Saleh, Ali Marhuenda, Emilie Fabre, Christine Hassani, Zahra Weille, Jan de Boukhaddaoui, Hassan Guelfi, Sophie Maldonado, Igor Lima Hugnot, Jean- Philippe Duffau, Hugues
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Published in
Scientific Reports
Glioblastoma Multiforme (GBM) invasiveness renders complete surgical resection impossible and highly invasive Glioblastoma Initiating Cells (GICs) are responsible for tumour recurrence. Their dissemination occurs along pre-existing fibrillary brain structures comprising the aligned myelinated fibres of the corpus callosum (CC) and the laminin (LN)-...
Cao, Meiwen Xing, Ruirui Chang, Rui Wang, Yu Yan, Xuehai
Peptide-coordination self-assembly demonstrates great potential in the precise design of next-generation theranostic nanodrugs. It has the advantages of high biosafety, versatile system design, easy control over the self-assembled structures, facile incorporation of various functionalities, and greatly enhanced stability of the complex materials as...
Cao, Meiwen Xing, Ruirui Chang, Rui Wang, Yu Yan, Xuehai
Peptide-coordination self-assembly demonstrates great potential in the precise design of next-generation theranostic nanodrugs. It has the advantages of high biosafety, versatile system design, easy control over the self-assembled structures, facile incorporation of various functionalities, and greatly enhanced stability of the complex materials as...
Folkert, Ian W Devalaraja, Samir Linette, Gerald P Weber, Kristy Haldar, Malay
Published in
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Primary malignant bone tumors are rare, occur in all age groups, and include distinct entities such as osteosarcoma, Ewing sarcoma, and chondrosarcoma. Traditional treatment with some combination of chemotherapy, surgery, and radiation has reached the limit of efficacy, with substantial room for improvement in patient outcome. Furthermore, genomic ...
Jing, Bolin Luo, Yong Lin, Bingcheng Li, Jianjun Wang, Zhuo A. Du, Yuguang
Tumor metastasis is one of the main causes of cancer-related death, and it is difficult to study the whole process of tumor metastasis in vivo due to the complex physiological environment in the body. Therefore, it's crucial to develop simple and physiologically relevant in vitro cancer models to study the metastasis process, especially different p...
Jing, Bolin Luo, Yong Lin, Bingcheng Li, Jianjun Wang, Zhuo A. Du, Yuguang
Tumor metastasis is one of the main causes of cancer-related death, and it is difficult to study the whole process of tumor metastasis in vivo due to the complex physiological environment in the body. Therefore, it's crucial to develop simple and physiologically relevant in vitro cancer models to study the metastasis process, especially different p...
Li, Wenfang Hu, Xueyan Wang, Shuping Xing, Yan Wang, Hai Nie, Yi Liu, Tianqing Song, Kedong
Potential anti-cancer drugs are frequently of low efficacy in clinics due to the lack of predictive models or the insufficient employment of existing preclinical test systems. Three-dimensional (3D) in vitro engineered tumor models can better predict the efficacy of novel drugs by reproducing the in vivo tumor microenvironment. In this study, three...
Li, Wenfang Hu, Xueyan Wang, Shuping Xing, Yan Wang, Hai Nie, Yi Liu, Tianqing Song, Kedong
Potential anti-cancer drugs are frequently of low efficacy in clinics due to the lack of predictive models or the insufficient employment of existing preclinical test systems. Three-dimensional (3D) in vitro engineered tumor models can better predict the efficacy of novel drugs by reproducing the in vivo tumor microenvironment. In this study, three...
YI, HEEGYEONG jeong, young hun kim, yona choi, yeong-jin moon, hyo eun park, sung hye kang, kyung shin BAE, MIHYEON JANG, JIN AH youn, hyewon
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Shao, Jingxin Pijpers, Imke A. B. Cao, Shoupeng Williams, David S. Yan, Xuehai Li, Junbai Abdelmohsen, Loai K. E. A. van Hest, Jan C. M.
Morphologically discrete nanoarchitectures, which mimic the structural complexity of biological systems, are an increasingly popular design paradigm in the development of new nanomedical technologies. Herein, engineered polymeric stomatocytes are presented as a structural and functional mimic of red blood cells (RBCs) with multifunctional therapeut...
