart failure (HF) and coronary artery disease (CAD) have a high risk for cardiovascular (CV) events including HF hospitalization, stroke, myocardial infarction (MI) and sudden cardiac death (SCD). The present study evaluated associations of proteomic biomarkers with CV outcome in patients with CAD and HF with reduced ejection fractio...
Honda, Yuki Wakabayashi, Kohei Sato, Chisato Ikeda, Naoko Sato, Ken Suzuki, Toshiaki Shibata, Keita Shinke, Toshiro
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Scientific Reports
Some asymptomatic patients with diabetes mellitus (DM) have critical coronary artery disease (CAD), although the guidelines do not recommend aggressive screening for CAD in asymptomatic patients. Chronic kidney disease (CKD) is among the serious co-morbidities of severe systemic atherosclerosis. Thus, CKD may be associated with potential myocardial...
Lindow, Thomas Ekström, Magnus Brudin, Lars Hedman, Kristofer Ugander, Martin
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Scientific Reports
Premature ventricular contractions (PVCs) during recovery of exercise stress testing are associated with increased cardiovascular mortality, but the cause remains unknown. We aimed to evaluate the association of PVCs during recovery with echocardiographic abnormalities, and their combined prognostic performance. Echocardiographic abnormalities [red...
Simonetto, Cristoforo Rospleszcz, Susanne Kaiser, Jan Christian Furukawa, Kyoji
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Scientific Reports
There is large inter-individual heterogeneity in risk of coronary heart disease (CHD). Risk factors traditionally used in primary risk assessment only partially explain this heterogeneity. Residual, unobserved heterogeneity leads to age-related attenuation of hazard rates and underestimation of hazard ratios. Its magnitude is unknown. Therefore, we...
Tóth, Kata Oroszi, Tamás van der Zee, Eddy A. Nyakas, Csaba Schoemaker, Regien G.
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Scientific Reports
Women with cardiovascular disease may be more susceptible to concomitant mental health problems, such as depression and cognitive decline. Exercise training has beneficial effects on the cardiovascular system as well as on mental functions. Aim of the present study was to study the effects of exercise training on heart, brain and behavior in the is...
Chavoshi, Vajihe Barzin, Maryam Ebadinejad, Amir Dehghan, Pooneh Momeni Moghaddam, Amin Mahdavi, Maryam Hadaegh, Farzad Niroomand, Mahtab Valizadeh, Majid Azizi, Fereidoun
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Published in
Scientific Reports
Ideal cardiovascular health (CVH) is associated with a lower risk of developing cardiovascular diseases. This study aims to investigate the association of CVH metrics with carotid intima-media thickness (cIMT) as a marker of subclinical atherosclerosis in young adults. A cross-sectional study was performed on 1295 adults, average age of 29.7 ± 4.0 ...
Kravchenko, Dmitrij Hart, Christopher Garbe, Stephan Luetkens, Julian A. Isaak, Alexander Mesropyan, Narine Vergnat, Mathieu Leyens, Judith Attenberger, Ulrike Kuetting, Daniel
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Scientific Reports
To explore the image quality and radiation dose of dual source high-pitch cardiac computed tomography with tailored contrast injection protocols for pediatric congenital heart disease patients (CHD). In total, 27 infants with CHD (median age 109 days [IQR 6–199]) were retrospectively analyzed regarding dose length product (DLP) and effective dose (...
Kristensen, Charlotte Burup Myhr, Katrine Aagaard Grund, Frederik Fasth Vejlstrup, Niels Hassager, Christian Mattu, Raj Mogelvang, Rasmus
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Scientific Reports
Increased left ventricular mass (LVM) is a strong independent predictor for adverse cardiovascular events, but conventional echocardiographic methods are limited by poor reproducibility and accuracy. We developed a novel method based on adding the mean wall thickness from the parasternal short axis view, to the left ventricular end-diastolic volume...
Khanam, Riffat Sengupta, Arunima Mukhopadhyay, Dipankar Chakraborty, Santanu
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Scientific Reports
Pathological cardiac remodeling as an aftermath of a severe cardiac injury can lead to ventricular dysfunction and subsequent heart failure. Adamts4, a metalloproteinase, and disintegrin with thrombospondin-like motif, involved in the turnover of certain extracellular matrix molecules and pathogenesis of osteoarthritis, also plays a role in cardiac...
Thom, Robyn P. Palumbo, Michelle L. Keary, Christopher J. Hooker, Jacob M. McDougle, Christopher J. Ravichandran, Caitlin T.
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Scientific Reports
Adults with autism spectrum disorder (ASD) are at risk for excess bodyweight and hypertension, yet the prevalence of and clinical predictors for these health conditions remain unknown. The objective of this study was to assess the prevalence of overweight, obesity, and hypertension in a large clinical sample of adults with a confirmed diagnosis of ...