Strategies to Enhance the Biosynthesis of Monounsaturated Fatty Acids in Escherichia coli
status: Published online
Biodegradation of organic compounds in the coal gangue by Bacillus sp. into humic acid
Coal gangue (CG), one of the world's largest industrial solid wastes produced during coal mining, is extremely difficult to be used owing to its combined contents of clay minerals and organic macromolecules. This study explored a novel process of degrading the harmful organic compounds in the CG into humic acid using a biological method characteriz...
Biodegradation of organic compounds in the coal gangue by Bacillus sp. into humic acid
Coal gangue (CG), one of the world's largest industrial solid wastes produced during coal mining, is extremely difficult to be used owing to its combined contents of clay minerals and organic macromolecules. This study explored a novel process of degrading the harmful organic compounds in the CG into humic acid using a biological method characteriz...
Development of a live biotherapeutic throat spray with lactobacilli targeting respiratory viral infections
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Respiratory viruses such as influenza viruses, respiratory syncytial virus (RSV), and coronaviruses initiate infection at the mucosal surfaces of the upper respiratory tract (URT), where the resident respiratory microbiome has an important gatekeeper function. In contrast to gut-targeting administration of beneficial bacteria against respiratory vi...
Quality of life, control of treatment and satisfaction of patients with asthma in Bulgaria: a pilot study
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status: accepted
Dynamic feedback regulation for efficient membrane protein production using a small RNA-based genetic circuit in Escheri...
BACKGROUND: Membrane proteins (MPs) are an important class of molecules with a wide array of cellular functions and are part of many metabolic pathways. Despite their great potential-as therapeutic drug targets or in microbial cell factory optimization-many challenges remain for efficient and functional expression in a host such as Escherichia coli...
Straw lignin degradation by lignin peroxidase from Irpex lacteus cooperated with enzymes and small molecules
Objectives Maximizing the utility value of enzymes was achieved by exploring the effects of small molecules on the efficiency of lignin degradation by lignin peroxidase. Methods Using wheat straw as raw material and taking lignin degradation rate as index, it was found that laccase, glucose oxidase, malonic acid, citric acid, ZnSO4, CaCl2 could pro...
Straw lignin degradation by lignin peroxidase from Irpex lacteus cooperated with enzymes and small molecules
Objectives Maximizing the utility value of enzymes was achieved by exploring the effects of small molecules on the efficiency of lignin degradation by lignin peroxidase. Methods Using wheat straw as raw material and taking lignin degradation rate as index, it was found that laccase, glucose oxidase, malonic acid, citric acid, ZnSO4, CaCl2 could pro...
Base editing strategy to repair the CFTR 2789+5G > A splicing mutation
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status: published
Molecular detection of SARS-COV-2 in exhaled breath at the point-of-need
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The SARS-CoV-2 pandemic has highlighted the need for improved technologies to help control the spread of contagious pathogens. While rapid point-of-need testing plays a key role in strategies to rapidly identify and isolate infectious patients, current test approaches have significant shortcomings related to assay limitations and sample type. Direc...
