Yi, Lingxian Ju, Yue He, Ying Yin, Xiushan Xu, Ye Weng, Tujun
Published in
Stem Cell Research & Therapy
BackgroundAge-related bone loss plays a vital role in the development of osteoporosis and osteoporotic fracture. Bone marrow stromal cell (BMSC) senescence is highly associated with osteoporosis and limits the application of BMSCs in regenerative medicine. Hypoxia is an essential component for maintaining the normal physiology of BMSCs. We have rep...
Summers, Selina Krkovic, Matija
Published in
European Journal of Orthopaedic Surgery & Traumatology
Background This study describes the outcomes of internal bone transport with magnetic nails in five cases of traumatic segmental femoral bone defects. Methods Five patients with open fracture of the femur and diaphyseal bone loss were included between May 2018 and August 2020. The mean femoral defect was 8.7 cm (range 5.6–16.0). Intervention We use...
Matsumoto, Taiichi Tsumura, Takuya Kishimoto, Katsuma Sano, Hirokazu Doi, Kohei Matsushita, Mutsumi Murakami, Hiroshi
Published in
JPRAS open
Two flaps, namely the free vascularized iliac bone graft supplied by the deep circumflex iliac artery (DCIA) and the superficial circumflex iliac artery perforator flap supplied by the superficial circumflex iliac artery (SCIA), can be individually harvested from a single surgical field. We report two cases treated by these free flaps for severe ha...
Chaushu, Liat Tal, Haim Sculean, Anton Fernández-Tomé, Blanca Chaushu, Gavriel
Published in
Clinical oral investigations
To assess complete blood count (CBC) dynamics following ligature removal and open flap debridement in experimental peri-implantitis in dogs. Seven male beagle dogs were included in the study. Four rough-surface implants were placed pair-wise in both sides of the mandible 14 weeks after tooth extraction. Second stage surgery was performed after 14 w...
Hameister, Rita Lohmann, Christoph H. Dheen, S. Thameem Singh, Gurpal Kaur, Charanjit
Published in
Bone & Joint Research
Aims This study aimed to examine the effects of tumour necrosis factor-alpha (TNF-α) on osteoblasts in metal wear-induced bone loss. Methods TNF-α immunoexpression was examined in periprosthetic tissues of patients with failed metal-on-metal hip arthroplasties and also in myeloid MM6 cells after treatment with cobalt ions. Viability and function of...
Wang, Xiao-Fei Meng, Yang Liu, Hao Hong, Ying Wang, Bei-Yu
Published in
World Journal of Clinical Cases
BACKGROUND Anterior bone loss (ABL) is a relatively easily neglected condition after cervical disc replacement (CDR). Whether this phenomenon is a radiological anomaly or a complication remains controversial. Several studies have reported the clinical characteristics of ABL and speculated on the pathogenic mechanism based on a certain type of artif...
Joaquim, Andrei Fernandes Lee, Nathan J Lehman, Ronald A Jr Tumialán, Luis M Riew, K Daniel
Published in
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Cervical disc arthroplasty (CDA) has become an increasingly popular treatment for cervical degenerative disc disease. One potential complication is osteolysis. However, current literature on this topic appears limited. The purpose of this study is to elucidate the incidence, aetiology, consequence, and subsequent treatment of this complication. A s...
Rachner, Tilman D Link-Rachner, Cornelia S Bornhäuser, Martin Hofbauer, Lorenz C
Published in
Bone
Allogeneic hematopoietic cell transplantation (HCT) is a potentially curative approach for patients with certain hematological diseases, including several forms of lymphoma and leukemia. Besides several treatment-associated risks, transplanted patients are at an increased risk of developing osteoporosis. The underlying pathophysiology is complex an...
Khan, Zehva Agarwal, Nidhi B Bhurani, Dinesh Khan, Mohd Ashif
Published in
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Hematopoietic stem cell transplantation (HSCT), including bone marrow transplantation, is the treatment of choice for many hematologic diseases, including hematologic malignancies and different types of anemia. The use of HSCT is increasing annually, mainly because advanced research that has been conducted in this area has exponentially expanded th...
Brent, Mikkel Bo Lodberg, Andreas Thomsen, Jesper Skovhus Brüel, Annemarie
Published in
MethodsX
Bone loss materializes rapidly after immobilization or mechanical unloading. Hind limb injection with botulinum toxin A (BTX) is a highly reproducible animal model for disuse-induced bone loss. Here we describe an easy-to-use and enhanced version of the method employing multiple hind limb injections with BTX to induce a pervasive muscle paralysis a...
