Publication search
with Cardiac function as keyword

Hesperidin ameliorates signs of the metabolic syndrome and cardiac dysfunction via IRS/Akt/GLUT4 signaling pathway in a ...

Published in European journal of nutrition

Hesperidin has been reported to have biological activities such as antihypertensive, hypoglycemic, and antioxidant effects. This study investigated whether hesperidin could improve signs of the metabolic syndrome and cardiac function in a high-fat diet (HFD) induced metabolic syndrome (MS) in rats. Male Sprague-Dawley rats were fed HFD and 15% fruc...

Sectm1a deficiency aggravates inflammation-triggered cardiac dysfunction through disruption of LXRα signalling in macrop...

Published in Cardiovascular research

Cardiac dysfunction is a prevalent comorbidity of disrupted inflammatory homeostasis observed in conditions such as sepsis (acute) or obesity (chronic). Secreted and transmembrane protein 1a (Sectm1a) has previously been implicated to regulate inflammatory responses, yet its role in inflammation-associated cardiac dysfunction is virtually unknown. ...

CD133+Exosome Treatment Improves Cardiac Function after Stroke in Type 2 Diabetic Mice.

Published in Translational stroke research

Cardiac complications post-stroke are common, and diabetes exacerbates post-stroke cardiac injury. In this study, we tested whether treatment with exosomes harvested from human umbilical cord blood derived CD133+ cells (CD133+Exo) improves cardiac function in type 2 diabetes mellitus (T2DM) stroke mice. Adult (3-4 m), male, BKS.Cg-m+/+Leprdb/J (db/...

Optogenetic Control of Cardiac Autonomic Neurons in Transgenic Mice.

Published in Methods in molecular biology (Clifton, N.J.)

Optogenetic technology has enabled unparalleled insights into cellular and organ physiology by providing exquisite temporal and spatial control of biological pathways. Here, an optogenetic approach is presented for selective activation of the intrinsic cardiac nervous system in excised perfused mouse hearts. The breeding of transgenic mice that hav...

Entraînement en musculation et remodelage myocardique : Influence du sexe, du niveau de pratique et de la prise régulièr...

Ces dernières années, la pratique de la musculation s’est largement démocratisée et regroupe aujourd’hui différents types de pratiquants, allant de la personne sédentaire en reprise d’activité au sportif de haut niveau pratiquant le culturisme. L’objectif de ces travaux de thèse a été d’étudier l’impact cardiaque de l’entraînement en musculation ch...

Adjuvant Treatment with 5-Fluorouracil and Oxaliplatin Does Not Influence Cardiac Function, Neurovascular Control, and P...

Published in The oncologist

Adjuvant chemotherapy with 5-fluorouracil (5-FU) and oxaliplatin increases recurrence-free and overall survival in patients with colon adenocarcinoma. It is known that these drugs have been associated with cardio- and neurotoxicity. We investigated the effects of 5-FU ± oxaliplatin on cardiac function, vascular responses, neurovascular control, and...

Impaired cardiac function is associated with mortality in patients with acute COVID-19 infection.

Published in Clinical research in cardiology : official journal of the German Cardiac Society

COVID-19 infection may cause severe respiratory distress and is associated with increased morbidity and mortality. Impaired cardiac function and/or pre-existing cardiovascular disease may be associated with poor prognosis. In the present study, we report a comprehensive cardiovascular characterization in the first consecutive collective of patients...

Study protocol for prospect trial to elucidate the utility of echocardiography-based cardiac output in acute heart failu...

Published in Journal of echocardiography

Early worsening heart failure (WHF), defined as worsening of symptoms and signs of heart failure requiring intensification of medical or mechanical therapy during an admission for acute decompensated heart failure (ADHF), has recently been recognized as a risk of morbidity or mortality after the discharge. Although echocardiographic parameters of l...