Published in Open Life Sciences
Objective Given the role of basic fibroblastic growth factor (bFGF) in tumor growth, it has been considered as a potential target for tumor therapy. In this study, we investigate the effect of bFGF antagonistic peptide on the growth and angiogenesis of 4T1 mammary carcinoma tumor (MCT) in BALB/c mice. Methods An engineered peptide was injected into...
Aromatase inhibitors have emerged as promising candidates for the treatment of breast cancer, which represents the second most prevalent cancer in females and is considered as the second leading cause of death among women. Inhibitory effect of 1.2.3 triazole were evaluated on the human aromatase enzyme and compared with the Letrozole (LTZ), the mos...
Aromatase inhibitors have emerged as promising candidates for the treatment of breast cancer, which represents the second most prevalent cancer in females and is considered as the second leading cause of death among women. Inhibitory effect of 1.2.3 triazole were evaluated on the human aromatase enzyme and compared with the Letrozole (LTZ), the mos...
Aromatase inhibitors have emerged as promising candidates for the treatment of breast cancer, which represents the second most prevalent cancer in females and is considered as the second leading cause of death among women. Inhibitory effect of 1.2.3 triazole were evaluated on the human aromatase enzyme and compared with the Letrozole (LTZ), the mos...
Aromatase inhibitors have emerged as promising candidates for the treatment of breast cancer, which represents the second most prevalent cancer in females and is considered as the second leading cause of death among women. Inhibitory effect of 1.2.3 triazole were evaluated on the human aromatase enzyme and compared with the Letrozole (LTZ), the mos...
Aromatase inhibitors have emerged as promising candidates for the treatment of breast cancer, which represents the second most prevalent cancer in females and is considered as the second leading cause of death among women. Inhibitory effect of 1.2.3 triazole were evaluated on the human aromatase enzyme and compared with the Letrozole (LTZ), the mos...
Aromatase inhibitors have emerged as promising candidates for the treatment of breast cancer, which represents the second most prevalent cancer in females and is considered as the second leading cause of death among women. Inhibitory effect of 1.2.3 triazole were evaluated on the human aromatase enzyme and compared with the Letrozole (LTZ), the mos...
This dissertation, by Yiren Hu, discusses how enhancer activity is regulated to drive rapid, coordinated transcriptional response to signals like estrogen and inflammatory stimuli. Enhancer elements play a central role in instructing precise spatiotemporal gene expression and are capable of activating target gene transcription from a long distance....
Breast cancer remains the most common malignant disease in women worldwide. Despite the advantages of early detection and improved treatments, studies into the mechanisms that initiate and drive breast cancer progression are still required. Recent studies have identified RUNX1, which is an essential transcription factor for hematopoiesis, is one of...
Breast cancer remains the most common malignant disease in women worldwide. Despite the advantages of early detection and improved treatments, studies into the mechanisms that initiate and drive breast cancer progression are still required. Recent studies have identified RUNX1, which is an essential transcription factor for hematopoiesis, is one of...
