Accelerating flu protection
Published in Nature
Can the latest techniques speed up the dangerously slow production of flu vaccines?
Administração de hCG após a inseminação artificial eleva a taxa de gestação em cabras Saanen acíclicas submetidas a indu...
Edição dos resumos do XXIII Congresso Brasileiro de Reprodução Animal, Gramado, RS, Brasil, 15 a 17 de maio 2019.
Bioethicists clarify mitochondrial-therapy ban
Published in Nature
Optimization of the IPP-bypass mevalonate pathway and fed-batch fermentation for the production of isoprenol in Escheric...
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Isoprenol (3-methyl-3-buten-1-ol) is a drop-in biofuel and a precursor for commodity chemicals. Biological production of isoprenol via the mevalonate pathway has been developed and optimized extensively in Escherichia coli, but high ATP requirements and isopentenyl diphosphate (IPP) toxicity have made it difficult to achieve high titer, yield, and ...
Genome analysis and engineering of industrial lager brewing yeasts
Lager beer, also referred to as Pilsner, is the most popular alcoholic beverage in the world, with an annual consumption of almost 200 billion litres per year. To make lager beer, brewer’s wort is fermented with the yeast Saccharomyces pastorianus. This microorganism converts wort sugars into ethanol and contributes key flavour compounds to the bee...
mycelyso – high-throughput analysis of Streptomyces mycelium live cell imaging data
Published in BMC Bioinformatics
BackgroundStreptomycetes are filamentous microorganisms of high biotechnological relevance, especially for the production of antibiotics. In submerged cultures, the productivity of these microorganisms is closely linked to their growth morphology. Microfluidic lab-on-a-chip cultivation systems, coupled with automated time-lapse imaging, generate sp...
The bioengineering of cannabis
Published in Nature
Genetic modification could enable industrial-scale production of cannabinoids that have pharmaceutical potential.
A comparative study on nitric oxide and hypochlorite as a membrane cleaning agent to minimise biofilm growth in a membra...
© 2019 Elsevier B.V. Reverse osmosis concentrates (ROC) produced from water reclamation plants can threaten the environment if it is not appropriately treated before discharge. A membrane bioreactor (MBR) process to treat ROC was used in this project. In an MBR, fouling is an essential and inevitable phenomenon which leads to higher operational and...
From reproduction to the right to die: bioethics now
Published in Nature
Eric J. Topol weighs up a book on a field sprinting to keep up with biotechnology. An audience waves signs stating "Medicare for All" 2017
Optimizing CRISPR/Cas9 for Gene Silencing of SOD1 in Mouse Models of ALS
Mutations in the SOD1 gene are the best characterized genetic cause of amyotrophic lateral sclerosis (ALS) and account for ~20% of inherited cases and 1-3% of sporadic cases. The gene-editing tool Cas9 can silence mutant genes that cause disease, but effective delivery of CRISPR-Cas9 to the central nervous system (CNS) remains challenging. Here, I ...
