Selviler-Sizer, Sedef Kabak, Yonca Betil Kabak, Murat
Published in
Microscopy research and technique
Telocytes, new interstitial cells that have received significant attention in recent years, have been detected in many organs, including the heart. The distinction between telocytes and other interstitial cells can only be made based on their ultrastructural characterization and immunophenotypic features. In this study, we examined the interstitial...
Shmuly, Tom Ben Zvi, Yehonatan Chaushu, Gabriel Kaplan, Ilana
Published in
Medicina
Background and Objectives: This was a retrospective single-center study to analyze and describe the clinical and histological features of all cases of oral solitary fibrous tumor (SFT). Study design: the study included all consecutive cases of oral SFT diagnosed between 2008–2018 at a single tertiary center. Materials and Methods: Clinical data was...
Shimizu, Yuji Maeda, Takahiro
Published in
Environmental Health and Preventive Medicine
Recent studies have revealed an inverse association between height and cardiovascular disease. However, the background mechanism of this association has not yet been clarified. Height has also been reported to be positively associated with cancer. Therefore, well-known cardiovascular risk factors, such as increased oxidative stress and chronic infl...
Yang, Hui Liu, Lan Li, Gai Chen, Yinchen Jiang, Dong Wang, Wei Wang, Tianyuan Sun, Jinshan Che, Jianfang Gu, Dongmei
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Published in
Therapeutics and Clinical Risk Management
Aim To explore the growth-promoting effect of vacuum sealing drainage (VSD) during the healing processes of diabetic foot ulcers (DFUs). Methods From November 2018 to December 2019, 38 patients with unilateral DFUs were enrolled in this retrospective study. All patients were divided into two groups according to the use of VSD or not: the VSD group ...
Sharma, Mugdha Bhavani, Chandra Suresh, Srinag Bangalore Paul, John Yadav, Lokendra Ross, Cecil Srivastava, Sweta
Published in
Oncology Letters
Myeloproliferative neoplasms (MPN) are clonal disorders characterized by the increased proliferation of hematopoietic stem cell precursors and mature blood cells. Mutations of Janus kinase 2 ( JAK 2), Calreticulin ( CALR ) and MPL (myeloproliferative leukemia virus) are key driver mutations in MPN. However, the molecular profile of triple negative ...
Shapiro, Jenny Tovin, Adi Iancu, Ortal Allen, Daniel Hendel, Ayal
Published in
Methods in molecular biology (Clifton, N.J.)
Human CD34+ hematopoietic stem and progenitor cells (HSPCs) have the unique ability to repopulate the entire hematopoietic system and thus are at the center of diverse, therapeutically relevant studies. The recent development of the CRISPR/Cas9 tool made the powerful research technique of genome editing highly accessible. Our previous studies demon...
Verdelli, Chiara Forno, Irene Morotti, Annamaria Maggiore, Riccardo Mari, Gilberto Vicentini, Leonardo Ferrero, Stefano Kuhn, Elisabetta Vaira, Valentina Corbetta, Sabrina
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Published in
Endocrine-related cancer
Tumors of the parathyroid glands are highly vascularized and display a microRNA (miRNA) profile divergent from normal parathyroid glands (PaNs). Angiogenic miRNAs, namely miR-126-3p, miR-126-5p, and miR-296-5p, have been found downregulated in parathyroid tumors. Here, we show that miR-126-3p expression levels are reduced in parathyroid adenomas (P...
Maqsood, Afsheen Ali, Anwar Zaffar, Zareena Mokeem, Sameer Mokeem, Sara S. Ahmed, Naseer Al-Hamoudi, Nawwaf Vohra, Fahim Javed, Fawad Abduljabbar, Tariq
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Published in
International Journal of Environmental Research and Public Health
To reduce morbidity and mortality rates of OSCC cases, early diagnosis, assessment of behavior and prognostic estimates are vital. This study analyzed the expression of CD34 and alpha smooth muscle actin (α-SMA) in OSCC, to establish their significance in diagnosis and prognosis. Primary cases of OSCC, diagnosed with excisional biopsy at multiple c...
Sopo, Minna Anttila, Maarit Muukkonen, Oona-Tuuli YlÄ-Herttuala, Seppo Kosma, Veli-Matti Keski-Nisula, Leea Sallinen, Hanna
Published in
Anticancer research
Examine features of blood and lymphatic vessels in ovarian tumors and their significance to prognosis of ovarian cancer. A total of 139 women with epithelial ovarian tumors were included: 86 malignant, 17 borderline and 36 benign. Density, percentage, mean size and number of blood microvessels in tumors were measured by immunohistochemistry with an...
Kusmartseva, Irina Wu, Wenting Syed, Farooq Van Der Heide, Verena Jorgensen, Marda Joseph, Paul Tang, Xiaohan Candelario-Jalil, Eduardo Yang, Changjun Nick, Harry
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Published in
Cell Metabolism
Kusmartseva et al. demonstrate preferential ACE2 expression in pancreatic microvascular and ductal structures, suggesting these constitute a more likely target than islet endocrine cells in SARS-CoV-2 infection. This notion was supported by detection of SARS-CoV-2 nucleocapsid protein in ductal epithelium, but not endocrine cells, of pancreata from...