Guan, Xin Zhang, Bo Fu, Ming Li, Mengying Yuan, Xu Zhu, Yaowu Peng, Jing Guo, Huan Lu, Yanjun
Published in
Annals of medicine
To appraise effective predictors for COVID-19 mortality in a retrospective cohort study. A total of 1270 COVID-19 patients, including 984 admitted in Sino French New City Branch (training and internal validation sets randomly split at 7:3 ratio) and 286 admitted in Optical Valley Branch (external validation set) of Wuhan Tongji hospital, were inclu...
Loomba, Rohit S Aggarwal, Gaurav Aggarwal, Saurabh Flores, Saul Villarreal, Enrique G Farias, Juan S Lavie, Carl J
Published in
Annals of medicine
To utilize publicly reported, state-level data to identify factors associated with the frequency of cases, tests, and mortality in the USA. Retrospective study using publicly reported data collected included the number of COVID-19 cases, tests and mortality from March 14th through April 30th. Publicly available state-level data was collected which ...
Dioh, W. Chabane, M. Tourette, C. Azbekyan, A. Morelot-Panzini, C. Hajjar, L. A. Lins, M. Nair, G. B. Whitehouse, T. Mariani, J.
...
Published in
Trials
ObjectivesAs of December, 1st, 2020, coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2, resulted in more than 1 472 917 deaths worldwide and death toll is still increasing exponentially. Many COVID-19 infected people are asymptomatic or experience moderate symptoms and recover without medical intervention. However, older people and those wit...
Aflaki, Mona Flannery, Alexandria Ferreira, João Pedro Cheng, Matthew Pellan Kronfli, Nadine Marelli, Ariane Zannad, Faiez Brophy, James Afillalo, Jon Huynh, Thao
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Published in
Trials
ObjectivesThe aim of the RAAS-COVID-19 randomized control trial is to evaluate whether an upfront strategy of temporary discontinuation of renin angiotensin aldosterone system (RAAS) inhibition versus continuation of RAAS inhibition among patients admitted with established COVID-19 infection has an impact on short term clinical and biomarker outcom...
Bailey, Rahn K Saldana, Adrienne M Saldana, Andrea M
Published in
Journal of racial and ethnic health disparities
This is a literature review where we acknowledge Richard Allen Williams, the first African American physician to win the John P. McGovern Compleat Physician Award, and recognize his achievements in race and ethnicity in healthcare. There have been significant advances in the diagnosis and treatment of cardiovascular disease; however, racial dispari...
Fritz, Matthieu Rosolen, Béatrice Krafft, Emilie Becquart, Pierre Elguero, Eric Vratskikh, Oxana Denolly, Solène Boson, Bertrand Vanhomwegen, Jessica Gouilh, Meriadeg Ar
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Published in
One health (Amsterdam, Netherlands)
In a survey of household cats and dogs of laboratory-confirmed COVID-19 patients, we found a high seroprevalence of SARS-CoV-2 antibodies, ranging from 21% to 53%, depending on the positivity criteria chosen. Seropositivity was significantly greater among pets from COVID-19+ households compared to those with owners of unknown status. Our results hi...
Bosveld, Matthijs H van Doorn, Daan P C Stassen, Patricia M Westerman, Dewa Bergmans, Dennis C J J van der Horst, Iwan C C van Mook, Walther N K A
Published in
Journal of critical care
An overview of the experiences with deployment of undergraduate medical students in a Dutch university center during the COVID-19 pandemic is provided from organisational and educational perspectives. Medical students' and specialists' experiences during the first peak of COVID-19 underscore the preliminary suggestion that students can be given mor...
Bardaweel, Sanaa K. Hajjo, Rima Sabbah, Dima A.
Published in
Acta Pharmaceutica
Recently, an outbreak of a fatal coronavirus, SARS-CoV-2, has emerged from China and is rapidly spreading worldwide. Possible interaction of SARS-CoV-2 with DPP4 peptidase may partly contribute to the viral pathogenesis. An integrative bioinformatics approach starting with mining the biomedical literature for high confidence DPP4-protein/gene assoc...
Simões E Silva, Ana Cristina Lanza, Katharina Palmeira, Vitória Andrade Costa, Larissa Braga Flynn, Joseph T
Published in
Pediatric nephrology (Berlin, Germany)
The last decade was crucial for our understanding of the renin-angiotensin-aldosterone system (RAAS) as a two-axis, counter-regulatory system, divided into the classical axis, formed by angiotensin-converting enzyme (ACE), angiotensin II (Ang II), and the angiotensin type 1 receptor (AT1R), and the alternative axis comprising angiotensin-converting...
Botti, Cecilia Lusetti, Francesca Neri, Tommaso Peroni, Stefano Castellucci, Andrea Salsi, Pierpaolo Ghidini, Angelo
Published in
Auris, nasus, larynx
Patients with acute respiratory failure due to COVID-19 have a high likelihood of needing prolonged intubation and may subsequently require tracheotomy. Usually, the choice of technique (percutaneous dilatational tracheotomy [PDT] versus open surgical tracheotomy [OST]) depends on the preference of surgeons and patient-related factors. In case of C...
