Dumond, Aurore Brachet, Etienne Durivault, Jérôme Vial, Valérie Puszko, Anna K. Lepelletier, Yves Montemagno, Christopher Pagnuzzi-Boncompagni, Marina Hermine, Olivier Garbay, Christiane
...
Published in
Journal of Experimental & Clinical Cancer Research
BackgroundDespite the improvement of relapse-free survival mediated by anti-angiogenic drugs like sunitinib (Sutent®), or by combinations of anti-angiogenic drugs with immunotherapy, metastatic clear cell Renal Cell Carcinoma (mccRCC) remain incurable. Hence, new relevant treatments are urgently needed. The VEGFs coreceptors, Neuropilins 1, 2 (NRP1...
Parker, Roses S McKeever, Stephen Twycross, Alison Wiseman, Theresa
Published in
Journal of child health care : for professionals working with children in the hospital and community
Children with cancer experience pain throughout their cancer trajectory. Pain has short- and long-term negative consequences for children physically and psychologically. Children with cancer spend more time at home with their families and less time in hospital. While this has benefits for quality of life, it shifts responsibility for pain managemen...
Stefler, Denes Brett, Daniel Sarkadi-Nagy, Eszter Kopczynska, Ewa Detchev, Stefan Bati, Aniko Scrob, Mircea Koenker, Diane Aleksov, Bojan Douarin, Elodie
...
Published in
European journal of nutrition
Cardiovascular disease (CVD) and cancer mortality rates in Eastern Europe are among the highest in the world. Although diet is an important risk factor, traditional eating habits in this region have not yet been explored. This analysis assessed the relationship between traditional dietary pattern and mortality from all-causes, CVD and cancer in Eas...
Zaghloul, Hala Abbas, Ahmed Abdulah, Dina
Published in
Journal of gastrointestinal cancer
To explore the implication of CD8+- and FOXP3+-labeled T lymphocytes invading tumor microenvironment in prognosticating curatively treated rectal cancer with preoperative chemo-radiation. The diagnostic rectal biopsies from clinical T3-T4 and any nodal diseases or any T stage with nodal involvement were processed to quantify (CD8+and FOXP3+). The i...
Pérez-Martinez, Antonio Guerra-García, Pilar Melgosa, Marta Frauca, Esteban Fernandez-Camblor, Carlota Remesal, Agustin Calvo, Cristina
Published in
European journal of pediatrics
Limited information is available regarding SARS-CoV-2 infections in children with underlying diseases. A retrospective study of children less than 15 years old with primary or secondary immunosuppression infected with SARS-CoV-2 during March 2020 was performed. In this series, 8 immunocompromised patients with COVID-19 disease are reported, account...
Moore, John Merchant, Zoe Rowlinson, Kirsty McEwan, Karen Evison, Matthew Faulkner, Gemma Sultan, Javed McPhee, Jamie S Steele, James
Published in
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Patients undergoing major cancer interventions such as major surgical resection, chemotherapy, radiotherapy, and immunotherapy are prone to the adverse effects of their cancer, as well as to the side effects of the treatments designed to cure them. The Prehabilitation process supports cancer patients in preparing for the physiological challenges of...
Jessen, Erik Liu, Yuanhang Davila, Jaime Kocher, Jean-Pierre Wang, Chen
Published in
BMC medical genomics
Traditionally, mutational burden and mutational signatures have been assessed by tumor-normal pair DNA sequencing. The requirement of having both normal and tumor samples is not always feasible from a clinical perspective, and led us to investigate the efficacy of using RNA sequencing of only the tumor sample to determine the mutational burden and ...
Teh, H. S. Woon, Y. L.
Published in
BMC Public Health
Background This is a systematic assessment of the burden of cancers in Malaysia in 2018 using epidemiologic approach. The purpose of this study was to identify the proportion of cancers in Malaysia that were attributable to the modifiable risk factors of excess weight, alcohol intake, physical inactivity, tobacco smoking and to estimate the number ...
Couitchéré, Line Coze, Carole Atiméré, Yao Nicaise Ouattara, Joseph N'doumy, Max Akoun, Charles Yao, Guy Constant Cissé, Lacina
Published in
Bulletin du cancer
To promote the early diagnosis of pediatric cancers in Ivory Coast, we have initiated a program to train local physicians in the warning signs and to raise public awareness. The aim of this work was to compare the times, stages and survival of patients before and three years after the initiation of the program. This retrospective study involved chi...
Herget, Georg Saravi, Babak Schwarzkopf, Eugenia Wigand, Mara Südkamp, Norbert Schmal, Hagen Uhl, Markus Lang, Gernot
Published in
World Journal of Surgical Oncology
Background Skeletal-related events (SREs) due to bone metastases (BM) significantly impact the morbidity and mortality of cancer patients. The present study sought to investigate clinicopathological characteristics, metastasis-free survival (MFS), and SREs in patients referred to a tertiary orthopedic and trauma center. Methods Data were retrieved ...