Guan, Xin Zhang, Bo Fu, Ming Li, Mengying Yuan, Xu Zhu, Yaowu Peng, Jing Guo, Huan Lu, Yanjun
Published in
Annals of medicine
To appraise effective predictors for COVID-19 mortality in a retrospective cohort study. A total of 1270 COVID-19 patients, including 984 admitted in Sino French New City Branch (training and internal validation sets randomly split at 7:3 ratio) and 286 admitted in Optical Valley Branch (external validation set) of Wuhan Tongji hospital, were inclu...
Dioh, W. Chabane, M. Tourette, C. Azbekyan, A. Morelot-Panzini, C. Hajjar, L. A. Lins, M. Nair, G. B. Whitehouse, T. Mariani, J.
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Published in
Trials
ObjectivesAs of December, 1st, 2020, coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2, resulted in more than 1 472 917 deaths worldwide and death toll is still increasing exponentially. Many COVID-19 infected people are asymptomatic or experience moderate symptoms and recover without medical intervention. However, older people and those wit...
Aflaki, Mona Flannery, Alexandria Ferreira, João Pedro Cheng, Matthew Pellan Kronfli, Nadine Marelli, Ariane Zannad, Faiez Brophy, James Afillalo, Jon Huynh, Thao
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Published in
Trials
ObjectivesThe aim of the RAAS-COVID-19 randomized control trial is to evaluate whether an upfront strategy of temporary discontinuation of renin angiotensin aldosterone system (RAAS) inhibition versus continuation of RAAS inhibition among patients admitted with established COVID-19 infection has an impact on short term clinical and biomarker outcom...
Fritz, Matthieu Rosolen, Béatrice Krafft, Emilie Becquart, Pierre Elguero, Eric Vratskikh, Oxana Denolly, Solène Boson, Bertrand Vanhomwegen, Jessica Gouilh, Meriadeg Ar
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Published in
One health (Amsterdam, Netherlands)
In a survey of household cats and dogs of laboratory-confirmed COVID-19 patients, we found a high seroprevalence of SARS-CoV-2 antibodies, ranging from 21% to 53%, depending on the positivity criteria chosen. Seropositivity was significantly greater among pets from COVID-19+ households compared to those with owners of unknown status. Our results hi...
Bardaweel, Sanaa K. Hajjo, Rima Sabbah, Dima A.
Published in
Acta Pharmaceutica
Recently, an outbreak of a fatal coronavirus, SARS-CoV-2, has emerged from China and is rapidly spreading worldwide. Possible interaction of SARS-CoV-2 with DPP4 peptidase may partly contribute to the viral pathogenesis. An integrative bioinformatics approach starting with mining the biomedical literature for high confidence DPP4-protein/gene assoc...
Verma, Vaijinath A Saundane, Anand R Meti, Rajkumar S Vennapu, Dushyanth R
Published in
Journal of molecular structure
A series of hybrid indolo[3,2-c]isoquinoline (δ-carboline) analogs incorporating two pyrimidine and piperizine ring frameworks were synthesized. Intending biological activities and SAR we propose replacements of fluorine, methyl and methoxy of synthetic compounds for noteworthy antimicrobial, antioxidant, anticancer and anti-tuberculosis activities...
Karmaker, Chitra Lekha Ahmed, Tazim Ahmed, Sayem Ali, Syed Mithun Moktadir, Md Abdul Kabir, Golam
Published in
Sustainable production and consumption
Motivated by the COVID-19 pandemic and the challenges it poses to supply chain sustainability (SCS), this research aims to investigate the drivers of sustainable supply chain (SSC) to tackle supply chain disruptions in such a pandemic in the context of a particular emerging economy: Bangladesh. To achieve this aim, a methodology is proposed based o...
Gu, Tianshu Yao, Lan Meng, Xia Graff, J Carolyn Thomason, Donald Li, Jing Dong, Wei Jiao, Yan Aleya, Lotfi Maida, Marcello
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Published in
The Science of the total environment
The most effective measure to prevent or stop the spread of infectious diseases is the early identification and isolation of infected individuals through comprehensive screening. At present, in the COVID-19 pandemic, such screening is often limited to isolated regions as determined by local governments. Screening of potentially infectious individua...
Parashar, Neha Hait, Subrata
Published in
The Science of the total environment
The COVID-19 pandemic has reemphasized the indispensable role of plastics in our daily life. Plastics in terms of personal protective equipment (PPEs) and other single-use medical equipment along with packaging solutions owing to their inherent properties have emerged as a life-savior for protecting the health and safety of the frontline health wor...
Subpiramaniyam, Sivakumar
Published in
The Science of the total environment
Due to the wide range of viability on inanimate surfaces and fomite transmission of SARS-CoV-2, hydrogen peroxide (0.5%, HP) and hypochlorite-based (0.1%, HC) disinfectants (common biocides) are proposed by World Health Organization to mitigate the spread of this virus in healthcare settings. They can be adopted and applied to outdoor environments....
