It is long hypothesized that there is a reliable, specific mapping between certain emotional states and the facial movements that express those states. This hypothesis is often tested by asking untrained participants to pose the facial movements they believe they use to express emotions during generic scenarios. Here, we test this hypothesis using,...
The appearance of genetic changes in human pluripotent stem cells (hPSCs) presents a concern for their use in research and regenerative medicine. Variant hPSCs that harbor recurrent culture-acquired aneuploidies display growth advantages over wild-type diploid cells, but the mechanisms that yield a drift from predominantly wild-type to variant cell...
Fructo-oligosaccharides (FOS) are prebiotics with numerous health benefits. So far, the dissolved oxygen (DO) concentration control strategy for fermentative production of FOS is still unknown. In order to improve FOS production, the effects of DO concentration and fermentation mode on FOS using Aureobasidium pullulans were investigated in this stu...
Fructo-oligosaccharides (FOS) are prebiotics with numerous health benefits. So far, the dissolved oxygen (DO) concentration control strategy for fermentative production of FOS is still unknown. In order to improve FOS production, the effects of DO concentration and fermentation mode on FOS using Aureobasidium pullulans were investigated in this stu...
Cílem diplomové práce bylo navrhnout konverzi budov u předmostí Železničního mostu, na Smíchově v Praze. Návrh vychází z urbanistické studie vypracované v předdiplomní práci. Jedná se o zastavěnou oblast v severní a jižní části Železničního mostu na Smíchovské straně náplavky. Současně se projekt zaobírá řešením propojení těchto dvou celků do jedno...
Cette étude est essentiellement une synthèse des 29 travaux de recherche disponibles sur la communauté utopique d'Awra Amba en Éthiopie, complétée par l'analyse de données issues de la communauté elle-même. Cela permet de présenter les racines puis l'évolution historique tourmentée de cette communauté créée en 1972 par un petit groupe de paysans an...
Народы как фундамент нации стали ассоциировать себя не с общим глобальным государственным устройством, а с этнической принадлежностью, происходит процесс глобализации. Интерпретация событий давно прошедшего времени в контексте сомнения и намеренного отвлеченного мышления приводит к новому сознанию своего исторического контекста. Герой как образ при...
Traditional Chinese medicine therapy, which can serve as adjuvant therapy for cancer treatment, has no obvious side effects on the human body. Geniposide (GEN), one of the main iridoid glycosides in gardenia fruit, has been widely reported to have anti-cancer effects. In this study, we aimed to inspect whether GEN could inhibit proliferation and pr...
Traditional Chinese medicine therapy, which can serve as adjuvant therapy for cancer treatment, has no obvious side effects on the human body. Geniposide (GEN), one of the main iridoid glycosides in gardenia fruit, has been widely reported to have anti-cancer effects. In this study, we aimed to inspect whether GEN could inhibit proliferation and pr...
Human embryonic stem cells (hESCs) and embryonal tumors share a number of common features, including a compromised G1/S checkpoint. Consequently, these rapidly dividing hESCs and cancer cells undergo elevated levels of replicative stress, inducing genomic instability that drives chromosomal imbalances. In this context, it is of interest that long-t...
