Velanis, Christos N Perera, Pumi Thomson, Bennett de Leau, Erica Liang, Shih Chieh Hartwig, Ben Förderer, Alexander Thornton, Harry Arede, Pedro Chen, Jiawen
...
Published in
PLoS genetics
A large fraction of plant genomes is composed of transposable elements (TE), which provide a potential source of novel genes through "domestication"-the process whereby the proteins encoded by TE diverge in sequence, lose their ability to catalyse transposition and instead acquire novel functions for their hosts. In Arabidopsis, ANTAGONIST OF LIKE ...
Galluzzi, Lorenzo Vitale, Ilio Warren, Sarah Adjemian, Sandy Agostinis, Patrizia Martinez, Aitziber Buqué Chan, Timothy A Coukos, George Demaria, Sandra Deutsch, Eric
...
Published in
Journal for Immunotherapy of Cancer
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune response associated with immunological memory, provided they display sufficient antigenicity and adjuvanticity. Moreover, multiple intracellular and microenvironmental features determine the propensity of RCD to drive adaptive immunity. Here, we provide an upd...
Lukasik, Zuzanna Elewaut, Dirk Venken, Koen
Published in
Cancers
Recent progress in immunobiology has led to the observation that, among cells classically categorized as the typical representatives of the adaptive immune system, i.e., T cells, some possess the phenotype of innate cells. Invariant T cells are characterized by T cell receptors recognizing a limited range of non-peptide antigens, presented only in ...
Galpin, Kristianne J.C. Cook, David P. Salemi, Louisa M. Urowitz, Sara Williams, Christine Bell, John C. Brundage, Michael D. Vanderhyden, Barbara C.
The fifth Canadian Cancer Research Conference (CCRC) took place 3-5 November 2019 in Ottawa, Ontario. With nearly 1000 participants, scientists, oncologists, community members, and patients gathered together to share knowledge, foster collaborations, and fuel the future of cancer research in Canada. The scientific program included three plenary ses...
Naert, Thomas Dimitrakopoulou, Dionysia Tulkens, Dieter Demuynck, Suzan Carron, Marjolein Noelanders, Rivka Eeckhout, Liza Van Isterdael, Gert Deforce, Dieter Vanhove, Christian
...
Alterations of the retinoblastoma and/or the p53 signaling network are associated with specific cancers such as high-grade astrocytoma/glioblastoma, small-cell lung cancer (SCLC), choroid plexus tumors, and small-cell pancreatic neuroendocrine carcinoma (SC-PaNEC). However, the intricate functional redundancy between RB1 and the related pocket prot...
Novikova, Polina Brennan, Ian G. Booker, William Mahony, Michael Doughty, Paul Lemmon, Alan R. Moriarty Lemmon, Emily Roberts, J. Dale Yant, Levi Van de Peer, Yves
...
Polyploidy has played an important role in evolution across the tree of life but it is still unclear how polyploid lineages may persist after their initial formation. While both common and well-studied in plants, polyploidy is rare in animals and generally less understood. The Australian burrowing frog genus Neobatrachus is comprised of six diploid...
Holmes, Keith Pötschger, Ulrike Pearson, Andrew D. J. Sarnacki, Sabine Cecchetto, Giovanni Gomez-Chacon, Javier Squire, Roly Freud, Enrique Bysiek, Adam Matthyssens, Lucas E.
...
PURPOSE
To evaluate the impact of surgeon-assessed extent of primary tumor resection on local progression and survival in patients in the International Society of Pediatric Oncology Europe Neuroblastoma Group High-Risk Neuroblastoma 1 trial.
PATIENTS AND METHODS
Patients recruited between 2002 and 2015 with stage 4 disease > 1 year or stage 4/4S wi...
Garcia, E. G. Veloso, A. Oliveira, M. L. Allen, J. R. Loontiens, S. Brunson, D. Do, D. Yan, C. Morris, R. Iyer, S.
...
Baguet, Tristan Verhoeven, Jeroen Pauwelyn, Glenn Hu, Jiyun Lambe, Patricia De Lombaerde, Stef Piron, Sarah Donche, Sam Descamps, Benedicte Goethals, Ingeborg
...
Loontiens, Siebe Vanhauwaert, Suzanne Depestel, Lisa Dewyn, Givani Van Loocke, Wouter Moore, Finola E. Garcia, Elaine G. Batchelor, Lance Borga, Chiara Squiban, Barbara
...
