Full-spectrum (FUSE) versus standard forward-viewing colonoscopy in an organised colorectal cancer screening programme.
...Published in Gut
ISRCTN10357435.
Comparing CT colonography and flexible sigmoidoscopy: a randomised trial within a population-based screening programme.
...Published in Gut
NCT01739608; Pre-results.
British Society of Gastroenterology position statement on serrated polyps in the colon and rectum
...
Serrated polyps have been recognised in the last decade as important premalignant lesions accounting for between 15% and 30% of colorectal cancers. There is therefore a clinical need for guidance on how to manage these lesions; however, the evidence base is limited. A working group was commission by the British Society of Gastroenterology (BSG) End...
Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma.
Published in Gut
SSAs containing dysplasia/carcinoma are predominantly small (
Comparing CT colonography and flexible sigmoidoscopy: A randomised trial within a population-based screening programme
...
BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumorigenesis
...
OBJECTIVE: Blood vessel epicardial substance (BVES) is a tight junction-associated protein that regulates epithelial-mesenchymal states and is underexpressed in epithelial malignancy. However, the functional impact of BVES loss on tumorigenesis is unknown. Here we define the in vivo role of BVES in colitis-associated cancer (CAC), its cellular func...
Molecular markers for colorectal cancer screening.
Published in Gut
Colorectal cancer (CRC), although a significant cause of morbidity and mortality worldwide, has seen a declining incidence and mortality in countries with programmatic screening. Faecal occult blood testing and endoscopic approaches are the predominant screening methods currently. The discovery of the adenoma-carcinoma sequence and a greater unders...
Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer.
...Published in Gut
Characterisation of colorectal cancer (CRC) genomes by next-generation sequencing has led to the discovery of novel recurrently mutated genes. Nevertheless, genomic data has not yet been used for CRC prognostication. To identify recurrent somatic mutations with prognostic significance in patients with CRC. Exome sequencing was performed to identify...
NEOPLASTIC CHANGE IN A DUPLICATED COLON.
Published in The British journal of surgery
EFFECT OF MALIGNANT GROWTH ON THE ORGAN LACTIC DEHYDROGENASE IN THE HUMAN.
Published in Cancer
