Hudeček, Jan Voorwerk, Leonie van Seijen, Maartje Nederlof, Iris de Maaker, Michiel van den Berg, Jose van de Vijver, Koen K. Sikorska, Karolina Adams, Sylvia Demaria, Sandra
...
Published in
npj Breast Cancer
Stromal tumor-infiltrating lymphocytes (sTILs) are a potential predictive biomarker for immunotherapy response in metastatic triple-negative breast cancer (TNBC). To incorporate sTILs into clinical trials and diagnostics, reliable assessment is essential. In this review, we propose a new concept, namely the implementation of a risk-management frame...
Papadimitriou, Nikos Dimou, Niki Tsilidis, Konstantinos K. Banbury, Barbara Martin, Richard M. Lewis, Sarah J. Kazmi, Nabila Robinson, Timothy M. Albanes, Demetrius Aleksandrova, Krasimira
...
Published in
Nature Communications
Physical activity has been linked to lower risks of colorectal and breast cancer. Here, the authors present a Mendelian randomisation analysis supporting a potentially causal relationship between higher physical activity levels and lower risks of breast cancer and colorectal cancer.
Amgad, Mohamed Stovgaard, Elisabeth Specht Balslev, Eva Thagaard, Jeppe Chen, Weijie Dudgeon, Sarah Sharma, Ashish Kerner, Jennifer K. Denkert, Carsten Yuan, Yinyin
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Published in
npj Breast Cancer
Assessment of tumor-infiltrating lymphocytes (TILs) is increasingly recognized as an integral part of the prognostic workflow in triple-negative (TNBC) and HER2-positive breast cancer, as well as many other solid tumors. This recognition has come about thanks to standardized visual reporting guidelines, which helped to reduce inter-reader variabili...
Rolver, Michala G. Elingaard-Larsen, Line O. Andersen, Anne P. Counillon, Laurent Pedersen, Stine F.
Published in
Scientific Reports
The Na+/H+ exchanger-1 (NHE1) supports tumour growth, making NHE1 inhibitors of interest in anticancer therapy, yet their molecular effects are incompletely characterized. Here, we demonstrate that widely used pyrazinoylguanidine-type NHE1 inhibitors potently inhibit growth and survival of cancer cell spheroids, in a manner unrelated to NHE1 inhibi...
Holsbø, Einar Perduca, Vittorio Bongo, Lars Ailo Lund, Eiliv Birmelé, Etienne
Published in
BMC Research Notes
ObjectiveIn this exploratory work we investigate whether blood gene expression measurements predict breast cancer metastasis. Early detection of increased metastatic risk could potentially be life-saving. Our data comes from the Norwegian Women and Cancer epidemiological cohort study. The women who contributed to these data provided a blood sample ...
Abittan, Baruch Pachtman, Sarah Herman, Sarah Indelicato, Joseph Herman, Jonathan
Published in
Journal of cancer education : the official journal of the American Association for Cancer Education
To assess women's knowledge of personal breast cancer risk. Additionally, we aimed to determine how often physicians are discussing individualized risk assessments of breast cancer with their patients, and if those discussion affected risk perception. Surveys were distributed in radiology centers in New York and made available to patients presentin...
Derouane, Françoise Yombi, Jean-Cyr Baurain, Jean-François Danse, Etienne Komuta, Mina Yildiz, Halil
Published in
Acta clinica Belgica
We report the case of a 51 year-old female who complained of jaundice and weight loss. At the time of presentation, she had been in remission from a stage 2a ductal breast carcinoma for 58 months. The clinical presentation was suggestive of a primary pancreas cancer with liver metastases and retroperitoneal lymph nodes. We performed liver and pancr...
Frank, Sophie Carton, Matthieu Dubot, Coraline Campone, Mario Pistilli, Barbara Dalenc, Florence Mailliez, Audrey Lévy, Christelle D'Hondt, Veronique Debled, Marc
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Young age is a poor prognostic factor in early stage breast cancer (BC) but its value is less established in metastatic BC (MBC). We evaluated the impact of age at MBC diagnosis on overall survival (OS) across three age groups ( 60 years(y)).
Park, Sunre Sato, Yasuko Takita, Yuka Tamura, Noriko Ninomiya, Akira Kosugi, Teppei Sado, Mitsuhiro Nakagawa, Atsuo Takahashi, Maiko Hayashida, Tetsu
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Published in
Journal of pain and symptom management
Mindfulness-based interventions have been receiving growing attention in cancer care. The purpose of this randomized controlled trial is to examine the effectiveness of mindfulness-based cognitive therapy (MBCT) for psychological distress (anxiety and depression), fear of cancer recurrence (FCR), fatigue, spiritual well-being, and quality of life (...
Sridharan, Anush Eisenbrey, John R Stanczak, Maria Machado, Priscilla Merton, Daniel A Wilkes, Annina Sevrukov, Alexander Ojeda-Fournier, Haydee Mattrey, Robert F Wallace, Kirk
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Published in
Academic radiology
Breast cancer is the leading type of cancer among women. Visualization and characterization of breast lesions based on vascularity kinetics was evaluated using three-dimensional (3D) contrast-enhanced ultrasound imaging in a clinical study. Breast lesions (n = 219) were imaged using power Doppler imaging (PDI), 3D contrast-enhanced harmonic imaging...
