Published in Gut
Raf kinase inhibitor protein (RKIP) appears to control cancer cell metastasis and its expression in colonic tissue is related to colonic cancer development. We sought to identify the roles of RKIP in maintaining homeostasis of GI tract. The expression of RKIP was determined by immunohistochemistry and western blot analysis. RKIP knockout and wild-t...
Published in Gut
Neurotensin (NT) mediates colonic inflammation through its receptor neurotensin receptor 1 (NTR1). NT stimulates miR-133α expression in colonic epithelial cells. We investigated the role of miR-133α in NT-associated colonic inflammation in vitro and in vivo.miR-133α and aftiphilin (AFTPH) levels were measured by quantitative PCR. Antisense (as)-miR...
Published in Gut
Neurotensin (NT) mediates colonic inflammation through its receptor neurotensin receptor 1 (NTR1). NT stimulates miR-133α expression in colonic epithelial cells. We investigated the role of miR-133α in NT-associated colonic inflammation in vitro and in vivo. miR-133α and aftiphilin (AFTPH) levels were measured by quantitative PCR. Antisense (as)-mi...
Published in Gut
Published in BMJ open gastroenterology
Clostridium difficile is a major cause of nosocomial infectious diarrhoea. Treatment of C. difficile infection (CDI) depends on disease severity. A combination of vancomycin and metronidazole is often recommended in severe cases. The aim of this study was to examine, in a murine model of CDI, if mice treated with a combination of vancomycin and met...
Published in British medical journal
Published in The American journal of roentgenology, radium therapy, and nuclear medicine
Published in The British journal of surgery
Published in Annals of internal medicine
