Ogland-Hand, Jonathan D. Adams, Benjamin M. Bennett, Jeffrey A. Middleton, Richard S.
Published in
Frontiers in Energy Research
CO2 Plume Geothermal (CPG) power plants can use gigatonne-levels of CO2 sequestration to generate electricity, but it is unknown if the resources that support low-cost CPG power align with the resources that support low-cost CO2 sequestration. Here, we estimate and compare the geospatially-distributed cost of CPG and CO2 storage across a portion of...
Krupa, Petr Siddiqui, Ahad M Grahn, Peter J Islam, Riazul Chen, Bingkun K Madigan, Nicolas N Windebank, Anthony J Lavrov, Igor A
Published in
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
Evidence from preclinical and clinical research suggest that neuromodulation technologies can facilitate the sublesional spinal networks, isolated from supraspinal commands after spinal cord injury (SCI), by reestablishing the levels of excitability and enabling descending motor signals via residual connections. Herein, we evaluate available eviden...
Yu, Bin Wang, Ya Gao, Shangbang
Published in
Frontiers in Molecular Neuroscience
Motor rhythm is initiated and sustained by oscillatory neuronal activity. We recently discovered that the A-class excitatory motor neurons (MNs) (A-MNs) function as intrinsic oscillators. They drive backward locomotion by generating rhythmic postsynaptic currents (rPSCs) in body wall muscles. Molecular underpinning of the rPSCs, however, is not ful...
Thiry, Louise Lemaire, Chloé Rastqar, Ali Lemieux, Maxime Peng, Jimmy Ferent, Julien Roussel, Marie Beaumont, Eric Fawcett, James P. Brownstone, Robert M.
...
Published in
eNeuro
Axon guidance receptors such as deleted in colorectal cancer (DCC) contribute to the normal formation of neural circuits, and their mutations can be associated with neural defects. In humans, heterozygous mutations in DCC have been linked to congenital mirror movements, which are involuntary movements on one side of the body that mirror voluntary m...
Chalif, Joshua I Martínez-Silva, María de Lourdes Pagiazitis, John G Murray, Andrew J Mentis, George Z
Published in
Cell
Locomotion is a complex behavior required for animal survival. Vertebrate locomotion depends on spinal interneurons termed the central pattern generator (CPG), which generates activity responsible for the alternation of flexor and extensor muscles and the left and right side of the body. It is unknown whether multiple or a single neuronal type is r...
Shachykov, Andrii Frère, Julien Henaff, Patrick
This paper presents a neuro-musculoskeletal simulation approach to human gait based on an original model of central pattern generator and the muscle synergy approach. The controller, shown here, aims at simplifying movement control by reducing the number of parameters to optimize. The model of the simplified motor coordination chain was built, from...
Pi, Tingting Lang, Guangping Liu, Bo Shi, Jingshan
Published in
Current neuropharmacology
High methionine-diet (HMD) causes Alzheimer's disease (AD)-like symptoms. Previous studies have shown that Dendrobium nobile Lindle. alkaloids (DNLA) have potential benefits for AD Object: The objective of this study has been to explore whether DNLA can improve AD-like symptoms induced by HMD. Mice were fed with 2% HMD diet for 11 weeks; the DNLA20...
Xie, Linling Jiang, Xiaotao Chen, Yi Huang, Cihui Chen, Yanfen Liu, Guantong Sun, Wenxi Zeng, Lei Lu, Ruling
Published in
Combinatorial chemistry & high throughput screening
Polycystic ovary syndrome (PCOS) is a common endocrine disease in women that seriously interferes with patient's metabolic and reproductive functions. The current diagnostic criteria for PCOS are expert-based and still disputed. Previous studies have identified changes in DNA methylation in peripheral blood of women with PCOS, but their diagnostic ...
Ranjan, Ankit
Rhythmic motion in organisms is driven by central pattern generators (CPG). A CPG converts high-level input from the brain to low-level oscillatory input to the muscles via neuron spikes. Here a particular CPG, a reciprocal inhibition oscillator(RIO), is connected to an underdamped pendulum with position feedback to form a closed-loop system. Two t...
Hari, Pankaj Alhasan, Khalid Bagga, Arvind Bonilla-Felix, Melvin Coccia, Paula Alejandra Duzova, Ali Ha, Ill-So Montini, Giovanni Nakanishi, Koichi Samuel, Susan
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Published in
Pediatric nephrology (Berlin, Germany)
Clinical practice guidelines (CPGs) are systematically developed statements backed by scientific evidence to assist practitioners in management in clinical practice. An international cross-sectional survey was conducted by the IPNA to examine the perceptions of pediatric nephrologists on guidelines and their usage and to identify important diseases...
